October 2018

Sampling processes were included in an entomological survey which was conducted in urban and rural settings of Southern Taiwan. The objective of the survey was to assess for distinct predictors (location, season, and function) of Ae. aegypti juveniles (1st - 4th instar larvae and pupae) and pupae numbers, respectively, in water holding containers found in residential and non-residential areas, 2013 - 2015. Lin, et al. (2018)

Image Credit: Karin Linda Schiøler

Editorial

Catalyzing NTD gender and equity research: A call for papers

Arianna Rubin Means, Alison Krentel, Sally Theobald, Laura Dean, Pamela Sabina Mbabazi, Thoko Elphick-Pooley, Fiona M. Fleming, Julie Jacobson, Sarah Simpson, Camilla Ducker

PLOS Neglected Tropical Diseases: published October 18, 2018 | https://doi.org/10.1371/journal.pntd.0006681

Viewpoints

Can sequential aerosol technique be used against riverine tsetse?

Reginald De Deken, Jérémy Bouyer

PLOS Neglected Tropical Diseases: published October 11, 2018 | https://doi.org/10.1371/journal.pntd.0006768

Pakistan: A nation held back by NTDs

Alexander J. Blum, M. Farhan Majid, Peter J. Hotez

PLOS Neglected Tropical Diseases: published October 18, 2018 | https://doi.org/10.1371/journal.pntd.0006751

Advanced surveillance and preparedness to meet a new era of invasive vectors and emerging vector-borne diseases

Rebekah C. Kading, Andrew J. Golnar, Sarah A. Hamer, Gabriel L. Hamer

PLOS Neglected Tropical Diseases: published October 25, 2018 | https://doi.org/10.1371/journal.pntd.0006761

Policy Platform

From recognition to action: A strategic approach to foster sustainable collaborations for rabies elimination

Rany Octaria, Stephanie J. Salyer, Jesse Blanton, Emily G. Pieracci, Peninah Munyua, Max Millien, Louis Nel, Ryan M. Wallace

PLOS Neglected Tropical Diseases: published October 25, 2018 | https://doi.org/10.1371/journal.pntd.0006756

Symposium

A rare case of visceral leishmaniasis in an immunocompetent traveler returning to the United States from Europe

Lamia Haque, Merceditas Villanueva, Armand Russo, Youzhong Yuan, Eun-Ju Lee, Jeffrey Topal, Nikolai Podoltsev

PLOS Neglected Tropical Diseases: published October 4, 2018 | https://doi.org/10.1371/journal.pntd.0006727

Research Articles

Quantification of dengue virus specific T cell responses and correlation with viral load and clinical disease severity in acute dengue infection

Dulharie T. Wijeratne, Samitha Fernando, Laksiri Gomes, Chandima Jeewandara, Anushka Ginneliya, Supun Samarasekara, Ananda Wijewickrama, Clare S. Hardman, Graham S. Ogg, Gathsaurie Neelika Malavige

PLOS Neglected Tropical Diseases: published October 1, 2018 | https://doi.org/10.1371/journal.pntd.0006540

Use of structural equation models to predict dengue illness phenotype

Sangshin Park, Anon Srikiatkhachorn, Siripen Kalayanarooj, Louis Macareo, Sharone Green, Jennifer F. Friedman, Alan L. Rothman

PLOS Neglected Tropical Diseases: published October 1, 2018 | https://doi.org/10.1371/journal.pntd.0006799

STLV-1 co-infection is correlated with an increased SFV proviral load in the peripheral blood of SFV/STLV-1 naturally infected non-human primates

Sandrine Alais, Amandine Pasquier, Brice Jegado, Chloé Journo, Réjane Rua, Antoine Gessain, Joelle Tobaly-Tapiero, Romain Lacoste, Jocelyn Turpin, Renaud Mahieux

PLOS Neglected Tropical Diseases: published October 1, 2018 | https://doi.org/10.1371/journal.pntd.0006812

Bile acids drive chemotaxis of Clonorchis sinensis juveniles to the bile duct

Shunyu Li, Won Gi Yoo, Jin-Ho Song, Tae Im Kim, Sung-Jong Hong

PLOS Neglected Tropical Diseases: published October 1, 2018 | https://doi.org/10.1371/journal.pntd.0006818

Knowledge, attitudes and practices about human African trypanosomiasis and their implications in designing intervention strategies for Yei county, South Sudan

Salome A. Bukachi, Angeline A. Mumbo, Ayak C. D. Alak, Wilson Sebit, John Rumunu, Sylvain Biéler, Joseph M. Ndung'u

PLOS Neglected Tropical Diseases: published October 1, 2018 | https://doi.org/10.1371/journal.pntd.0006826

Stress susceptibility in Trypanosoma brucei lacking the RNA-binding protein ZC3H30

