Florida Triatoma sanguisuga adult female (left) with 1st instar (top right) and 5th instar nymphal stages collected at a Florida home. Beatty & Bhosale et al, 2025
Image Credit: Nathan Burkett-Cadena
Viewpoints
Large language models and their performance for the diagnosis of histoplasmosis
PLOS Neglected Tropical Diseases: published July 9, 2025 | https://doi.org/10.1371/journal.pntd.0013151
Engaging communities in the control of arboviral diseases: insights from the African region
PLOS Neglected Tropical Diseases: published July 15, 2025 | https://doi.org/10.1371/journal.pntd.0013300
Country-level indices in predictive models of helminth infections: Perspectives from Southeast Asia
PLOS Neglected Tropical Diseases: published July 18, 2025 | https://doi.org/10.1371/journal.pntd.0013330
Cholera crisis persists: A call for integrated health strategies
PLOS Neglected Tropical Diseases: published July 23, 2025 | https://doi.org/10.1371/journal.pntd.0013272
Reviews
Trend analysis and spatiotemporal distribution of leishmaniasis disease incidence in Sri Lanka: A detailed review from 2009 to 2023
PLOS Neglected Tropical Diseases: published July 2, 2025 | https://doi.org/10.1371/journal.pntd.0013158
The emerging fungal pathogen Cryptococcus gattii: Epidemiology, pathogenesis, immunomodulatory attributes, and drug susceptibility
PLOS Neglected Tropical Diseases: published July 3, 2025 | https://doi.org/10.1371/journal.pntd.0013245
Comprehensive analysis of Toxoplasma gondii migration routes and tissue dissemination in the host
PLOS Neglected Tropical Diseases: published July 31, 2025 | https://doi.org/10.1371/journal.pntd.0013369
Research Articles
Safety and tolerability of metformin in overweight and obese patients with dengue: An open-label clinical trial (MeDO)
PLOS Neglected Tropical Diseases: published July 1, 2025 | https://doi.org/10.1371/journal.pntd.0013281
Assessment of the effectiveness of public art in improving knowledge, attitude, practices and mitigation of stigmatization regarding neglected tropical diseases in South Eastern, Nigeria
PLOS Neglected Tropical Diseases: published July 1, 2025 | https://doi.org/10.1371/journal.pntd.0013266
Tracking progress along the WHO Neglected Tropical Diseases Road Map to 2030: A guide to the Gap Assessment Tool (GAT) and results from the 2023–2024 assessment
PLOS Neglected Tropical Diseases: published July 1, 2025 | https://doi.org/10.1371/journal.pntd.0013194
Genetic structuring and estimation of reproductive adults in Onchocerca volvulus: A genome-wide analysis across hosts and regions
PLOS Neglected Tropical Diseases: published July 1, 2025 | https://doi.org/10.1371/journal.pntd.0013221
Effects of an integrated intervention on schistosomiasis prevalence in a rural area of Tanzania
PLOS Neglected Tropical Diseases: published July 2, 2025 | https://doi.org/10.1371/journal.pntd.0013215
Treatment outcomes of multi-drug-resistant and rifampicin-resistant tuberculosis with and without isolation of nontuberculous mycobacteria between 2018–2021: A retrospective cohort study in Ghana
PLOS Neglected Tropical Diseases: published July 2, 2025 | https://doi.org/10.1371/journal.pntd.0013204
Aedes aegypti ecology and dengue infection in three agricultural areas of Côte d’Ivoire
PLOS Neglected Tropical Diseases: published July 3, 2025 | https://doi.org/10.1371/journal.pntd.0013255
Genetic diversity of Murray Valley encephalitis virus 1951–2020 identified via phylogenetic and evolutionary analyses
PLOS Neglected Tropical Diseases: published July 3, 2025 | https://doi.org/10.1371/journal.pntd.0013181
Detecting soil-transmitted helminth and Schistosoma mansoni eggs in Kato-Katz stool smear microscopy images: A comprehensive in- and out-of-distribution evaluation of YOLOv7 variants
PLOS Neglected Tropical Diseases: published July 3, 2025 | https://doi.org/10.1371/journal.pntd.0013234
Optimizing dog population control strategies in Thailand using mathematical and economic modeling
PLOS Neglected Tropical Diseases: published July 3, 2025 | https://doi.org/10.1371/journal.pntd.0013202
Assessing the burden of Scorpionism: Epidemiological trends and health outcomes in Northwest of Iran
PLOS Neglected Tropical Diseases: published July 3, 2025 | https://doi.org/10.1371/journal.pntd.0013201
Brucellosis relapse: Rate, patient characteristics, and clinical outcomes in an endemic region
