About the Authors

David T. Jones

Affiliation Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States of America

Prashanthi Vemuri

Affiliation Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America

Matthew C. Murphy

Affiliation Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America

Jeffrey L. Gunter

Affiliation Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America

Matthew L. Senjem

Affiliation Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America

Mary M. Machulda

Affiliation Department of Psychiatry/Psychology, Mayo Clinic, Rochester, Minnesota, United States of America

Scott A. Przybelski

Affiliation Department of Biomedical Statistic and Informatics, Mayo Clinic, Rochester, Minnesota, United States of America

Brian E. Gregg

Affiliation Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America

Kejal Kantarci

Affiliation Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America

David S. Knopman

Affiliation Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States of America

Bradley F. Boeve

Affiliation Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States of America

Ronald C. Petersen

Affiliation Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States of America

Clifford R. Jack Jr

jack.clifford@mayo.edu

Affiliation Department of Radiology, Mayo Clinic, Rochester, Minnesota, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DTJ CRJ. Performed the experiments: DTJ PV MCM. Analyzed the data: DTJ SAP BEG. Contributed reagents/materials/analysis tools: DTJ MCM JLG MLS. Wrote the paper: DTJ. Acquired data and obtained funding: DSK BFB RCP CRJ. Performed clinical assessment: DSK BFB RCP. Interpreted results: DTJ PV MCM JLG MLS MMM KK DSK BFB RCP CRJ. Critically reviewed manuscript: DTJ PV MCM JLG MLS MMM SAP BEG KK DSK BFB RCP CRJ.