Chaitali Chakraborty, Christine Clayton

PLOS Neglected Tropical Diseases: published October 1, 2018 | https://doi.org/10.1371/journal.pntd.0006835

Indoor residual spraying for kala-azar vector control in Bangladesh: A continuing challenge

Rajib Chowdhury, Vashkar Chowdhury, Shyla Faria, Saiful Islam, Narayan Prosad Maheswary, Shireen Akhter, Md. Sahidul Islam, Aditya Prasad Dash, Axel Kroeger, Qamar Banu

PLOS Neglected Tropical Diseases: published October 1, 2018 | https://doi.org/10.1371/journal.pntd.0006846

Defining stopping criteria for ending randomized clinical trials that investigate the interruption of transmission of soil-transmitted helminths employing mass drug administration

Marleen Werkman, Jaspreet Toor, Carolin Vegvari, James E. Wright, James E. Truscott, Kristjana H. Ásbjörnsdóttir, Arianna Rubin Means, Judd L. Walson, Roy M. Anderson

PLOS Neglected Tropical Diseases: published October 1, 2018 | https://doi.org/10.1371/journal.pntd.0006864

Leprosy in children under 15 years of age in Brazil: A systematic review of the literature

Michelle Christini Araújo Vieira, Joilda Silva Nery, Enny S. Paixão, Kaio Vinicius Freitas de Andrade, Gerson Oliveira Penna, Maria Glória Teixeira

PLOS Neglected Tropical Diseases: published October 2, 2018 | https://doi.org/10.1371/journal.pntd.0006788

Beating the odds: Sustained Chagas disease vector control in remote indigenous communities of the Argentine Chaco over a seven-year period

M. Sol Gaspe, Yael M. Provecho, María P. Fernández, Claudia V. Vassena, Pablo L. Santo Orihuela, Ricardo E. Gürtler

PLOS Neglected Tropical Diseases: published October 2, 2018 | https://doi.org/10.1371/journal.pntd.0006804

Typhoid fever outbreak in the Democratic Republic of Congo: Case control and ecological study

Julii Brainard, Rob D’hondt, Engy Ali, Rafael Van den Bergh, Anja De Weggheleire, Yves Baudot, Frederic Patigny, Vincent Lambert, Rony Zachariah, Peter Maes, Donat Kuma-Kuma Kenge, Paul R. Hunter

PLOS Neglected Tropical Diseases: published October 3, 2018 | https://doi.org/10.1371/journal.pntd.0006795

Development of standard clinical endpoints for use in dengue interventional trials

Kay M. Tomashek, Bridget Wills, Lucy Chai See Lum, Laurent Thomas, Anna Durbin, Yee-Sin Leo, Norma de Bosch, Elsa Rojas, Kim Hendrickx, Martin Erpicum, Liane Agulto, Thomas Jaenisch, Hasitha Tissera, Piyarat Suntarattiwong, Beth Ann Collers, Derek Wallace, Alexander C. Schmidt, Alexander Precioso, Federico Narvaez, Stephen J. Thomas, Robert Edelman, João Bosco Siqueira, M. Cristina Cassetti, Walla Dempsey, Duane J. Gubler

PLOS Neglected Tropical Diseases: published October 4, 2018 | https://doi.org/10.1371/journal.pntd.0006497

Dengue illness index—A tool to characterize the subjective dengue illness experience

Stephen J. Thomas, Liane Agulto, Kim Hendrickx, Martin Erpicum, Kay M. Tomashek, M. Cristina Cassetti, Catherine Laughlin, Alexander Precioso, Alexander C. Schmidt, Federico Narvaez, João Bosco Siqueira, Hasitha Tissera, Robert Edelman

PLOS Neglected Tropical Diseases: published October 4, 2018 | https://doi.org/10.1371/journal.pntd.0006593

Engineered nanoparticles bind elapid snake venom toxins and inhibit venom-induced dermonecrosis

Jeffrey O’Brien, Shih-Hui Lee, José María Gutiérrez, Kenneth J. Shea

PLOS Neglected Tropical Diseases: published October 4, 2018 | https://doi.org/10.1371/journal.pntd.0006736

Population genetic analysis of Chadian Guinea worms reveals that human and non-human hosts share common parasite populations

Elizabeth A. Thiele, Mark L. Eberhard, James A. Cotton, Caroline Durrant, Jeffrey Berg, Kelsey Hamm, Ernesto Ruiz-Tiben

PLOS Neglected Tropical Diseases: published October 4, 2018 | https://doi.org/10.1371/journal.pntd.0006747

Community-based prevalence of typhoid fever, typhus, brucellosis and malaria among symptomatic individuals in Afar Region, Ethiopia

Biruk Zerfu, Girmay Medhin, Gezahegne Mamo, Gezahegn Getahun, Rea Tschopp, Mengistu Legesse

PLOS Neglected Tropical Diseases: published October 4, 2018 | https://doi.org/10.1371/journal.pntd.0006749

