About the Authors

Nicholas Guido

Affiliation Research & Development, Gen9 Inc, Cambridge, Massachusetts, United States of America

Elena Starostina

Affiliation Research & Development, Gen9 Inc, Cambridge, Massachusetts, United States of America

Devin Leake

Affiliation Research & Development, Gen9 Inc, Cambridge, Massachusetts, United States of America

Ishtiaq Saaem

isaaem@gen9bio.com

Affiliation Research & Development, Gen9 Inc, Cambridge, Massachusetts, United States of America

Competing Interests

N. Guido, E. Starostina, D. Leake, and I. Saaem are employed or were formerly employed by Gen9 Inc, one of the funders of this study. Some of the materials used in this study are products sold by Gen9 Inc (synthetic oligonucleotides and synthetic genes) and are subject to use restrictions or licenses. There are no further patents, products in development, or marketed products referenced in this article to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: NG IS. Performed the experiments: NG ES. Analyzed the data: NG ES. Wrote the paper: NG ES DL IS.