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October 2017

This image shows horses in formation after blood collection in a ranch of the Brazilian Pantanal, during an arbovirus serosurvey in one of the largest freshwater wetlands in the world and an important natural reservoir for sylvatic arboviruses in Brazil. Pauvolid-Corrêa et al.

Image Credit: Alex Pauvolid-Corrêa

Viewpoints

Hepatitis B virus infection as a neglected tropical disease

Geraldine A. O’Hara, Anna L. McNaughton, Tongai Maponga, Pieter Jooste, Ponsiano Ocama, Roma Chilengi, Jolynne Mokaya, Mitchell I. Liyayi, Tabitha Wachira, David M. Gikungi, Lela Burbridge, Denise O’Donnell, Connie S. Akiror, Derek Sloan, Judith Torimiro, Louis Marie Yindom, Robert Walton, Monique Andersson, Kevin Marsh, Robert Newton, Philippa C. Matthews

From Innovation to Application

DenvInt: A database of protein–protein interactions between dengue virus and its hosts

Lopamudra Dey, Anirban Mukhopadhyay

Review

Towards elimination of visceral leishmaniasis in the Indian subcontinent—Translating research to practice to public health

Siddhivinayak Hirve, Axel Kroeger, Greg Matlashewski, Dinesh Mondal, Megha Raj Banjara, Pradeep Das, Ahmed Be-Nazir, Byron Arana, Piero Olliaro

Research Articles

Systematic review of studies generating individual participant data on the efficacy of drugs for treating soil-transmitted helminthiases and the case for data-sharing

Julia B. Halder, Joanne Benton, Amélie M. Julé, Phillipe J. Guérin, Piero L. Olliaro, María-Gloria Basáñez, Martin Walker

Exploratory metabolomics study of the experimental opisthorchiasis in a laboratory animal model (golden hamster, Mesocricetus auratus)

Daria A. Kokova, Sarantos Kostidis, Judit Morello, Nataly Dementeva, Ekaterina A. Perina, Vladimir V. Ivanov, Ludmila M. Ogorodova, Aleksey E. Sazonov, Irina V. Saltykova, Oleg A. Mayboroda

Reassessment of areas with persistent Lymphatic Filariasis nine years after cessation of mass drug administration in Sri Lanka

Ramakrishna U. Rao, Sandhya D. Samarasekera, Kumara C. Nagodavithana, Tharanga D. M. Dassanayaka, Manjula W. Punchihewa, Udaya S. B. Ranasinghe, Gary J. Weil

Wolbachia effects on Rift Valley fever virus infection in Culex tarsalis mosquitoes

Brittany L. Dodson, Elizabeth S. Andrews, Michael J. Turell, Jason L. Rasgon

Ecological niche modeling and distribution of Ornithodoros hermsi associated with tick-borne relapsing fever in western North America

Kylie M. Sage, Tammi L. Johnson, Michael B. Teglas, Nathan C. Nieto, Tom G. Schwan

Molecular characterization and phylogenetic relatedness of dog-derived Rabies Viruses circulating in Cameroon between 2010 and 2016

Serge Alain Sadeuh-Mba, Jean Blaise Momo, Laura Besong, Sévérin Loul, Richard Njouom

A multi-country study of the economic burden of dengue fever: Vietnam, Thailand, and Colombia

Jung-Seok Lee, Vittal Mogasale, Jacqueline K. Lim, Mabel Carabali, Kang-Sung Lee, Chukiat Sirivichayakul, Duc Anh Dang, Diana Cristina Palencia-Florez, Thi Hien Anh Nguyen, Arthorn Riewpaiboon, Pornthep Chanthavanich, Luis Villar, Brian A. Maskery, Andrew Farlow

Complex antigen presentation pathway for an HLA-A*0201-restricted epitope from Chikungunya 6K protein

Elena Lorente, Alejandro Barriga, Juan García-Arriaza, François A. Lemonnier, Mariano Esteban, Daniel López

How familiar are our doctors towards Rabies prophylaxis- A study from coastal south India

Ramesh Holla, Bhagawan Darshan, Astha Guliani, Bhaskaran Unnikrishnan, Rekha Thapar, Prasanna Mithra, Nithin Kumar, Vaman Kulkarni, Avinash Kumar, Salman Anwar