Inter- and intra-host sequence diversity reveal the emergence of viral variants during an overwintering epidemic caused by dengue virus serotype 2 in southern Taiwan

Hui-Ying Ko, Yao-Tsun Li, Day-Yu Chao, Yun-Cheng Chang, Zheng-Rong T. Li, Melody Wang, Chuan-Liang Kao, Tzai-Hung Wen, Pei-Yun Shu, Gwong-Jen J. Chang, Chwan-Chuen King

PLOS Neglected Tropical Diseases: published October 4, 2018 | https://doi.org/10.1371/journal.pntd.0006827

The role of case proximity in transmission of visceral leishmaniasis in a highly endemic village in Bangladesh

Lloyd A. C. Chapman, Chris P. Jewell, Simon E. F. Spencer, Lorenzo Pellis, Samik Datta, Rajib Chowdhury, Caryn Bern, Graham F. Medley, T. Déirdre Hollingsworth

PLOS Neglected Tropical Diseases: published October 8, 2018 | https://doi.org/10.1371/journal.pntd.0006453

Identifying a sufficient core group for trachoma transmission

Thomas M. Lietman, Michael S. Deiner, Catherine E. Oldenburg, Scott D. Nash, Jeremy D. Keenan, Travis C. Porco

PLOS Neglected Tropical Diseases: published October 8, 2018 | https://doi.org/10.1371/journal.pntd.0006478

The effect of assortative mixing on stability of low helminth transmission levels and on the impact of mass drug administration: Model explorations for onchocerciasis

Anneke S. de Vos, Wilma A. Stolk, Sake J. de Vlas, Luc E. Coffeng

PLOS Neglected Tropical Diseases: published October 8, 2018 | https://doi.org/10.1371/journal.pntd.0006624

Quantifying the value of surveillance data for improving model predictions of lymphatic filariasis elimination

Edwin Michael, Swarnali Sharma, Morgan E. Smith, Panayiota Touloupou, Federica Giardina, Joaquin M. Prada, Wilma A. Stolk, Deirdre Hollingsworth, Sake J. de Vlas

PLOS Neglected Tropical Diseases: published October 8, 2018 | https://doi.org/10.1371/journal.pntd.0006674

The design of schistosomiasis monitoring and evaluation programmes: The importance of collecting adult data to inform treatment strategies for Schistosoma mansoni

Jaspreet Toor, Hugo C. Turner, James E. Truscott, Marleen Werkman, Anna E. Phillips, Ramzi Alsallaq, Graham F. Medley, Charles H. King, Roy M. Anderson

PLOS Neglected Tropical Diseases: published October 8, 2018 | https://doi.org/10.1371/journal.pntd.0006717

Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils

Bin Zhan, Sridhar Arumugam, Malcolm W. Kennedy, Nancy Tricoche, Lu-Yun Lian, Oluwatoyin A. Asojo, Sasisekhar Bennuru, Maria Elena Bottazzi, Peter J. Hotez, Sara Lustigman, Thomas R. Klei

PLOS Neglected Tropical Diseases: published October 8, 2018 | https://doi.org/10.1371/journal.pntd.0006772

The impact and cost-effectiveness of controlling cholera through the use of oral cholera vaccines in urban Bangladesh: A disease modeling and economic analysis

Ashraful Islam Khan, Ann Levin, Dennis L. Chao, Denise DeRoeck, Dobromir T. Dimitrov, Jahangir A. M. Khan, Muhammad Shariful Islam, Mohammad Ali, Md. Taufiqul Islam, Abdur Razzaque Sarker, John D. Clemens, Firdausi Qadri

PLOS Neglected Tropical Diseases: published October 9, 2018 | https://doi.org/10.1371/journal.pntd.0006652

Intrinsic activation of the vitamin D antimicrobial pathway by M. leprae infection is inhibited by type I IFN

Kathryn Zavala, Carter A. Gottlieb, Rosane M. Teles, John S. Adams, Martin Hewison, Robert L. Modlin, Philip T. Liu

PLOS Neglected Tropical Diseases: published October 9, 2018 | https://doi.org/10.1371/journal.pntd.0006815

Transcriptomic and functional analyses of the piRNA pathway in the Chagas disease vector Rhodnius prolixus

Tarcisio Brito, Alison Julio, Mateus Berni, Lisiane de Castro Poncio, Emerson Soares Bernardes, Helena Araujo, Michael Sammeth, Attilio Pane

PLOS Neglected Tropical Diseases: published October 10, 2018 | https://doi.org/10.1371/journal.pntd.0006760

Complete genome sequences of two strains of Treponema pallidum subsp. pertenue from Indonesia: Modular structure of several treponemal genes