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0013270
Integrated vector management with the sterile insect technique component for the suppression of Aedes aegypti in an urban setting in Indonesia
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0013290
Cardiac alterations induced by Trypanosoma cruzi extracellular vesicles and immune complexes
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0013273
The frequency, clinical characteristics and outcomes of Naja species related injuries in Malaysia consulted to Remote Envenomation Consultancy Services from 2020–2023
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0013271
Associations between podoconiosis and pedogenic factors globally – A systematic review
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0013294
Field evidence of Trypanosoma cruzi infection, diverse host use and invasion of human dwellings by the Chagas disease vector in Florida, USA
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0012920
Schistosoma japonicum cathepsin L1: A potential target for anti-schistosomiasis strategies
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0013241
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A mixed-method study to improve outcome of mass drug administration in two TAS failed districts of Uttar Pradesh, India
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0013112
Antitrypanosomal therapy for Chagas disease: A single center experience with adverse drug reactions and strategies for enhancing treatment completion
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0013218
Target product profiles for new diagnostics to inform strongyloidiasis control programs
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0012774
Determining genotype and antimicrobial resistance of Salmonella Typhi in environmental samples by amplicon sequencing
PLOS Neglected Tropical Diseases: published July 8, 2025 | https://doi.org/10.1371/journal.pntd.0013211
Prevalence of Leishmania infection in refugee camps: A serological and molecular study in Gambella and Benishangul-Gumuz, Ethiopia
PLOS Neglected Tropical Diseases: published July 8, 2025 | https://doi.org/10.1371/journal.pntd.0013280
Functional characterization of a common XIa inhibitory Kunitz-domain Shp4 from nine schistosoma secreted proteins with diverse C-terminal fragments
PLOS Neglected Tropical Diseases: published July 8, 2025 | https://doi.org/10.1371/journal.pntd.0013282
Neurocysticercosis in Ecuador: Spatial clustering, social determinants, and epidemiological trends (2017–2023)
PLOS Neglected Tropical Diseases: published July 8, 2025 | https://doi.org/10.1371/journal.pntd.0012205
Forecasting high-risk areas for dengue outbreaks in China: A trend analysis of Aedes albopictus and Aedes aegypti distributions from 2014 to 2030
PLOS Neglected Tropical Diseases: published July 9, 2025 | https://doi.org/10.1371/journal.pntd.0013237
Benefits of public awareness in mitigating cystic echinococcosis risk in Western China: A climate and socio-economic perspective
PLOS Neglected Tropical Diseases: published July 9, 2025 | https://doi.org/10.1371/journal.pntd.0013182
Mapping the risk of Zika virus infections in pregnant persons and microcephaly in newborns in relation to socioeconomic indicators in Recife, Pernambuco, Brazil: A spatial analysis (2015 to 2021)
PLOS Neglected Tropical Diseases: published July 9, 2025 | https://doi.org/10.1371/journal.pntd.0013240
Zika virus-specific and orthoflavivirus-cross-reactive IgGs correlate with Zika virus seroneutralization depending on prior dengue virus infection
PLOS Neglected Tropical Diseases: published July 9, 2025 | https://doi.org/10.1371/journal.pntd.0013274
Estimating the incidence of dengue in international air travelers from non-endemic countries between 2010–2019
PLOS Neglected Tropical Diseases: published July 9, 2025 | https://doi.org/10.1371/journal.pntd.0013291
Vector control for Aedes aegypti and Aedes albopictus mosquitoes implemented in the field in sub-Saharan Africa: A scoping review
PLOS Neglected Tropical Diseases: published July 9, 2025 | https://doi.org/10.1371/journal.pntd.0013203
Healthcare workers’ priorities of WHO snakebite strategic objectives for the control and prevention of snakebite envenoming in Ghana: A machine learning statistical design of experiment modeling
PLOS Neglected Tropical Diseases: published July 10, 2025 | https://doi.org/10.1371/journal.pntd.0013295
