About the Authors
- Sarah Burl
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* E-mail: s.burl@imperial.ac.uk
Affiliations Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia, Department of Paediatrics, Imperial College London, Paddington, London, United Kingdom
- John Townend
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Affiliation Statistics Department, Medical Research Council (UK) The Gambia, Fajara, The Gambia
- Jainaba Njie-Jobe
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Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
- Momodou Cox
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Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
- Uche J. Adetifa
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Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
- Ebrima Touray
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Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
- Victoria J. Philbin
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Affiliation Division of Infectious Diseases, Department of Medicine, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America
- Christy Mancuso
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Affiliation Division of Infectious Diseases, Department of Medicine, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America
- Beate Kampmann
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Affiliations Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia, Department of Paediatrics, Imperial College London, Paddington, London, United Kingdom
- Hilton Whittle
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Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
- Assan Jaye
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Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
- Katie L. Flanagan
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Contributed equally to this work with: Katie L. Flanagan, Ofer Levy
Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
- Ofer Levy
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Contributed equally to this work with: Katie L. Flanagan, Ofer Levy
Affiliation Division of Infectious Diseases, Department of Medicine, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America
Competing Interests
The laboratory of OL receives sponsored research support from VentiRx Pharmaceuticals, which manufactures certain TLR8 agonists although distinct from those studied in this manuscript. This does not alter the authors' adherence to all the PLoS ONE policies on sharing data and materials. There are no other known competing interests.
Author Contributions
Conceived and designed the experiments: SB KLF OL AJ HW VJP. Performed the experiments: SB JNJ MC CM. Analyzed the data: SB JT OL. Contributed reagents/materials/analysis tools: SB JT KLF OL. Wrote the paper: SB OL KLF BK. Acquired field data and ran field team: SB UJA ET. Contributed to review and editing of manuscript: SB JT JNJ MC UJA ET VJP CM BK HW AJ KLF OL. Interpretation of the data: SB OL KLF BK.