Human macrophages derived from THP1 monocytes are infected by Leishmania donovani parasites. The parasites are genetically engineered to express green fluorescent protein (in green). Nuclei of the host cells are stained with DAPI (in red). Images are obtained by confocal fluorescence microscopy at dual excitation/emission channels and superimposed. Automated image analysis renders parasite and macrophage cells counts, as well as number of infected cells, in the absence and presence of drug treatment. Tegazzini D et al.
Image Credit: Imanol Peña-Urquiza
Editorial
Venezuela and its rising vector-borne neglected diseases
PLOS Neglected Tropical Diseases: published June 29, 2017 | https://doi.org/10.1371/journal.pntd.0005423
Viewpoints
Cryptococcal meningitis: A neglected NTD?
PLOS Neglected Tropical Diseases: published June 29, 2017 | https://doi.org/10.1371/journal.pntd.0005575
Challenges in preparing and implementing a clinical trial at field level in an Ebola emergency: A case study in Guinea, West Africa
PLOS Neglected Tropical Diseases: published June 22, 2017 | https://doi.org/10.1371/journal.pntd.0005545
Lessons learned on Zika virus vectors
PLOS Neglected Tropical Diseases: published June 15, 2017 | https://doi.org/10.1371/journal.pntd.0005511
Should the WHO withdraw support for mass deworming?
PLOS Neglected Tropical Diseases: published June 8, 2017 | https://doi.org/10.1371/journal.pntd.0005481
Photo Quiz
A misdiagnosed infection mimicking “tree man disease”
PLOS Neglected Tropical Diseases: published June 15, 2017 | https://doi.org/10.1371/journal.pntd.0005543
Symposiums
Fungemia associated with Schizophyllum commune in Brazil
PLOS Neglected Tropical Diseases: published June 29, 2017 | https://doi.org/10.1371/journal.pntd.0005549
Giant elephantiasis and inguino-scrotal hernia
PLOS Neglected Tropical Diseases: published June 15, 2017 | https://doi.org/10.1371/journal.pntd.0005494
Introducing the TrypanoGEN biobank: A valuable resource for the elimination of human African trypanosomiasis
PLOS Neglected Tropical Diseases: published June 1, 2017 | https://doi.org/10.1371/journal.pntd.0005438
Reviews
Human lagochilascariasis—A rare helminthic disease
PLOS Neglected Tropical Diseases: published June 22, 2017 | https://doi.org/10.1371/journal.pntd.0005510
The enemy within: Targeting host–parasite interaction for antileishmanial drug discovery
PLOS Neglected Tropical Diseases: published June 8, 2017 | https://doi.org/10.1371/journal.pntd.0005480
Research Articles
Intrinsic and extrinsic factors related to pathogen infection in wild small mammals in intensive milk cattle and swine production systems
PLOS Neglected Tropical Diseases: published June 30, 2017 | https://doi.org/10.1371/journal.pntd.0005722
Post-dengue acute disseminated encephalomyelitis: A case report and meta-analysis
PLOS Neglected Tropical Diseases: published June 30, 2017 | https://doi.org/10.1371/journal.pntd.0005715
Essential multimeric enzymes in kinetoplastid parasites: A host of potentially druggable protein-protein interactions
PLOS Neglected Tropical Diseases: published June 29, 2017 | https://doi.org/10.1371/journal.pntd.0005720
Efficacy and safety of available treatments for visceral leishmaniasis in Brazil: A multicenter, randomized, open label trial
PLOS Neglected Tropical Diseases: published June 29, 2017 | https://doi.org/10.1371/journal.pntd.0005706
High risk for chikungunya virus to initiate an enzootic sylvatic cycle in the tropical Americas
PLOS Neglected Tropical Diseases: published June 29, 2017 | https://doi.org/10.1371/journal.pntd.0005698
First evidence of lymphatic filariasis transmission interruption in Cameroon: Progress towards elimination
PLOS Neglected Tropical Diseases: published June 29, 2017 | https://doi.org/10.1371/journal.pntd.0005633
Genome-scale analysis of the genes that contribute to Burkholderia pseudomallei biofilm formation identifies a crucial exopolysaccharide biosynthesis gene cluster
PLOS Neglected Tropical Diseases: published June 28, 2017 | https://doi.org/10.1371/journal.pntd.0005689