Traditional medicine use among rabies exposed individuals in Ethiopia: A systematic review and meta-analysis
PLOS Neglected Tropical Diseases: published July 11, 2025 | https://doi.org/10.1371/journal.pntd.0013319
Suppression of Aedes aegypti by the sterile insect technique on Captiva Island, Florida, USA from 2020 to 2022
PLOS Neglected Tropical Diseases: published July 11, 2025 | https://doi.org/10.1371/journal.pntd.0013256
Reactive case detection can improve the efficiency of lymphatic filariasis surveillance compared to random sampling, Samoa 2023
PLOS Neglected Tropical Diseases: published July 11, 2025 | https://doi.org/10.1371/journal.pntd.0012622
Complexity of schistosome vector bulinine snails in Kenya: Insights from nuclear genome size variation, complete mitochondrial genome sequence, and morphometric analysis
PLOS Neglected Tropical Diseases: published July 14, 2025 | https://doi.org/10.1371/journal.pntd.0013305
Claustrophilic oviposition: Oviposition performance depends on container size in a novel forced oviposition method for Culex quinquefasciatus and Aedes aegypti
PLOS Neglected Tropical Diseases: published July 14, 2025 | https://doi.org/10.1371/journal.pntd.0013044
Genetic analysis of IFNG-AS1 implicates opposite effects to Leishmania guyanensis-cutaneous leishmaniasis: rs4913269 confers protection while rs7134599 enhances susceptibility and correlates with high plasma IL-4 and IL-10 levels
PLOS Neglected Tropical Diseases: published July 14, 2025 | https://doi.org/10.1371/journal.pntd.0013318
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Community perceptions of yellow fever and its treatment practices in regions with reported outbreaks in Uganda: A qualitative study
PLOS Neglected Tropical Diseases: published July 14, 2025 | https://doi.org/10.1371/journal.pntd.0013251
African strains of Zika virus resist ISG-mediated restriction
PLOS Neglected Tropical Diseases: published July 14, 2025 | https://doi.org/10.1371/journal.pntd.0013326
The m6A demethylase FTO regulates TNF-α expression in human macrophages following Toxoplasma gondii infection
PLOS Neglected Tropical Diseases: published July 15, 2025 | https://doi.org/10.1371/journal.pntd.0013289
High prevalence of Strongyloides stercoralis in people living with HIV: A critical health challenge in the Peruvian Amazon Basin
PLOS Neglected Tropical Diseases: published July 15, 2025 | https://doi.org/10.1371/journal.pntd.0013231
Large-scale epidemiology of opisthorchiasis in 21 provinces in Thailand based on diagnosis by fecal egg examination and urine antigen assay and analysis of risk factors for infection
PLOS Neglected Tropical Diseases: published July 16, 2025 | https://doi.org/10.1371/journal.pntd.0013095
Chikungunya in a pediatric cohort: Asymptomatic infection, seroconversion, and chronicity rates
PLOS Neglected Tropical Diseases: published July 16, 2025 | https://doi.org/10.1371/journal.pntd.0013254
Identifying key aspects to enhance predictive modeling for early identification of schistosomiasis hotspots to guide mass drug administration
PLOS Neglected Tropical Diseases: published July 16, 2025 | https://doi.org/10.1371/journal.pntd.0013315
Heterologous prime-boost immunization based on a human adenovirus 5 vectored containing Trichinella spiralis Cystatin-like protein elicits protective mucosal immunity in mice
PLOS Neglected Tropical Diseases: published July 16, 2025 | https://doi.org/10.1371/journal.pntd.0013323
Genetic shifts of Japanese encephalitis virus (JEV) in mosquitoes in the Republic of Korea, 2017–2022
PLOS Neglected Tropical Diseases: published July 17, 2025 | https://doi.org/10.1371/journal.pntd.0013258
Contributions of different host species to the natural transmission of severe fever with thrombocytopenia syndrome virus in China
PLOS Neglected Tropical Diseases: published July 17, 2025 | https://doi.org/10.1371/journal.pntd.0013304
Promising therapeutic efficacy of nitazoxanide-loaded zinc oxide nano-formula against intestinal and muscular phases of experimental trichinellosis
PLOS Neglected Tropical Diseases: published July 18, 2025 | https://doi.org/10.1371/journal.pntd.0013239
Enhanced rabies surveillance in roadkill specimens by real-time RT-PCR
PLOS Neglected Tropical Diseases: published July 18, 2025 | https://doi.org/10.1371/journal.pntd.0013348
