Visceral leishmaniasis (VL) remains a major public health challenge in East Africa, particularly in Ethiopia. Clinical trials on VL often exclude patients with severe comorbidities or laboratory abnormalities, limiting the generalizability of evidence used to guide real-world management. This study comprehensively characterised the clinical profile, treatment outcomes, and mortality of VL patients treated in a referral centre. Ayele et al. 2026
Image Credit: Eleni Ayele
Viewpoints
Emergence of Marburg virus disease in Ethiopia: Implications for public health preparedness and its impact on Ethiopia’s health system
PLOS Neglected Tropical Diseases: published June 5, 2026 | https://doi.org/10.1371/journal.pntd.0014394
Toxoplasmosis meets the World Health Organization criteria for a neglected tropical disease
PLOS Neglected Tropical Diseases: published June 25, 2026 | https://doi.org/10.1371/journal.pntd.0014425
Reviews
Accelerating vaccine research and development for skin neglected tropical diseases: A case for leishmaniasis, leprosy, and Buruli ulcer
PLOS Neglected Tropical Diseases: published June 5, 2026 | https://doi.org/10.1371/journal.pntd.0014375
Prevalence of hookworm infection and its proportion among pregnant women with intestinal helminth infection in Ethiopia: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published June 10, 2026 | https://doi.org/10.1371/journal.pntd.0014376
Amebiasis as a neglected tropical disease: Current knowledge gaps and future directions
PLOS Neglected Tropical Diseases: published June 22, 2026 | https://doi.org/10.1371/journal.pntd.0014423
Encephalomyocarditis virus (EMCV): An overlooked threat to primates
PLOS Neglected Tropical Diseases: published June 23, 2026 | https://doi.org/10.1371/journal.pntd.0014409
Research Articles
The cost-effectiveness of Wolbachia-based biocontrol interventions for dengue: A scoping review of the available evidence
PLOS Neglected Tropical Diseases: published June 1, 2026 | https://doi.org/10.1371/journal.pntd.0014395
High infection risk of intestinal helminths despite WASH interventions: A cross-sectional study in Khammouane province, Lao PDR
PLOS Neglected Tropical Diseases: published June 1, 2026 | https://doi.org/10.1371/journal.pntd.0014388
Performance of fecal inflammatory biomarkers to identify watery shigellosis: Findings from the Enterics for Global Health (EFGH) Shigella surveillance study
PLOS Neglected Tropical Diseases: published June 1, 2026 | https://doi.org/10.1371/journal.pntd.0014025
Factors affecting detection and quantification of Schistosoma haematobium eggs in pooled urine samples
PLOS Neglected Tropical Diseases: published June 1, 2026 | https://doi.org/10.1371/journal.pntd.0014407
Landmark-based morphometrics with fewer landmarks: Some examples for medical entomology
PLOS Neglected Tropical Diseases: published June 2, 2026 | https://doi.org/10.1371/journal.pntd.0014386
VP1–141 is a determinant of a Vero cell-adapted Coxsackievirus A10 for vaccine development
PLOS Neglected Tropical Diseases: published June 2, 2026 | https://doi.org/10.1371/journal.pntd.0014396
Geographical disparities and programmatic determinants of hydrocele surgery and lymphoedema management coverage for lymphatic filariasis in the Democratic Republic of the Congo, 2018–2024: A national analysis of routine programme data
PLOS Neglected Tropical Diseases: published June 2, 2026 | https://doi.org/10.1371/journal.pntd.0014406
CD163⁺ monocytes and soluble CD163 as prognostic indicators in severe fever with thrombocytopenia syndrome: An integrative analysis
PLOS Neglected Tropical Diseases: published June 3, 2026 | https://doi.org/10.1371/journal.pntd.0014416
Knowledge, attitude, and prevention practices of cutaneous leishmaniasis in highly-endemic rural areas of Kandahar province, Afghanistan: A large cross-sectional community-based study
PLOS Neglected Tropical Diseases: published June 3, 2026 | https://doi.org/10.1371/journal.pntd.0013575
A snapshot of selected neglected tropical disease research using the World Health Organization International Clinical Trials Registry Platform database, 1999–2023
PLOS Neglected Tropical Diseases: published June 3, 2026 | https://doi.org/10.1371/journal.pntd.0014338