A lethal disease model for New World hantaviruses using immunosuppressed Syrian hamsters

Valentijn Vergote, Lies Laenen, Bert Vanmechelen, Marc Van Ranst, Erik Verbeken, Jay W. Hooper, Piet Maes

RNA-seq transcriptional profiling of Leishmania amazonensis reveals an arginase-dependent gene expression regulation

Juliana Ide Aoki, Sandra Marcia Muxel, Ricardo Andrade Zampieri, Maria Fernanda Laranjeira-Silva, Karl Erik Müller, Audun Helge Nerland, Lucile Maria Floeter-Winter

A polymorphism in the haptoglobin, haptoglobin related protein locus is associated with risk of human sleeping sickness within Cameroonian populations

Elvis Ofon, Harry Noyes, Julius Mulindwa, Hamidou Ilboudo, Martin Simuunza, Vincent Ebo’o, Flobert Njiokou, Mathurin Koffi, Bruno Bucheton, Pythagore Fogue, Christiane Hertz-Fowler, Annette MacLeod, Gustave Simo, for the TrypanoGEN Research Group, as members of The H3Africa Consortium

L-arginine availability and arginase activity: Characterization of amino acid permease 3 in Leishmania amazonensis

Juliana Ide Aoki, Sandra Marcia Muxel, Ricardo Andrade Zampieri, Stephanie Maia Acuña, Juliane Cristina Ribeiro Fernandes, Rubia Heloisa Vanderlinde, Maria Carmen Oliveira de Pinho Sales, Lucile Maria Floeter-Winter

Composition of the Schistosoma mansoni worm secretome: Identification of immune modulatory Cyclophilin A

Achilleas Floudas, Christopher D. Cluxton, Julia Fahel, Adnan R. Khan, Sean P. Saunders, Sylvie Amu, Antonio Alcami, Padraic G. Fallon

The socio-economic burden of human African trypanosomiasis and the coping strategies of households in the South Western Kenya foci

Salome A. Bukachi, Simiyu Wandibba, Isaac K. Nyamongo

Integration of enteric fever surveillance into the WHO-coordinated Invasive Bacterial-Vaccine Preventable Diseases (IB-VPD) platform: A low cost approach to track an increasingly important disease

Senjuti Saha, Maksuda Islam, Mohammad J. Uddin, Shampa Saha, Rajib C. Das, Abdullah H. Baqui, Mathuram Santosham, Robert E. Black, Stephen P. Luby, Samir K. Saha

The cost and cost-effectiveness of rapid testing strategies for yaws diagnosis and surveillance

Christopher Fitzpatrick, Kingsley Asiedu, Anita Sands, Tita Gonzalez Pena, Michael Marks, Oriol Mitja, Filip Meheus, Patrick Van der Stuyft

An α-Gal-containing neoglycoprotein-based vaccine partially protects against murine cutaneous leishmaniasis caused by Leishmania major

Eva Iniguez, Nathaniel S. Schocker, Krishanthi Subramaniam, Susana Portillo, Alba L. Montoya, Waleed S. Al-Salem, Caresse L. Torres, Felipe Rodriguez, Otacilio C. Moreira, Alvaro Acosta-Serrano, Katja Michael, Igor C. Almeida, Rosa A. Maldonado

Giardiasis as a neglected disease in Brazil: Systematic review of 20 years of publications

Camila Henriques Coelho, Maurício Durigan, Diego Averaldo Guiguet Leal, Adriano de Bernardi Schneider, Regina Maura Bueno Franco, Steven M. Singer

Wide Distribution and Genetic Diversity of Babesia microti in Small Mammals from Yunnan Province, Southwestern China

Zi-Hou Gao, Tao-Hua Huang, Bao-Gui Jiang, Na Jia, Zheng-Xiang Liu, Zong-Ti Shao, Rui-Ruo Jiang, Hong-Bo Liu, Ran Wei, Yu-Qiong Li, Hong-Wu Yao, Michael E. von Fricken, Jia-Fu Jiang, Chun-Hong Du, Wu-Chun Cao

Cluster randomized trial comparing school-based mass drug administration schedules in areas of western Kenya with moderate initial prevalence of Schistosoma mansoni infections

