Age-Dependent Maturation of Toll-Like Receptor-Mediated Cytokine Responses in Gambian Infants

Sarah Burl; John Townend; Jainaba Njie-Jobe; Momodou Cox; Uche J. Adetifa; Ebrima Touray; Victoria J. Philbin; Christy Mancuso; Beate Kampmann; Hilton Whittle; Assan Jaye; Katie L. Flanagan; Ofer Levy

doi:10.1371/journal.pone.0018185

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Open Access

Peer-reviewed

Research Article

Age-Dependent Maturation of Toll-Like Receptor-Mediated Cytokine Responses in Gambian Infants

Sarah Burl ,

* E-mail: s.burl@imperial.ac.uk

Affiliations Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia, Department of Paediatrics, Imperial College London, Paddington, London, United Kingdom
⨯
John Townend,

Affiliation Statistics Department, Medical Research Council (UK) The Gambia, Fajara, The Gambia
⨯
Jainaba Njie-Jobe,

Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
⨯
Momodou Cox,

Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
⨯
Uche J. Adetifa,

Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
⨯
Ebrima Touray,

Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
⨯
Victoria J. Philbin,

Affiliation Division of Infectious Diseases, Department of Medicine, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Christy Mancuso,

Affiliation Division of Infectious Diseases, Department of Medicine, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Beate Kampmann,

Affiliations Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia, Department of Paediatrics, Imperial College London, Paddington, London, United Kingdom
⨯
Hilton Whittle,

Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
⨯
Assan Jaye,

Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
⨯
Katie L. Flanagan ,

Contributed equally to this work with: Katie L. Flanagan, Ofer Levy

Affiliation Infant Immunology, Medical Research Council (UK) The Gambia, Fajara, The Gambia
⨯
Ofer Levy

Contributed equally to this work with: Katie L. Flanagan, Ofer Levy

Affiliation Division of Infectious Diseases, Department of Medicine, Children's Hospital Boston and Harvard Medical School, Boston, Massachusetts, United States of America
⨯

Age-Dependent Maturation of Toll-Like Receptor-Mediated Cytokine Responses in Gambian Infants

Sarah Burl,
John Townend,
Jainaba Njie-Jobe,
Momodou Cox,
Uche J. Adetifa,
Ebrima Touray,
Victoria J. Philbin,
Christy Mancuso,
Beate Kampmann,
Hilton Whittle

Published: April 13, 2011
https://doi.org/10.1371/journal.pone.0018185

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Toll-like receptors
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Infants
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Immune response
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