The Co-Existence of the IL-18+183 A/G and MMP-9 -1562 C/T Polymorphisms Is Associated with Clinical Events in Coronary Artery Disease Patients

Trine B. Opstad; Alf Å. Pettersen; Harald Arnesen; Ingebjørg Seljeflot

doi:10.1371/journal.pone.0074498

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Open Access

Peer-reviewed

Research Article

The Co-Existence of the IL-18+183 A/G and MMP-9 -1562 C/T Polymorphisms Is Associated with Clinical Events in Coronary Artery Disease Patients

Trine B. Opstad ,

* E-mail: trineoa@medisin.uio.no

Affiliations Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway, Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway
⨯
Alf Å. Pettersen,

Affiliations Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway, Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway
⨯
Harald Arnesen,

Affiliations Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway, Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway, Faculty of Medicine, University of Oslo, Oslo, Norway
⨯
Ingebjørg Seljeflot

Affiliations Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway, Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway, Faculty of Medicine, University of Oslo, Oslo, Norway
⨯

The Co-Existence of the IL-18+183 A/G and MMP-9 -1562 C/T Polymorphisms Is Associated with Clinical Events in Coronary Artery Disease Patients

Trine B. Opstad,
Alf Å. Pettersen,
Harald Arnesen,
Ingebjørg Seljeflot

Published: September 5, 2013
https://doi.org/10.1371/journal.pone.0074498

About the Authors

Trine B. Opstad

* E-mail: trineoa@medisin.uio.no

Affiliations Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway, Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway

Alf Å. Pettersen

Affiliations Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway, Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway

Harald Arnesen

Affiliations Center for Clinical Heart Research, Department of Cardiology, Oslo University Hospital, Ullevål, Oslo, Norway, Center for Heart Failure Research, Oslo University Hospital, Oslo, Norway, Faculty of Medicine, University of Oslo, Oslo, Norway

Ingebjørg Seljeflot

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TBO AÅP HA IS. Performed the experiments: TBO. Analyzed the data: TBO. Contributed reagents/materials/analysis tools: AÅP IS. Wrote the paper: TBO IS.

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Medical risk factors
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Myocardial infarction
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Cardiovascular disease risk
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Stable coronary artery disease
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Type 2 diabetes risk
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Haplotypes
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Nitrates
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Atherosclerosis
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