Michal Strouhal, Lenka Mikalová, Jan Haviernik, Sascha Knauf, Sylvia Bruisten, Gerda T. Noordhoek, Jan Oppelt, Darina Čejková, David Šmajs

PLOS Neglected Tropical Diseases: published October 10, 2018 | https://doi.org/10.1371/journal.pntd.0006867

Optimising sampling regimes and data collection to inform surveillance for trachoma control

Amy Pinsent, T. Dèirdre Hollingsworth

PLOS Neglected Tropical Diseases: published October 11, 2018 | https://doi.org/10.1371/journal.pntd.0006531

Rutin (quercetin-3-rutinoside) modulates the hemostatic disturbances and redox imbalance induced by Bothrops jararaca snake venom in mice

Ana Teresa Azevedo Sachetto, Jaqueline Gomes Rosa, Marcelo Larami Santoro

PLOS Neglected Tropical Diseases: published October 11, 2018 | https://doi.org/10.1371/journal.pntd.0006774

A systematic review of antimicrobial resistance in Salmonella enterica serovar Typhi, the etiological agent of typhoid

Carl D. Britto, Vanessa K. Wong, Gordan Dougan, Andrew J. Pollard

PLOS Neglected Tropical Diseases: published October 11, 2018 | https://doi.org/10.1371/journal.pntd.0006779

Predictive risk mapping of an environmentally-driven infectious disease using spatial Bayesian networks: A case study of leptospirosis in Fiji

Helen J. Mayfield, Carl S. Smith, John H. Lowry, Conall H. Watson, Michael G. Baker, Mike Kama, Eric J. Nilles, Colleen L. Lau

PLOS Neglected Tropical Diseases: published October 11, 2018 | https://doi.org/10.1371/journal.pntd.0006857

A gene expression comparison of Trypanosoma brucei and Trypanosoma congolense in the bloodstream of the mammalian host reveals species-specific adaptations to density-dependent development

Eleanor Silvester, Alasdair Ivens, Keith R. Matthews

PLOS Neglected Tropical Diseases: published October 11, 2018 | https://doi.org/10.1371/journal.pntd.0006863

Estimating the economic impact of canine rabies to Viet Nam 2005–2014

Stephanie A. Shwiff, Vienna R. Brown, Thu Trang Dao, Julie Elser, Hoang Xuan Trung, Nguyen Ngoc Tien, Nguyen Thi Huong, Nguyen Thi Thanh Huong, Arthorn Riewpaiboon, Karina Ernst, Steven Shwiff, David Payne

PLOS Neglected Tropical Diseases: published October 11, 2018 | https://doi.org/10.1371/journal.pntd.0006866

Risk factors for HTLV-1 infection in Central Africa: A rural population-based survey in Gabon

Delia Doreen Djuicy, Augustin Mouinga-Ondémé, Olivier Cassar, Jill-Léa Ramassamy, Antony Idam Mamimandjiami, Rodrigue Bikangui, Arnaud Fontanet, Antoine Gessain

PLOS Neglected Tropical Diseases: published October 12, 2018 | https://doi.org/10.1371/journal.pntd.0006832

Modification and optimization of the FECPAK^G2 protocol for the detection and quantification of soil-transmitted helminth eggs in human stool

Mio Ayana, Johnny Vlaminck, Piet Cools, Shaali Ame, Marco Albonico, Daniel Dana, Jennifer Keiser, Helen Manly, Leonardo F. Matoso, Zeleke Mekonnen, Antonio Montresor, Rodrigo Correa-Oliveira, Laura Rinaldi, Somphou Sayasone, Stephen Sowersby, Lensa Tesfaye, Jozef Vercruysse, Greg Mirams, Bruno Levecke

PLOS Neglected Tropical Diseases: published October 15, 2018 | https://doi.org/10.1371/journal.pntd.0006655

Vector competence of Aedes bromeliae and Aedes vitattus mosquito populations from Kenya for chikungunya virus

Francis Mulwa, Joel Lutomiah, Edith Chepkorir, Samwel Okello, Fredrick Eyase, Caroline Tigoi, Michael Kahato, Rosemary Sang

PLOS Neglected Tropical Diseases: published October 15, 2018 | https://doi.org/10.1371/journal.pntd.0006746

Location, seasonal, and functional characteristics of water holding containers with juvenile and pupal Aedes aegypti in Southern Taiwan: A cross-sectional study using hurdle model analyses

Chia-Hsien Lin, Karin Linda Schiøler, Claus Thorn Ekstrøm, Flemming Konradsen

PLOS Neglected Tropical Diseases: published October 15, 2018 | https://doi.org/10.1371/journal.pntd.0006882

Development of an urban molecular xenomonitoring system for lymphatic filariasis in the Recife Metropolitan Region, Brazil