Leptospira diversity in animals and humans in Tahiti, French Polynesia
PLOS Neglected Tropical Diseases: published June 28, 2017 | https://doi.org/10.1371/journal.pntd.0005676
Chronic Trichuris muris infection causes neoplastic change in the intestine and exacerbates tumour formation in APC min/+ mice
PLOS Neglected Tropical Diseases: published June 26, 2017 | https://doi.org/10.1371/journal.pntd.0005708
Urban Chikungunya in the Middle East and North Africa: A systematic review
PLOS Neglected Tropical Diseases: published June 26, 2017 | https://doi.org/10.1371/journal.pntd.0005707
Effect of praziquantel on the differential expression of mouse hepatic genes and parasite ATP binding cassette transporter gene family members during Schistosoma mansoni infection
PLOS Neglected Tropical Diseases: published June 26, 2017 | https://doi.org/10.1371/journal.pntd.0005691
Novel inference models for estimation of abundance, survivorship and recruitment in mosquito populations using mark-release-recapture data
PLOS Neglected Tropical Diseases: published June 26, 2017 | https://doi.org/10.1371/journal.pntd.0005682
A study of ticks and tick-borne livestock pathogens in Pakistan
PLOS Neglected Tropical Diseases: published June 26, 2017 | https://doi.org/10.1371/journal.pntd.0005681
Interleukin-4 receptor alpha is still required after Th2 polarization for the maintenance and the recall of protective immunity to Nematode infection
PLOS Neglected Tropical Diseases: published June 26, 2017 | https://doi.org/10.1371/journal.pntd.0005675
Point-of-care testing for Toxoplasma gondii IgG/IgM using Toxoplasma ICT IgG-IgM test with sera from the United States and implications for developing countries
PLOS Neglected Tropical Diseases: published June 26, 2017 | https://doi.org/10.1371/journal.pntd.0005670
Peridomestic Aedes malayensis and Aedes albopictus are capable vectors of arboviruses in cities
PLOS Neglected Tropical Diseases: published June 26, 2017 | https://doi.org/10.1371/journal.pntd.0005667
Suppression of chikungunya virus replication and differential innate responses of human peripheral blood mononuclear cells during co-infection with dengue virus
PLOS Neglected Tropical Diseases: published June 23, 2017 | https://doi.org/10.1371/journal.pntd.0005712
Evaluation of different serological assays for early diagnosis of leptospirosis in Martinique (French West Indies)
PLOS Neglected Tropical Diseases: published June 23, 2017 | https://doi.org/10.1371/journal.pntd.0005678
The interplay of climate, intervention and imported cases as determinants of the 2014 dengue outbreak in Guangzhou
PLOS Neglected Tropical Diseases: published June 22, 2017 | https://doi.org/10.1371/journal.pntd.0005701
Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children
PLOS Neglected Tropical Diseases: published June 22, 2017 | https://doi.org/10.1371/journal.pntd.0005679
Estimating the number of secondary Ebola cases resulting from an unsafe burial and risk factors for transmission during the West Africa Ebola epidemic
PLOS Neglected Tropical Diseases: published June 22, 2017 | https://doi.org/10.1371/journal.pntd.0005491
The formation of lipid droplets favors intracellular Mycobacterium leprae survival in SW-10, non-myelinating Schwann cells
PLOS Neglected Tropical Diseases: published June 21, 2017 | https://doi.org/10.1371/journal.pntd.0005687
Incidence and mortality due to snakebite in the Americas
PLOS Neglected Tropical Diseases: published June 21, 2017 | https://doi.org/10.1371/journal.pntd.0005662
Esperanza Window Traps for the collection of anthropophilic blackflies (Diptera: Simuliidae) in Uganda and Tanzania
PLOS Neglected Tropical Diseases: published June 19, 2017 | https://doi.org/10.1371/journal.pntd.0005688
Immunosuppressive and angiogenic cytokine profile associated with Bartonella bacilliformis infection in post-outbreak and endemic areas of Carrion's disease in Peru
PLOS Neglected Tropical Diseases: published June 19, 2017 | https://doi.org/10.1371/journal.pntd.0005684