Genomic and phylogenetic characterization of severe fever with thrombocytopenia syndrome virus in companion animals in Korea, 2023–2024
PLOS Neglected Tropical Diseases: published June 4, 2026 | https://doi.org/10.1371/journal.pntd.0014305
Epidemiological insights and genetic diversity of the Duffy binding protein of Plasmodium vivax in Duffy-negative Cameroonians
PLOS Neglected Tropical Diseases: published June 4, 2026 | https://doi.org/10.1371/journal.pntd.0014404
Estimating the distributional impact of improving access to snake antivenom in urban and rural Lao People’s Democratic Republic: An extended cost-effectiveness analysis
PLOS Neglected Tropical Diseases: published June 4, 2026 | https://doi.org/10.1371/journal.pntd.0014420
Prevalence of multiple human intestinal parasites across diverse environments in Madagascar
PLOS Neglected Tropical Diseases: published June 4, 2026 | https://doi.org/10.1371/journal.pntd.0014380
Development of a deep learning based framework for classification of Indian venomous snakes integrated with explainable artificial intelligence for primary and emergency care providers
PLOS Neglected Tropical Diseases: published June 5, 2026 | https://doi.org/10.1371/journal.pntd.0014147
Severe visceral leishmaniasis in Ethiopia: Outcomes, co-infections and mortality in a prospective real-world cohort
PLOS Neglected Tropical Diseases: published June 5, 2026 | https://doi.org/10.1371/journal.pntd.0013878
A systematic mapping review of therapeutic clinical trials in dengue
PLOS Neglected Tropical Diseases: published June 5, 2026 | https://doi.org/10.1371/journal.pntd.0014382
An intuitive sampling framework for setting-specific decision-making in soil-transmitted helminthiasis control programs
PLOS Neglected Tropical Diseases: published June 5, 2026 | https://doi.org/10.1371/journal.pntd.0014026
Plant-based therapeutics for leishmaniasis: A systematic review emphasizing human studies and clinical trial evidence
PLOS Neglected Tropical Diseases: published June 5, 2026 | https://doi.org/10.1371/journal.pntd.0014389
Xeno-monitoring the impact of Vector Control on trypanosome transmission in the Forecariah sleeping sickness focus (Guinea)
PLOS Neglected Tropical Diseases: published June 5, 2026 | https://doi.org/10.1371/journal.pntd.0013598
Discovery of a novel coltivirus in a newly identified Bat Bug Species (Heteroptera: Cimicidae) in Cambodia
PLOS Neglected Tropical Diseases: published June 8, 2026 | https://doi.org/10.1371/journal.pntd.0014372
Predictive Modeling of Localized Mobile App to Improve Snakebite Management in Ghana
PLOS Neglected Tropical Diseases: published June 8, 2026 | https://doi.org/10.1371/journal.pntd.0014435
Plasma proteomics improves risk prediction in heart failure and reveals unique biology in chronic chagas cardiomyopathy
PLOS Neglected Tropical Diseases: published June 8, 2026 | https://doi.org/10.1371/journal.pntd.0014370
Stranger swings: Temperature-dependent upsides and downsides of a densovirus in Aedes albopictus
PLOS Neglected Tropical Diseases: published June 8, 2026 | https://doi.org/10.1371/journal.pntd.0014405
Multivariate predictive model for predicting in-hospital mortality in HIV-associated talaromycosis: a multicenter retrospective study
PLOS Neglected Tropical Diseases: published June 8, 2026 | https://doi.org/10.1371/journal.pntd.0014432
Preclinical animal models for onchocerciasis and loiasis: A systematic review of applications in drug screening
PLOS Neglected Tropical Diseases: published June 8, 2026 | https://doi.org/10.1371/journal.pntd.0014401
Beneficiary feedback mechanisms: Exploring ways to systematically integrate community feedback in mass drug administration delivery for NTDs
PLOS Neglected Tropical Diseases: published June 8, 2026 | https://doi.org/10.1371/journal.pntd.0014373
Ecological signature on the epidemiological dynamics of severe fever with thrombocytopenia syndrome
PLOS Neglected Tropical Diseases: published June 8, 2026 | https://doi.org/10.1371/journal.pntd.0014408
Government health care worker training needs for intestinal schistosomiasis morbidity management
PLOS Neglected Tropical Diseases: published June 8, 2026 | https://doi.org/10.1371/journal.pntd.0014419