Diana M. S. Karanja, Emmy K. Awino, Ryan E. Wiegand, Edward Okoth, Bernard O. Abudho, Pauline N. M. Mwinzi, Susan P. Montgomery, W. Evan Secor

Candidate genes-based investigation of susceptibility to Human African Trypanosomiasis in Côte d’Ivoire

Bernardin Ahouty, Mathurin Koffi, Hamidou Ilboudo, Gustave Simo, Enock Matovu, Julius Mulindwa, Christiane Hertz-Fowler, Bruno Bucheton, Issa Sidibé, Vincent Jamonneau, Annette MacLeod, Harry Noyes, Simon-Pierre N’Guetta, for the TrypanoGEN Research Group as members of The H3Africa Consortium

Cost-effectiveness of adding indoor residual spraying to case management in Afghan refugee settlements in Northwest Pakistan during a prolonged malaria epidemic

Natasha Howard, Lorna Guinness, Mark Rowland, Naeem Durrani, Kristian S. Hansen

Strongyloides stercoralis is associated with significant morbidity in rural Cambodia, including stunting in children

Armelle Forrer, Virak Khieu, Fabian Schär, Jan Hattendorf, Hanspeter Marti, Andreas Neumayr, Meng Chuor Char, Christoph Hatz, Sinuon Muth, Peter Odermatt

Lymphatic pathology in asymptomatic and symptomatic children with Wuchereria bancrofti infection in children from Odisha, India and its reversal with DEC and albendazole treatment

Shantanu K. Kar, Bhagirathi Dwibedi, Birendra K. Das, Bikash K. Agrawala, Cherubala P. Ramachandran, John Horton

The cost of mapping trachoma: Data from the Global Trachoma Mapping Project

Guillaume Trotignon, Ellen Jones, Thomas Engels, Elena Schmidt, Deborah A. McFarland, Colin K. Macleod, Khaled Amer, Amadou A. Bio, Ana Bakhtiari, Sarah Bovill, Amy H. Doherty, Asad Aslam Khan, Mariamo Mbofana, Siobhain McCullagh, Tom Millar, Consity Mwale, Lisa A. Rotondo, Angela Weaver, Rebecca Willis, Anthony W. Solomon

Genome-wide SNPs reveal the drivers of gene flow in an urban population of the Asian Tiger Mosquito, Aedes albopictus

Thomas L. Schmidt, Gordana Rašić, Dongjing Zhang, Xiaoying Zheng, Zhiyong Xi, Ary A. Hoffmann

The study of trypanosome species circulating in domestic animals in two human African trypanosomiasis foci of Côte d'Ivoire identifies pigs and cattle as potential reservoirs of Trypanosoma brucei gambiense

Martial Kassi N’Djetchi, Hamidou Ilboudo, Mathurin Koffi, Jacques Kaboré, Justin Windingoudi Kaboré, Dramane Kaba, Fabrice Courtin, Bamoro Coulibaly, Pierre Fauret, Lingué Kouakou, Sophie Ravel, Stijn Deborggraeve, Philippe Solano, Thierry De Meeûs, Bruno Bucheton, Vincent Jamonneau

Transcriptomic responses of Biomphalaria pfeifferi to Schistosoma mansoni: Investigation of a neglected African snail that supports more S. mansoni transmission than any other snail species

Sarah K. Buddenborg, Lijing Bu, Si-Ming Zhang, Faye D. Schilkey, Gerald M. Mkoji, Eric S. Loker

MicroRNA profiling of human primary macrophages exposed to dengue virus identifies miRNA-3614-5p as antiviral and regulator of ADAR1 expression

Mayra Diosa-Toro, Liliana Echavarría-Consuegra, Jacky Flipse, Geysson Javier Fernández, Joost Kluiver, Anke van den Berg, Silvio Urcuqui-Inchima, Jolanda M. Smit

Preclinical antivenom-efficacy testing reveals potentially disturbing deficiencies of snakebite treatment capability in East Africa

Robert A. Harrison, George O. Oluoch, Stuart Ainsworth, Jaffer Alsolaiss, Fiona Bolton, Ana-Silvia Arias, José-María Gutiérrez, Paul Rowley, Stephen Kalya, Hastings Ozwara, Nicholas R. Casewell

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