Anita Ramesh, Mary Cameron, Kirstin Spence, Remy Hoek Spaans, Maria A. V. Melo-Santos, Marcelo H. S. Paiva, Duschinka R. D. Guedes, Rosangela M. R. Barbosa, Claudia M. F. Oliveira, André Sá, Claire L. Jeffries, Priscila M. S. Castanha, Paula A. S. Oliveira, Thomas Walker, Neal Alexander, Cynthia Braga

PLOS Neglected Tropical Diseases: published October 16, 2018 | https://doi.org/10.1371/journal.pntd.0006816

Effect of schistosomiasis on the outcome of patients infected with HIV-1 starting antiretroviral therapy in rural Tanzania

Katarina Stete, Tracy R. Glass, Govert J. van Dam, Alex Ntamatungiro, Emilio Letang, Claudia J. de Dood, Paul L. A. M. Corstjens, Robert Ndege, Herry Mapesi, Winfried V. Kern, Christoph Hatz, Maja Weisser, Jürg Utzinger, Matthias C. Müller

PLOS Neglected Tropical Diseases: published October 17, 2018 | https://doi.org/10.1371/journal.pntd.0006844

Safety, efficacy and acceptability of praziquantel in the treatment of Schistosoma haematobium in pre-school children of Kwale County, Kenya

Bridget W. Kimani, Amos K. Mbugua, Jimmy H. Kihara, Murima Ng’ang’a, Doris W. Njomo

PLOS Neglected Tropical Diseases: published October 17, 2018 | https://doi.org/10.1371/journal.pntd.0006852

What motivates Ebola survivors to donate plasma during an emergency clinical trial? The case of Ebola-Tx in Guinea

Maya Ronse, Almudena Marí Sáez, Charlotte Gryseels, Melanie Bannister-Tyrrell, Alexandre Delamou, Alain Guillard, Mustapha Briki, Frédéric Bigey, Nyankoye Haba, Johan van Griensven, Koen Peeters Grietens

PLOS Neglected Tropical Diseases: published October 17, 2018 | https://doi.org/10.1371/journal.pntd.0006885

Uncovering vector, parasite, blood meal and microbiome patterns from mixed-DNA specimens of the Chagas disease vector Triatoma dimidiata

Lucia C. Orantes, Carlota Monroy, Patricia L. Dorn, Lori Stevens, Donna M. Rizzo, Leslie Morrissey, John P. Hanley, Antonieta Guadalupe Rodas, Bethany Richards, Kimberly F. Wallin, Sara Helms Cahan

PLOS Neglected Tropical Diseases: published October 18, 2018 | https://doi.org/10.1371/journal.pntd.0006730

A MALDI-TOF MS database with broad genus coverage for species-level identification of Brucella

Jennifer Mesureur, Sandrine Arend, Béatrice Cellière, Priscillia Courault, Pierre-Jean Cotte-Pattat, Heather Totty, Parampal Deol, Virginie Mick, Victoria Girard, Joanne Touchberry, Vanessa Burrowes, Jean-Philippe Lavigne, David O’Callaghan, Valérie Monnin, Anne Keriel

PLOS Neglected Tropical Diseases: published October 18, 2018 | https://doi.org/10.1371/journal.pntd.0006874

Histoplasma capsulatum antigen detection tests as an essential diagnostic tool for patients with advanced HIV disease in low and middle income countries: A systematic review of diagnostic accuracy studies

Mathieu Nacher, Denis Blanchet, Felix Bongomin, Arunaloke Chakrabarti, Pierre Couppié, Magalie Demar, David W. Denning, Félix Djossou, Loïc Epelboin, Nelesh Govender, Terezinha Leitão, Sigrid Mac Donald, Christine Mandengue, Silvia Helena Marques da Silva, Rita Oladele, Maria Mercedes Panizo, Alessandro Pasqualotto, Ruth Ramos, Subramanian Swaminathan, Juan Luis Rodriguez-Tudela, Stephen Vreden, Rosely Zancopé-Oliveira, Antoine Adenis

PLOS Neglected Tropical Diseases: published October 19, 2018 | https://doi.org/10.1371/journal.pntd.0006802

Genetic diversity in two Plasmodium vivax protein ligands for reticulocyte invasion

Camille Roesch, Jean Popovici, Sophalai Bin, Vorleak Run, Saorin Kim, Stéphanie Ramboarina, Emma Rakotomalala, Rado Lalaina Rakotoarison, Tsikiniaina Rasoloharimanana, Zo Andriamanantena, Anuj Kumar, Micheline Guillotte-Blisnick, Christèle Huon, David Serre, Chetan E. Chitnis, Inès Vigan-Womas, Didier Menard

PLOS Neglected Tropical Diseases: published October 22, 2018 | https://doi.org/10.1371/journal.pntd.0006555

Field safety and effectiveness of new visceral leishmaniasis treatment regimens within public health facilities in Bihar, India

