About the Authors

Alexander Mitsos

Contributed equally to this work with: Alexander Mitsos, Ioannis N. Melas

Affiliation Dept. of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, Massachussetts, United States of America

Ioannis N. Melas

Contributed equally to this work with: Alexander Mitsos, Ioannis N. Melas

Affiliation Dept. of Mechanical Engineering, National Technical University of Athens, Zografou, Greece

Melody K. Morris

Affiliations Dept. of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachussetts, United States of America, Center for Cell Decision Processes, Massachusetts Institute of Technology and Harvard Medical School, Boston, Massachusetts, United States of America

Julio Saez-Rodriguez

Affiliation European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, United Kingdom

Douglas A. Lauffenburger

Affiliations Dept. of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachussetts, United States of America, Center for Cell Decision Processes, Massachusetts Institute of Technology and Harvard Medical School, Boston, Massachusetts, United States of America

Leonidas G. Alexopoulos

leoalexopoulos@gmail.com

Affiliation Dept. of Mechanical Engineering, National Technical University of Athens, Zografou, Greece

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived the Non Linear Programming formulation: AM MKM INM. Implemented the Non Linear Programming formulation: AM. Edited the manuscript: MKM JSR AM DAL. Analyzed the data: INM. Contributed reagents/materials/analysis tools: AM JSR INM. Wrote the paper: INM LGA.