LAMPhimerus: A novel LAMP assay for detecting Amphimerus sp. DNA in human stool samples
PLOS Neglected Tropical Diseases: published June 19, 2017 | https://doi.org/10.1371/journal.pntd.0005672
Comparative analysis of European bat lyssavirus 1 pathogenicity in the mouse model
PLOS Neglected Tropical Diseases: published June 19, 2017 | https://doi.org/10.1371/journal.pntd.0005668
South African Ebola diagnostic response in Sierra Leone: A modular high biosafety field laboratory
PLOS Neglected Tropical Diseases: published June 19, 2017 | https://doi.org/10.1371/journal.pntd.0005665
Host gene expression analysis in Sri Lankan melioidosis patients
PLOS Neglected Tropical Diseases: published June 19, 2017 | https://doi.org/10.1371/journal.pntd.0005643
Therapeutic administration of a recombinant human monoclonal antibody reduces the severity of chikungunya virus disease in rhesus macaques
PLOS Neglected Tropical Diseases: published June 19, 2017 | https://doi.org/10.1371/journal.pntd.0005637
Flavivirus and Filovirus EvoPrinters: New alignment tools for the comparative analysis of viral evolution
PLOS Neglected Tropical Diseases: published June 16, 2017 | https://doi.org/10.1371/journal.pntd.0005673
Minimal genetic change in Vibrio cholerae in Mozambique over time: Multilocus variable number tandem repeat analysis and whole genome sequencing
PLOS Neglected Tropical Diseases: published June 16, 2017 | https://doi.org/10.1371/journal.pntd.0005671
Comparison of monocyte gene expression among patients with neurocysticercosis-associated epilepsy, Idiopathic Epilepsy and idiopathic headaches in India
PLOS Neglected Tropical Diseases: published June 16, 2017 | https://doi.org/10.1371/journal.pntd.0005664
Sterol 14α-demethylase mutation leads to amphotericin B resistance in Leishmania mexicana
PLOS Neglected Tropical Diseases: published June 16, 2017 | https://doi.org/10.1371/journal.pntd.0005649
Dengue seroprevalence and force of primary infection in a representative population of urban dwelling Indonesian children
PLOS Neglected Tropical Diseases: published June 15, 2017 | https://doi.org/10.1371/journal.pntd.0005621
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Co-occurrence of viruses and mosquitoes at the vectors’ optimal climate range: An underestimated risk to temperate regions?
PLOS Neglected Tropical Diseases: published June 15, 2017 | https://doi.org/10.1371/journal.pntd.0005604
Whole genome sequencing distinguishes between relapse and reinfection in recurrent leprosy cases
PLOS Neglected Tropical Diseases: published June 15, 2017 | https://doi.org/10.1371/journal.pntd.0005598
Burden of trachoma in five counties of Eastern Equatoria state, South Sudan: Results from population-based surveys
PLOS Neglected Tropical Diseases: published June 14, 2017 | https://doi.org/10.1371/journal.pntd.0005658
First report of naturally infected Aedes aegypti with chikungunya virus genotype ECSA in the Americas
PLOS Neglected Tropical Diseases: published June 14, 2017 | https://doi.org/10.1371/journal.pntd.0005630
Comparative genomics of Cryptococcus neoformans var. grubii associated with meningitis in HIV infected and uninfected patients in Vietnam
PLOS Neglected Tropical Diseases: published June 14, 2017 | https://doi.org/10.1371/journal.pntd.0005628
The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei
PLOS Neglected Tropical Diseases: published June 13, 2017 | https://doi.org/10.1371/journal.pntd.0005626
Identification of antigenic Sarcoptes scabiei proteins for use in a diagnostic test and of non-antigenic proteins that may be immunomodulatory
PLOS Neglected Tropical Diseases: published June 12, 2017 | https://doi.org/10.1371/journal.pntd.0005669
Challenges in developing methods for quantifying the effects of weather and climate on water-associated diseases: A systematic review
PLOS Neglected Tropical Diseases: published June 12, 2017 | https://doi.org/10.1371/journal.pntd.0005659
Deltamethrin resistance in Aedes aegypti results in treatment failure in Merida, Mexico