Vishal Goyal, Raman Mahajan, Krishna Pandey, Shambhu Nath Singh, Ravi Shankar Singh, Nathalie Strub-Wourgaft, Fabiana Alves, Vidya Nand Rabi Das, Roshan Kamal Topno, Bhawna Sharma, Manica Balasegaram, Caryn Bern, Allen Hightower, Suman Rijal, Sally Ellis, Temmy Sunyoto, Sakib Burza, Nines Lima, Pradeep Das, Jorge Alvar

PLOS Neglected Tropical Diseases: published October 22, 2018 | https://doi.org/10.1371/journal.pntd.0006830

Distinct monocyte subset phenotypes in patients with different clinical forms of chronic Chagas disease and seronegative dilated cardiomyopathy

Damián E. Pérez-Mazliah, Melisa D. Castro Eiro, María Gabriela Álvarez, Bruno Lococo, Graciela Bertocchi, Gonzalo César, María A. Natale, María C. Albareda, Rodolfo Viotti, Susana A. Laucella

PLOS Neglected Tropical Diseases: published October 22, 2018 | https://doi.org/10.1371/journal.pntd.0006887

Efficacy comparison between long-term high-dose praziquantel and surgical therapy for cerebral sparganosis: A multicenter retrospective cohort study

Daojun Hong, Huiqun Xie, Hui Wan, Ning An, Chunhua Xu, Jun Zhang

PLOS Neglected Tropical Diseases: published October 22, 2018 | https://doi.org/10.1371/journal.pntd.0006918

Update on the current status of onchocerciasis in Côte d’Ivoire following 40 years of intervention: Progress and challenges

Benjamin G. Koudou, Marie-Madeleine Kouakou, Allassane F. Ouattara, Souleymane Yeo, Pierre Brika, Aboulaye Meite, Elvis Aba, Christopher L. King, Roger Kouakou, Gary J. Weil, Peter U. Fischer

PLOS Neglected Tropical Diseases: published October 23, 2018 | https://doi.org/10.1371/journal.pntd.0006897

Quantification of permethrin resistance and kdr alleles in Florida strains of Aedes aegypti (L.) and Aedes albopictus (Skuse)

Alden S. Estep, Neil D. Sanscrainte, Christy M. Waits, Sarah J. Bernard, Aaron M. Lloyd, Keira J. Lucas, Eva A. Buckner, Rajeev Vaidyanathan, Rachel Morreale, Lisa A. Conti, James J. Becnel

PLOS Neglected Tropical Diseases: published October 24, 2018 | https://doi.org/10.1371/journal.pntd.0006544

ICR suckling mouse model of Zika virus infection for disease modeling and drug validation

Yu-Hsuan Wu, Chin-Kai Tseng, Chun-Kuang Lin, Chih-Ku Wei, Jin-Ching Lee, Kung-Chia Young

PLOS Neglected Tropical Diseases: published October 24, 2018 | https://doi.org/10.1371/journal.pntd.0006848

Viridot: An automated virus plaque (immunofocus) counter for the measurement of serological neutralizing responses with application to dengue virus

Leah C. Katzelnick, Ana Coello Escoto, Benjamin D. McElvany, Christian Chávez, Henrik Salje, Wensheng Luo, Isabel Rodriguez-Barraquer, Richard Jarman, Anna P. Durbin, Sean A. Diehl, Derek J. Smith, Stephen S. Whitehead, Derek A. T. Cummings

PLOS Neglected Tropical Diseases: published October 24, 2018 | https://doi.org/10.1371/journal.pntd.0006862

Seroprevalence of dengue virus in two districts of Kaohsiung City after the largest dengue outbreak in Taiwan since World War II

Jih-Jin Tsai, Ching-Kuan Liu, Wen-Yang Tsai, Li-Teh Liu, Jasmine Tyson, Ching-Yi Tsai, Ping-Chang Lin, Wei-Kung Wang

PLOS Neglected Tropical Diseases: published October 24, 2018 | https://doi.org/10.1371/journal.pntd.0006879

Spatial heterogeneity of hemorrhagic fever with renal syndrome is driven by environmental factors and rodent community composition

Hong Xiao, Xin Tong, Lidong Gao, Shixiong Hu, Hua Tan, Zheng Y. X. Huang, Guogang Zhang, Qiqi Yang, Xinyao Li, Ru Huang, Shilu Tong, Huaiyu Tian

PLOS Neglected Tropical Diseases: published October 24, 2018 | https://doi.org/10.1371/journal.pntd.0006881

The recently identified flavivirus Bamaga virus is transmitted horizontally by Culex mosquitoes and interferes with West Nile virus replication in vitro and transmission in vivo

Agathe M. G. Colmant, Sonja Hall-Mendelin, Scott A. Ritchie, Helle Bielefeldt-Ohmann, Jessica J. Harrison, Natalee D. Newton, Caitlin A. O’Brien, Chris Cazier, Cheryl A. Johansen, Jody Hobson-Peters, Roy A. Hall, Andrew F. van den Hurk

