About the Authors
- Robert Pilarski
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* E-mail: Robert.Pilarski@osumc.edu
Affiliation The Ohio State University Comprehensive Cancer Center and Department of Internal Medicine, Columbus, Ohio, United States of America
- Divya A. Patel
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Affiliation Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, Connecticut, United States of America
- Jeffrey Weitzel
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Affiliation Division of Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America
- Terri McVeigh
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Affiliation Discipline of Surgery, National University of Ireland, Galway, Ireland
- Jemima J. Dorairaj
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Affiliation Discipline of Surgery, National University of Ireland, Galway, Ireland
- Helen M. Heneghan
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Affiliation Discipline of Surgery, National University of Ireland, Galway, Ireland
- Nicola Miller
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Affiliation Discipline of Surgery, National University of Ireland, Galway, Ireland
- Joanne B. Weidhaas
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Affiliation Department of Therapeutic Radiology, Yale University, New Haven, Connecticut, United States of America
- Michael J. Kerin
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Affiliation Discipline of Surgery, National University of Ireland, Galway, Ireland
- Megan McKenna
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Affiliation Cancer Center of Santa Barbara, Santa Barbara, California, United States of America
- Xifeng Wu
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Affiliation Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
- Michelle Hildebrandt
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Affiliation Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
- Daniel Zelterman
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Affiliation Department of Epidemiology and Public Health, Yale University, New Haven, Connecticut, United States of America
- Sharon Sand
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Affiliation Division of Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America
- Lee P. Shulman
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Affiliation Division of Clinical Genetics, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, United States of America
Competing Interests
The authors have read the journal’s policy and Dr. Weidhaas has the following conflicts: She has patented the KRAS-variant through Yale University. This patent covers the discovery of the KRAS-variant and testing the KRAS-variant that is discussed in this application. This marker has been licensed to a company that she has co-founded. Dr. Weidhaas is not employed by this company, but is a consultant. The company has developed the KRAS-variant as a test. The Irish cohort was supported partially from a commercial source, the Galway Biobank. These things do not alter the authors’ adherence to all the PLoS ONE policies on sharing data and materials. The rest of the authors have no conflicts.
Author Contributions
Conceived and designed the experiments: RP JBW JW LS. Performed the experiments: TM JD HH NM MH SS. Analyzed the data: DP DZ. Contributed reagents/materials/analysis tools: RP JW MK XW LS MM. Wrote the paper: RP DP JW TM JD HH NM JBW MK MM XW MH DZ SS LS.