PLOS Neglected Tropical Diseases: published June 12, 2017 | https://doi.org/10.1371/journal.pntd.0005656
A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus
PLOS Neglected Tropical Diseases: published June 12, 2017 | https://doi.org/10.1371/journal.pntd.0005655
Burden and impact of Plasmodium vivax in pregnancy: A multi-centre prospective observational study
PLOS Neglected Tropical Diseases: published June 12, 2017 | https://doi.org/10.1371/journal.pntd.0005606
Pediatric melioidosis in Sarawak, Malaysia: Epidemiological, clinical and microbiological characteristics
PLOS Neglected Tropical Diseases: published June 9, 2017 | https://doi.org/10.1371/journal.pntd.0005650
Extraparenchymal neurocysticercosis: Demographic, clinicoradiological, and inflammatory features
PLOS Neglected Tropical Diseases: published June 9, 2017 | https://doi.org/10.1371/journal.pntd.0005646
Expression of inhibitory receptors and polyfunctional responses of T cells are linked to the risk of congenital transmission of T. cruzi
PLOS Neglected Tropical Diseases: published June 9, 2017 | https://doi.org/10.1371/journal.pntd.0005627
Neighborhood-targeted and case-triggered use of a single dose of oral cholera vaccine in an urban setting: Feasibility and vaccine coverage
PLOS Neglected Tropical Diseases: published June 8, 2017 | https://doi.org/10.1371/journal.pntd.0005652
An individual-level meta-analysis assessing the impact of community-level sanitation access on child stunting, anemia, and diarrhea: Evidence from DHS and MICS surveys
PLOS Neglected Tropical Diseases: published June 8, 2017 | https://doi.org/10.1371/journal.pntd.0005591
LAMP-2 absence interferes with plasma membrane repair and decreases T. cruzi host cell invasion
PLOS Neglected Tropical Diseases: published June 6, 2017 | https://doi.org/10.1371/journal.pntd.0005657
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Transmission dynamics and control of Rickettsia rickettsii in populations of Hydrochoerus hydrochaeris and Amblyomma sculptum
PLOS Neglected Tropical Diseases: published June 5, 2017 | https://doi.org/10.1371/journal.pntd.0005613
Accuracy of parasitological and immunological tests for the screening of human schistosomiasis in immigrants and refugees from African countries: An approach with Latent Class Analysis
PLOS Neglected Tropical Diseases: published June 5, 2017 | https://doi.org/10.1371/journal.pntd.0005593
Increased miltefosine tolerance in clinical isolates of Leishmania donovani is associated with reduced drug accumulation, increased infectivity and resistance to oxidative stress
PLOS Neglected Tropical Diseases: published June 2, 2017 | https://doi.org/10.1371/journal.pntd.0005641
Radiological evolution of porcine neurocysticercosis after combined antiparasitic treatment with praziquantel and albendazole
PLOS Neglected Tropical Diseases: published June 2, 2017 | https://doi.org/10.1371/journal.pntd.0005624
Ebola virus disease contact tracing activities, lessons learned and best practices during the Duport Road outbreak in Monrovia, Liberia, November 2015
PLOS Neglected Tropical Diseases: published June 2, 2017 | https://doi.org/10.1371/journal.pntd.0005597
Mosquito co-infection with Zika and chikungunya virus allows simultaneous transmission without affecting vector competence of Aedes aegypti
PLOS Neglected Tropical Diseases: published June 1, 2017 | https://doi.org/10.1371/journal.pntd.0005654
Rabies surveillance in dogs in Lao PDR from 2010-2016
PLOS Neglected Tropical Diseases: published June 1, 2017 | https://doi.org/10.1371/journal.pntd.0005609
Prevalence of depression and associated clinical and socio-demographic factors in people living with lymphatic filariasis in Plateau State, Nigeria
PLOS Neglected Tropical Diseases: published June 1, 2017 | https://doi.org/10.1371/journal.pntd.0005567
qPCR-High resolution melt analysis for drug susceptibility testing of Mycobacterium leprae directly from clinical specimens of leprosy patients
PLOS Neglected Tropical Diseases: published June 1, 2017 | https://doi.org/10.1371/journal.pntd.0005506