About the Authors

Joshua L. Roffman

jroffman@partners.org

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

Adam Z. Nitenson

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

Yigal Agam

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

Marlisa Isom

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

Jesse S. Friedman

† Deceased.

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

Kara A. Dyckman

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

David G. Brohawn

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

Jordan W. Smoller

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

Donald C. Goff

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

Dara S. Manoach

Affiliation Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, United States of America

Competing Interests

The authors have read the journal's policy and have the following conflicts: Drs. Roffman and Goff have filed a U.S. patent application for the use of MTHFR genotype to predict treatment response in schizophrenia. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JLR DSM DCG. Performed the experiments: JWS DGB AZN YA MI JSF KAD. Analyzed the data: AZN DGB JLR. Contributed reagents/materials/analysis tools: DCG. Wrote the paper: JLR DSM.