Efficient Maximum Likelihood Estimation of Kinetic Rate Constants from Macroscopic Currents

Andrey R. Stepanyuk; Anya L. Borisyuk; Pavel V. Belan

doi:10.1371/journal.pone.0029731

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Open Access

Peer-reviewed

Research Article

Efficient Maximum Likelihood Estimation of Kinetic Rate Constants from Macroscopic Currents

Andrey R. Stepanyuk,

Affiliations Bogomoletz Institute of Physiology, Kiev, Ukraine, State Key Laboratory of Molecular and Cellular Biology, Kiev, Ukraine
⨯
Anya L. Borisyuk,

Affiliations Bogomoletz Institute of Physiology, Kiev, Ukraine, State Key Laboratory of Molecular and Cellular Biology, Kiev, Ukraine
⨯
Pavel V. Belan

* E-mail: pasha@biph.kiev.ua

Affiliations Bogomoletz Institute of Physiology, Kiev, Ukraine, State Key Laboratory of Molecular and Cellular Biology, Kiev, Ukraine
⨯

Efficient Maximum Likelihood Estimation of Kinetic Rate Constants from Macroscopic Currents

Andrey R. Stepanyuk,
Anya L. Borisyuk,
Pavel V. Belan

Published: December 29, 2011
https://doi.org/10.1371/journal.pone.0029731

About the Authors

Andrey R. Stepanyuk

Affiliations Bogomoletz Institute of Physiology, Kiev, Ukraine, State Key Laboratory of Molecular and Cellular Biology, Kiev, Ukraine

Anya L. Borisyuk

Affiliations Bogomoletz Institute of Physiology, Kiev, Ukraine, State Key Laboratory of Molecular and Cellular Biology, Kiev, Ukraine

Pavel V. Belan

* E-mail: pasha@biph.kiev.ua

Affiliations Bogomoletz Institute of Physiology, Kiev, Ukraine, State Key Laboratory of Molecular and Cellular Biology, Kiev, Ukraine

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AS. Performed the experiments: AS AB. Analyzed the data: AS. Contributed reagents/materials/analysis tools: AS AB PB. Wrote the paper: AS AB PB.

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