Ultrasound screening for cystic echinococcosis of school-age children in endemic areas of Chile: A pilot cross-sectional study towards integration in the Regional Program for the Elimination of Cystic Echinococcosis 2020–2029
PLOS Neglected Tropical Diseases: published July 21, 2025 | https://doi.org/10.1371/journal.pntd.0013301
Cost-effectiveness of adding measurement of Chlamydia trachomatis infection and serology to trachoma prevalence surveys in Tanzania and Mozambique
PLOS Neglected Tropical Diseases: published July 21, 2025 | https://doi.org/10.1371/journal.pntd.0013257
Thrombocytopenia in patients with Plasmodium vivax in Colombia is associated with anti-phosphatidylserine autoantibodies and IL-6, IFNγ, IL-10 and TGF-β
PLOS Neglected Tropical Diseases: published July 21, 2025 | https://doi.org/10.1371/journal.pntd.0013284
Fascioliasis in north-central Vietnam: Assessing community knowledge, attitudes, and practices
PLOS Neglected Tropical Diseases: published July 21, 2025 | https://doi.org/10.1371/journal.pntd.0013324
Prevalence and risk factors associated with intestinal parasitosis in children with diarrhoea in the Huambo municipality
PLOS Neglected Tropical Diseases: published July 21, 2025 | https://doi.org/10.1371/journal.pntd.0013314
STAT1-mediated interferon signaling in the hematopoietic system is essential for restricting Usutu virus infection in vivo
PLOS Neglected Tropical Diseases: published July 22, 2025 | https://doi.org/10.1371/journal.pntd.0013317
Assessing Aedes mosquito larval indicators, dengue virus infection rates, and risk factors in Khyber Pakhtunkhwa: Insights for improved vector control strategies
PLOS Neglected Tropical Diseases: published July 22, 2025 | https://doi.org/10.1371/journal.pntd.0013252
Outbreak of cutaneous leishmaniasis amongst militia members in a non-endemic district under conflict in the lowlands of Somali Region caused by Leishmania tropica, Eastern Ethiopia
PLOS Neglected Tropical Diseases: published July 22, 2025 | https://doi.org/10.1371/journal.pntd.0013246
Prevalence, intensity, and associated factors of soil-transmitted helminth and schistosome infections after multiple rounds of preventive chemotherapy among schoolchildren in five selected district councils in Tanzania
PLOS Neglected Tropical Diseases: published July 23, 2025 | https://doi.org/10.1371/journal.pntd.0013310
An implementation science framework to understand low coverage in mass dog rabies vaccination
PLOS Neglected Tropical Diseases: published July 23, 2025 | https://doi.org/10.1371/journal.pntd.0012869
First isolation of viable Toxoplasma gondii from a black mangabey (Lophocebus aterrimus) reveals the emergence of the Africa 1 lineage in East Asia
PLOS Neglected Tropical Diseases: published July 23, 2025 | https://doi.org/10.1371/journal.pntd.0013133
A community-based vector control intervention “Slash and Clear” implemented in two onchocerciasis-endemic foci in South Sudan
PLOS Neglected Tropical Diseases: published July 23, 2025 | https://doi.org/10.1371/journal.pntd.0013309
Spatial occurrence-intensity modeling of dengue incidence in southernmost provinces of Thailand
PLOS Neglected Tropical Diseases: published July 23, 2025 | https://doi.org/10.1371/journal.pntd.0013347
The long-term persistence of the wMel strain in Rio de Janeiro is threatened by poor integrated vector management and bacterium fitness cost on Aedes aegypti
PLOS Neglected Tropical Diseases: published July 23, 2025 | https://doi.org/10.1371/journal.pntd.0013372
Association between hydrometeorological conditions and hemorrhagic fever with renal syndrome in Shandong Province, China, from 2005 to 2019
PLOS Neglected Tropical Diseases: published July 24, 2025 | https://doi.org/10.1371/journal.pntd.0013306
Development and evaluation of a triplex real-time PCR assay for enhanced plague diagnostics in Madagascar
PLOS Neglected Tropical Diseases: published July 24, 2025 | https://doi.org/10.1371/journal.pntd.0013278
Epidemiological characteristics of human-to-human transmission of severe fever with thrombocytopenia syndrome in China from 1996 to 2023
PLOS Neglected Tropical Diseases: published July 24, 2025 | https://doi.org/10.1371/journal.pntd.0013283
Knowledge, attitude, and practice (KAP), and acceptance and willingness to pay (WTP) for mosquito-borne diseases control through sterile mosquito release in Bangkok, Thailand
PLOS Neglected Tropical Diseases: published July 28, 2025 | https://doi.org/10.1371/journal.pntd.0011935