PLOS Neglected Tropical Diseases: published October 24, 2018 | https://doi.org/10.1371/journal.pntd.0006886

Knowledge, attitude and practices of snakebite management amongst health workers in Cameroon: Need for continuous training and capacity building

Fabien Taieb, Timothée Dub, Yoann Madec, Laura Tondeur, Jean Philippe Chippaux, Matthew Lebreton, Raphael Medang, Françoise Ngnedjou Nwabufo Foute, Désiré Tchoffo, Julien Potet, Gabriel Alcoba, Eric Comte, Ellen M. Einterz, Armand S. Nkwescheu

PLOS Neglected Tropical Diseases: published October 25, 2018 | https://doi.org/10.1371/journal.pntd.0006716

SIV/SHIV-Zika co-infection does not alter disease pathogenesis in adult non-pregnant rhesus macaque model

Mehdi R. M. Bidokhti, Debashis Dutta, Lepakshe S. V. Madduri, Shawna M. Woollard, Robert Norgren Jr., Luis Giavedoni, Siddappa N. Byrareddy

PLOS Neglected Tropical Diseases: published October 25, 2018 | https://doi.org/10.1371/journal.pntd.0006811

Revisiting human T-cell lymphotropic virus types 1 and 2 infections among rural population in Gabon, central Africa thirty years after the first analysis

Melanie Caron, Guillaume Besson, Cindy Padilla, Maria Makuwa, Dieudonne Nkoghe, Eric Leroy, Mirdad Kazanji

PLOS Neglected Tropical Diseases: published October 25, 2018 | https://doi.org/10.1371/journal.pntd.0006833

Uncharted territory of the epidemiological burden of cutaneous leishmaniasis in sub-Saharan Africa—A systematic review

Temmy Sunyoto, Kristien Verdonck, Sayda el Safi, Julien Potet, Albert Picado, Marleen Boelaert

PLOS Neglected Tropical Diseases: published October 25, 2018 | https://doi.org/10.1371/journal.pntd.0006914

High accuracy of an ELISA test based in a flagella antigen of Leishmania in serodiagnosis of canine visceral leishmaniasis with potential to improve the control measures in Brazil – A Phase II study

Lairton Souza Borja, Lívia Brito Coelho, Matheus Silva de Jesus, Artur Trancoso Lopo de Queiroz, Paola Alejandra Fiorani Celedon, Nilson Ivo Tonin Zachin, Edimilson Domingos Silva, Antônio Gomes Pinto Ferreira, Marco Aurélio Krieger, Patrícia Sampaio Tavares Veras, Deborah Bittencourt Mothé Fraga

PLOS Neglected Tropical Diseases: published October 26, 2018 | https://doi.org/10.1371/journal.pntd.0006871

Inhibition of histone methyltransferase EZH2 in Schistosoma mansoni in vitro by GSK343 reduces egg laying and decreases the expression of genes implicated in DNA replication and noncoding RNA metabolism

Adriana S. A. Pereira, Murilo S. Amaral, Elton J. R. Vasconcelos, David S. Pires, Huma Asif, Lucas F. daSilva, David A. Morales-Vicente, Vitor C. Carneiro, Claudia B. Angeli, Giuseppe Palmisano, Marcelo R. Fantappie, Raymond J. Pierce, João C. Setubal, Sergio Verjovski-Almeida

PLOS Neglected Tropical Diseases: published October 26, 2018 | https://doi.org/10.1371/journal.pntd.0006873

Spatial prediction of risk areas for vector transmission of Trypanosoma cruzi in the State of Paraná, southern Brazil

Andréia Mantovani Ferro e Silva, Thadeu Sobral-Souza, Maurício Humberto Vancine, Renata Lara Muylaert, Ana Paula de Abreu, Sandra Marisa Pelloso, Maria Dalva de Barros Carvalho, Luciano de Andrade, Milton Cezar Ribeiro, Max Jean de Ornelas Toledo

PLOS Neglected Tropical Diseases: published October 26, 2018 | https://doi.org/10.1371/journal.pntd.0006907

Spatial-temporal clustering analysis of yaws on Lihir Island, Papua New Guinea to enhance planning and implementation of eradication programs

Eric Q. Mooring, Oriol Mitjà, Megan B. Murray

PLOS Neglected Tropical Diseases: published October 29, 2018 | https://doi.org/10.1371/journal.pntd.0006840

Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography

Patricia de Aguiar Amaral, Delphine Autheman, Guilherme Dias de Melo, Nicolas Gouault, Jean-François Cupif, Sophie Goyard, Patricia Dutra, Nicolas Coatnoan, Alain Cosson, Damien Monet, Frederick Saul, Ahmed Haouz, Philippe Uriac, Arnaud Blondel, Paola Minoprio

