About the Authors
- Kaisa Silander
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* E-mail: kaisa.silander@ktl.fi
Affiliations Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, FIMM, Institute for Molecular Medicine Finland, Helsinki, Finland
- Mervi Alanne
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Contributed equally to this work with: Mervi Alanne, Kati Kristiansson
Affiliations Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, FIMM, Institute for Molecular Medicine Finland, Helsinki, Finland
- Kati Kristiansson
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Contributed equally to this work with: Mervi Alanne, Kati Kristiansson
Affiliations Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, FIMM, Institute for Molecular Medicine Finland, Helsinki, Finland
- Olli Saarela
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Affiliation Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
- Samuli Ripatti
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Affiliations Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, FIMM, Institute for Molecular Medicine Finland, Helsinki, Finland, Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
- Kirsi Auro
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Affiliations Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, FIMM, Institute for Molecular Medicine Finland, Helsinki, Finland
- Juha Karvanen
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Affiliation Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
- Sangita Kulathinal
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Affiliation Indic Society for Education and Development, Nashik, India
- Matti Niemelä
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Affiliation Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
- Pekka Ellonen
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Affiliations Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, FIMM, Institute for Molecular Medicine Finland, Helsinki, Finland
- Erkki Vartiainen
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Affiliation Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
- Pekka Jousilahti
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Affiliation Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
- Janna Saarela
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Affiliations Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, FIMM, Institute for Molecular Medicine Finland, Helsinki, Finland
- Kari Kuulasmaa
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Affiliation Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
- Alun Evans
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Affiliation The Queen's University of Belfast, Belfast, United Kingdom
- Markus Perola
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Affiliations Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, FIMM, Institute for Molecular Medicine Finland, Helsinki, Finland, Department of Medical Genetics, University of Helsinki, Helsinki, Finland
- Veikko Salomaa
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Affiliation Department of Health Promotion and Chronic Disease Prevention, National Public Health Institute, Helsinki, Finland
- Leena Peltonen
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Affiliations Department of Molecular Medicine, National Public Health Institute, Helsinki, Finland, FIMM, Institute for Molecular Medicine Finland, Helsinki, Finland, Department of Medical Genetics, University of Helsinki, Helsinki, Finland, Department of Human Genetics, Wellcome Trust Sanger Institute, Cambridge, United Kingdom, The Broad Institute of MIT and Harvard, Boston, Massachusetts, United States of America
Competing Interests
The authors have declared that no competing interests exist.
Author Contributions
Conceived and designed the experiments: KS MA KKristiansson KA JK SK KKuulasmaa AE MP VS LP. Performed the experiments: KS MA KKristiansson KA PE JS. Analyzed the data: KS MA KKristiansson OS SR JK SK KKuulasmaa MP LP. Contributed reagents/materials/analysis tools: MN EV PJ VS. Wrote the paper: KS MA KKristiansson OS SR KA JK SK MN PE EV PJ JS KKuulasmaa AE MP VS LP. Responsible for the DNA sample management: MA. Participated in SNP selection: MA KKristiansson KA MP. Participated in genotyping: MA KKristiansson KA PE JS. Participated in data analyses: KS MA KKristiansson SR MP. Responsible for the statistical analysis of the data: OS. Participated in data management, case-cohort selection, and statistical analysis: JK SK. Responsible for phenotype data quality assessment: MN. Participated in recruitment of the FINRISK cohorts: EV PJ VS. Participated in whole genome amplification of DNA samples: JS. Responsible for data management and case-cohort selection: KKuulasmaa. Participated in study design: KS KKuulasmaa AE MP VS. MORGAM Project Coordinator: AE. Participated in the assessment of the clinical diagnoses: VS. Has had an overall responsibility of the study design and data analyses: LP. Responsible for SNP selection: KS. Responsible for DNA sample quality, whole genome amplification of DNA, genotyping, and writing the manuscript: KS. Holds overall responsibility of the data presented: KS.