Precision mapping of schistosomiasis and soil-transmitted helminthiasis among school-age children: Targeting interventions in western Kenya
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Impact of weather extremes on the spatiotemporal dynamics of visceral leishmaniasis in Brazil
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Noncommunicable diseases associated with bleeding disorders, hospitalization, and mortality in patients with dengue in Mexico: A national analysis of confirmed cases in 2024
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High seroprevalence of antibodies to Dengue, Chikungunya, and Zika viruses in Dire Dawa, Ethiopia: A cross-sectional survey in 2024
PLOS Neglected Tropical Diseases: published July 28, 2025 | https://doi.org/10.1371/journal.pntd.0013357
Epidemiologic, clinical, and therapeutic aspects of formally identified Echis romani bites in northern Cameroon
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PLOS Neglected Tropical Diseases: published July 28, 2025 | https://doi.org/10.1371/journal.pntd.0013302
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PLOS Neglected Tropical Diseases: published July 28, 2025 | https://doi.org/10.1371/journal.pntd.0013356
Effectiveness and equity of vaccination strategies against Rift Valley fever in a heterogeneous landscape
PLOS Neglected Tropical Diseases: published July 28, 2025 | https://doi.org/10.1371/journal.pntd.0013346
Field responses of Glossina pallidipes and Glossina fuscipes fuscipes tsetse flies to Novel Repellent Blend and Waterbuck Repellent Compounds in Kenya
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Assessing the spatio-temporal risk of Aedes-borne arboviral diseases in non-endemic regions: The case of Northern Spain
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Comparative metabolism of conjugated and unconjugated pterins in Crithidia, Leishmania and African trypanosomes
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Computational screening of antiviral candidates for Monkeypox virus DNA polymerase and A42R protein
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Estimation of Lassa fever incidence rates in West Africa: Development of a modeling framework to inform vaccine trial design
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A rare case report of neuro-brucellosis with concurrence of depression, visual impairment, bilateral sensorineural hearing loss, and paraplegia
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LeishTec vaccination disrupts vertical transmission of Leishmania infantum
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Seasonal change of Burkholderia pseudomallei in paddy field water strongly correlates with ambient temperature: A study in north-central Vietnam
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Water, sanitation, and hygiene (WASH) factors and the incidence of communicable diseases in Urban Bangladesh: Evidence from municipal areas
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A comprehensive murine clinical model for development of countermeasures and studying Mayaro virus infection
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Unveiling the cardiovascular impact of Zika Virus: Myocardial injury, prothrombotic state, and oxidative stress in immunocompetent mice
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Psychological distress, perceived stress, and public stigma in skin neglected tropical diseases in Ghana: A structural equation model of a cross-sectional survey
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MaxEnt modeling and risk evaluation of chagas disease vectors in the domestic cycle of Hidalgo, Mexico
PLOS Neglected Tropical Diseases: published July 31, 2025 | https://doi.org/10.1371/journal.pntd.0013199
Corrections
Correction: An oral recombinant vaccine in dogs against Echinococcus granulosus, the causative agent of human hydatid disease: A pilot study
PLOS Neglected Tropical Diseases: published July 1, 2025 | https://doi.org/10.1371/journal.pntd.0013238
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Formal Comments
Response to comment on: [Potential bias in the analysis of prenatal treatment for congenital toxoplasmosis]
PLOS Neglected Tropical Diseases: published July 7, 2025 | https://doi.org/10.1371/journal.pntd.0013138
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