PLOS Neglected Tropical Diseases: published October 29, 2018 | https://doi.org/10.1371/journal.pntd.0006853

A simian-adenovirus-vectored rabies vaccine suitable for thermostabilisation and clinical development for low-cost single-dose pre-exposure prophylaxis

Chuan Wang, Pawan Dulal, Xiangyang Zhou, Zhiquan Xiang, Hooman Goharriz, Ashley Banyard, Nicky Green, Livia Brunner, Roland Ventura, Nicolas Collin, Simon J. Draper, Adrian V. S. Hill, Rebecca Ashfield, Anthony R. Fooks, Hildegund C. Ertl, Alexander D. Douglas

PLOS Neglected Tropical Diseases: published October 29, 2018 | https://doi.org/10.1371/journal.pntd.0006870

Seroprevalence for the tick-borne relapsing fever spirochete Borrelia turicatae among small and medium sized mammals of Texas

Brittany A. Armstrong, Alexander Kneubehl, Aparna Krishnavajhala, Hannah K. Wilder, William Boyle, Edward Wozniak, Carson Phillips, Kristen Hollywood, Kristy O. Murray, Taylor G. Donaldson, Pete D. Teel, Ken Waldrup, Job E. Lopez

PLOS Neglected Tropical Diseases: published October 29, 2018 | https://doi.org/10.1371/journal.pntd.0006877

Development of reverse genetics systems and investigation of host response antagonism and reassortment potential for Cache Valley and Kairi viruses, two emerging orthobunyaviruses of the Americas

James I. Dunlop, Agnieszka M. Szemiel, Aitor Navarro, Gavin S. Wilkie, Lily Tong, Sejal Modha, Daniel Mair, Vattipally B. Sreenu, Ana Da Silva Filipe, Ping Li, Yan-Jang S. Huang, Benjamin Brennan, Joseph Hughes, Dana L. Vanlandingham, Stephen Higgs, Richard M. Elliott, Alain Kohl

PLOS Neglected Tropical Diseases: published October 29, 2018 | https://doi.org/10.1371/journal.pntd.0006884

Clinical and microscopic predictors of Entamoeba histolytica intestinal infection in travelers and migrants diagnosed with Entamoeba histolytica/dispar infection

Steven Van Den Broucke, Jacob Verschueren, Marjan Van Esbroeck, Emmanuel Bottieau, Jef Van den Ende

PLOS Neglected Tropical Diseases: published October 29, 2018 | https://doi.org/10.1371/journal.pntd.0006892

SODB1 is essential for Leishmania major infection of macrophages and pathogenesis in mice

Bennett J. Davenport, Casey G. Martin, Stephen M. Beverley, David J. Orlicky, Andres Vazquez-Torres, Thomas E. Morrison

PLOS Neglected Tropical Diseases: published October 29, 2018 | https://doi.org/10.1371/journal.pntd.0006921

Participatory survey of Rift Valley fever in nomadic pastoral communities of North-central Nigeria: The associated risk pathways and factors

Nma Bida Alhaji, Olutayo Olajide Babalobi, Yiltawe Wungak, Hussaini Gulak Ularamu

PLOS Neglected Tropical Diseases: published October 30, 2018 | https://doi.org/10.1371/journal.pntd.0006858

An open label randomized clinical trial comparing the safety and effectiveness of one, two or three weekly pentamidine isethionate doses (seven milligrams per kilogram) in the treatment of cutaneous leishmaniasis in the Amazon Region

Ellen Priscilla Nunes Gadelha, Rajendranath Ramasawmy, Bruna da Costa Oliveira, Nágila Morais Rocha, Jorge Augusto de Oliveira Guerra, George Allan Villa Rouco da Silva, Tirza Gabrielle Ramos de Mesquita, Carolina Chrusciak Talhari Cortez, Anette Chrusciak Talhari

PLOS Neglected Tropical Diseases: published October 31, 2018 | https://doi.org/10.1371/journal.pntd.0006850

Epidemiological characterization of incident cases of Rickettsia infection in rural areas of Urabá region, Colombia

Juan Carlos Quintero Vélez, Daniel Camilo Aguirre-Acevedo, Juan David Rodas, Margarita Arboleda, Adriana Troyo, Francisco Vega Aguilar, Lisardo Osorio Quintero, Carlos Rojas Arbeláez

PLOS Neglected Tropical Diseases: published October 31, 2018 | https://doi.org/10.1371/journal.pntd.0006911

Activity profiling of peptidases in Angiostrongylus costaricensis first-stage larvae and adult worms

Karina M. Rebello, James H. McKerrow, Ester M. Mota, Anthony J. O´Donoghue, Ana Gisele C. Neves-Ferreira

PLOS Neglected Tropical Diseases: published October 31, 2018 | https://doi.org/10.1371/journal.pntd.0006923

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