Identification of a persistent Ascaris-derived Kalirin epitope associated with chronic T cell activation in the lung
PLOS Neglected Tropical Diseases: published June 9, 2026 | https://doi.org/10.1371/journal.pntd.0014434
Experiences and perceptions on diagnostic delay of leprosy by affected people in Colombia: A qualitative study
PLOS Neglected Tropical Diseases: published June 11, 2026 | https://doi.org/10.1371/journal.pntd.0014412
Comparison of a recombinant endonuclease III protein and its synthetic peptides in ELISA for the diagnosis of tegumentary leishmaniasis using human serum and urine samples: A preliminary study
PLOS Neglected Tropical Diseases: published June 15, 2026 | https://doi.org/10.1371/journal.pntd.0014440
Shared risk factors for malaria and schistosomiasis co-infection: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published June 15, 2026 | https://doi.org/10.1371/journal.pntd.0014369
Molecular evidence of Echinococcus canadensis (G6/G7) predominance in Mongolian livestock and its implications for control
PLOS Neglected Tropical Diseases: published June 15, 2026 | https://doi.org/10.1371/journal.pntd.0014433
Giardiasis in Japan, the United States of America, and Europe from 2007 to 2023, highlighting a decline during the COVID-19 pandemic
PLOS Neglected Tropical Diseases: published June 15, 2026 | https://doi.org/10.1371/journal.pntd.0014428
Systematic review and meta-analysis of insecticide resistance status and mechanisms in the arbovirus vector Aedes aegypti from Nigeria
PLOS Neglected Tropical Diseases: published June 15, 2026 | https://doi.org/10.1371/journal.pntd.0014421
Epidemiology, seroprevalence, and circulation of Chikungunya virus in Southern Africa (SADC region): A systematic review
PLOS Neglected Tropical Diseases: published June 16, 2026 | https://doi.org/10.1371/journal.pntd.0014438
Post-market surveillance of albendazole tablet brands in Kenya: Implications for deworming programs and clinical outcomes
PLOS Neglected Tropical Diseases: published June 16, 2026 | https://doi.org/10.1371/journal.pntd.0014449
The health and economic burden of podoconiosis in East Africa: A systematic review and meta-analysis of health outcomes with narrative synthesis of economic evidence
PLOS Neglected Tropical Diseases: published June 17, 2026 | https://doi.org/10.1371/journal.pntd.0014427
Inhibition of Toxoplasma gondii proliferation by dimethyl itaconate: Evidence from in vitro and in vivo studies
PLOS Neglected Tropical Diseases: published June 18, 2026 | https://doi.org/10.1371/journal.pntd.0014454
Paucibacillary leprosy presenting as fibular neuropathy: A case of autochthonous zoonotic exposure in endemic Florida
PLOS Neglected Tropical Diseases: published June 22, 2026 | https://doi.org/10.1371/journal.pntd.0014456
Epidemiological characteristics and importation patterns of imported dengue fever in southwest border regions of China
PLOS Neglected Tropical Diseases: published June 22, 2026 | https://doi.org/10.1371/journal.pntd.0014446
The nuclear basket nucleoporin MLP1 is required to maintain nuclear integrity, and mitotic fidelity in Trypanosoma brucei
PLOS Neglected Tropical Diseases: published June 22, 2026 | https://doi.org/10.1371/journal.pntd.0013922
Survey on the current status of rabies post-exposure prophylaxis clinics construction and the surveillance of rabies-exposed individuals in China, 2022
PLOS Neglected Tropical Diseases: published June 22, 2026 | https://doi.org/10.1371/journal.pntd.0014011
Social marginalisation, environmental degradation and Toxoplasma gondii exposure in urban informal settlements in Brazil
PLOS Neglected Tropical Diseases: published June 22, 2026 | https://doi.org/10.1371/journal.pntd.0014453
Snakes and snakebites in the munduruku cosmology and medicine, central Brazilian Amazonia
PLOS Neglected Tropical Diseases: published June 22, 2026 | https://doi.org/10.1371/journal.pntd.0014462
An immune system for the city: A cluster-randomized trial of a new paradigm for surveillance and control of disease vectors
PLOS Neglected Tropical Diseases: published June 22, 2026 | https://doi.org/10.1371/journal.pntd.0014464
