About the Authors
- Bee Luan Khoo
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Contributed equally to this work with: Bee Luan Khoo, Majid Ebrahimi Warkiani, Daniel Shao-Weng Tan
Affiliation Mechanobiology Institute, National University of Singapore, Singapore, Singapore
- Majid Ebrahimi Warkiani
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Contributed equally to this work with: Bee Luan Khoo, Majid Ebrahimi Warkiani, Daniel Shao-Weng Tan
Affiliation BioSystems and Micromechanics (BioSyM) IRG, Singapore-MIT Alliance for Research and Technology (SMART) Centre, Singapore, Singapore
- Daniel Shao-Weng Tan
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Contributed equally to this work with: Bee Luan Khoo, Majid Ebrahimi Warkiani, Daniel Shao-Weng Tan
Affiliations Department of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore, Cancer Therapeutics Research Laboratory, National Cancer Centre Singapore, Singapore, Singapore
- Ali Asgar S. Bhagat
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Affiliation Clearbridge BioMedics Pte Ltd, Singapore, Singapore
- Darryl Irwin
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Affiliation Sequenom Inc, San Diego, California, United States of America
- Dawn Pingxi Lau
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Affiliations Department of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore, Cancer Therapeutics Research Laboratory, National Cancer Centre Singapore, Singapore, Singapore
- Alvin S. T. Lim
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Affiliation Department of Pathology, Singapore General Hospital, Singapore, Singapore
- Kiat Hon Lim
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Affiliation Department of Pathology, Singapore General Hospital, Singapore, Singapore
- Sai Sakktee Krisna
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Affiliations Department of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore, Cancer Therapeutics Research Laboratory, National Cancer Centre Singapore, Singapore, Singapore
- Wan-Teck Lim
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Affiliation Department of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
- Yoon Sim Yap
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Affiliation Department of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
- Soo Chin Lee
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Affiliation Department of Hematology-Oncology, National University Hospital, Singapore, Singapore
- Ross A. Soo
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Affiliation Department of Hematology-Oncology, National University Hospital, Singapore, Singapore
- Jongyoon Han
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* E-mail: jyhan@mit.edu (JH); ctlim@nus.edu.sg (CTL)
Affiliations BioSystems and Micromechanics (BioSyM) IRG, Singapore-MIT Alliance for Research and Technology (SMART) Centre, Singapore, Singapore, Department of Electrical Engineering and Computer Science, Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
- Chwee Teck Lim
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* E-mail: jyhan@mit.edu (JH); ctlim@nus.edu.sg (CTL)
Affiliations Mechanobiology Institute, National University of Singapore, Singapore, Singapore, BioSystems and Micromechanics (BioSyM) IRG, Singapore-MIT Alliance for Research and Technology (SMART) Centre, Singapore, Singapore, Department of Biomedical Engineering, National University of Singapore, Singapore, Singapore, Clearbridge BioMedics Pte Ltd, Singapore, Singapore
Competing Interests
AASB is an employee of Clearbridge BioMedics Pte Ltd which commercialized the technology described here. AASB, JH and CTL, along with others, also have filed a patent application on the technology. Pending patent: Microfluidics Sorter for Cell Detection and Isolation and number PCT/US2011/027276. A product based on this technology is currently being developed by Clearbridge Biomedics Pte Ltd. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: BLK MEW DSWT JH CTL. Performed the experiments: BLK MEW DI. Analyzed the data: BLK MEW DSWT CTL. Contributed reagents/materials/analysis tools: DSWT AASB DI DPL ASTL KHL SSK WTL YSY SCL RAS CTL. Wrote the paper: BLK MEW DSWT JH CTL.