Non-typhoidal Salmonella co-infect and complicate Plasmodium falciparum malaria in children under-five: A prospective cohort study on clinical presentation and outcome in Kisantu district hospital, DR Congo
PLOS Neglected Tropical Diseases: published June 24, 2026 | https://doi.org/10.1371/journal.pntd.0014457
Seasonal dynamic modeling for real-time prediction of human brucellosis epidemiological trends in Gansu, Guangdong and Sichuan Provinces, China
PLOS Neglected Tropical Diseases: published June 25, 2026 | https://doi.org/10.1371/journal.pntd.0014443
Clinical and epidemiological characteristics of leptospirosis in patients under and over 5 years of age in primary health centers in the Peruvian Amazon, 2022–2024
PLOS Neglected Tropical Diseases: published June 25, 2026 | https://doi.org/10.1371/journal.pntd.0013473
Assessing the sustainability of Rwanda’s mass drug administration program for schistosomiasis and soil-transmitted helminthiasis: A mixed-methods application of the program sustainability assessment tool
PLOS Neglected Tropical Diseases: published June 25, 2026 | https://doi.org/10.1371/journal.pntd.0014455
Contrasting geographic patterns of parasite and hantavirus diversity in the rodent Oligoryzomys longicaudatus (Rodentia, Cricetidae)
PLOS Neglected Tropical Diseases: published June 26, 2026 | https://doi.org/10.1371/journal.pntd.0014424
A rapid immunochromatographic test for antibody detection as a new tool for monitoring malaria caused by Plasmodium vivax
PLOS Neglected Tropical Diseases: published June 26, 2026 | https://doi.org/10.1371/journal.pntd.0014447
Molecular detection and subtype characterization of Blastocystis in diarrheal outpatients in Shanghai, China: A case-control study
PLOS Neglected Tropical Diseases: published June 26, 2026 | https://doi.org/10.1371/journal.pntd.0014461
Long-term disability outcomes in Hansen’s disease: A 20-year comparative study of Lepromatous vs. Tuberculoid Leprosy
PLOS Neglected Tropical Diseases: published June 26, 2026 | https://doi.org/10.1371/journal.pntd.0014385
Spatiotemporal differentiation of Plasmodium vivax populations in the western Greater Mekong Subregion using a 22-SNP barcode
PLOS Neglected Tropical Diseases: published June 29, 2026 | https://doi.org/10.1371/journal.pntd.0014472
Reinfection dynamics of owned dogs with Echinococcus granulosus sensu lato in endemic rural areas of central Iran: Implications for cystic echinococcosis control
PLOS Neglected Tropical Diseases: published June 29, 2026 | https://doi.org/10.1371/journal.pntd.0014451
The cobras (genus Naja) of Myanmar: An updated species list with information on identification, distributions, and medical importance
PLOS Neglected Tropical Diseases: published June 29, 2026 | https://doi.org/10.1371/journal.pntd.0014445
Prevalence, distribution, and phylogenetics of the tick-borne relapsing fever spirochete Borrelia turicatae in the soft tick Ornithodoros turicata americanus in Florida
PLOS Neglected Tropical Diseases: published June 29, 2026 | https://doi.org/10.1371/journal.pntd.0014473
Experimental evidence of early-phase transmission of Yersinia pestis by Synopsyllus fonquerniei and Xenopsylla brasiliensis
PLOS Neglected Tropical Diseases: published June 30, 2026 | https://doi.org/10.1371/journal.pntd.0014463
Implementing mass dog rabies vaccination through a community-based continuous approach: A socio-anthropological process evaluation
PLOS Neglected Tropical Diseases: published June 30, 2026 | https://doi.org/10.1371/journal.pntd.0014091
Diagnostic competence and health worker knowledge of female genital schistosomiasis management in a rural Ghanaian district
PLOS Neglected Tropical Diseases: published June 30, 2026 | https://doi.org/10.1371/journal.pntd.0013638
Corrections
Correction: Association of avian biodiversity and West Nile Virus circulation in Culex mosquitoes in Emilia-Romagna, Italy
PLOS Neglected Tropical Diseases: published June 2, 2026 | https://doi.org/10.1371/journal.pntd.0014400
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PLOS Neglected Tropical Diseases: published June 16, 2026 | https://doi.org/10.1371/journal.pntd.0014426
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