Bats are now associated with several deadly emerging viruses, including Hendra, Nipah, Marburg, and Ebola and Severe Acute Respiratory Syndrome coronavirus (SARS CoV). Understanding the biology of these pathogens within and among their hosts is essential for predicting and managing zoonoses. Plowright et al.
Image Credit: Raina Plowright
Editorials
NTD and NCD Co-morbidities: The Example of Dengue Fever
PLOS Neglected Tropical Diseases: published August 25, 2016 | https://doi.org/10.1371/journal.pntd.0004619
Challenges to the Design of Clinical Trials for Live-Attenuated Tetravalent Dengue Vaccines
PLOS Neglected Tropical Diseases: published August 11, 2016 | https://doi.org/10.1371/journal.pntd.0004854
Viewpoints
Dengue in the Context of the Integrated Management of Childhood Illness
PLOS Neglected Tropical Diseases: published August 25, 2016 | https://doi.org/10.1371/journal.pntd.0004838
Next Steps for Ebola Vaccination: Deployment in Non-Epidemic, High-Risk Settings
PLOS Neglected Tropical Diseases: published August 18, 2016 | https://doi.org/10.1371/journal.pntd.0004802
Symposiums
Meeting Report: Translational Considerations of Novel Vector Management Approaches
PLOS Neglected Tropical Diseases: published August 11, 2016 | https://doi.org/10.1371/journal.pntd.0004800
Madurella mycetomatis-Induced Massive Shoulder Joint Destruction: A Management Challenge
PLOS Neglected Tropical Diseases: published August 4, 2016 | https://doi.org/10.1371/journal.pntd.0004849
Reviews
Zika Fetal Neuropathogenesis: Etiology of a Viral Syndrome
PLOS Neglected Tropical Diseases: published August 25, 2016 | https://doi.org/10.1371/journal.pntd.0004877
The Case for Live Attenuated Vaccines against the Neglected Zoonotic Diseases Brucellosis and Bovine Tuberculosis
PLOS Neglected Tropical Diseases: published August 18, 2016 | https://doi.org/10.1371/journal.pntd.0004572
Transmission or Within-Host Dynamics Driving Pulses of Zoonotic Viruses in Reservoir–Host Populations
PLOS Neglected Tropical Diseases: published August 4, 2016 | https://doi.org/10.1371/journal.pntd.0004796
Research Articles
Morinda citrifolia Linn. Reduces Parasite Load and Modulates Cytokines and Extracellular Matrix Proteins in C57BL/6 Mice Infected with Leishmania (Leishmania) amazonensis
PLOS Neglected Tropical Diseases: published August 31, 2016 | https://doi.org/10.1371/journal.pntd.0004900
Live Attenuated Leishmania donovani Centrin Knock Out Parasites Generate Non-inferior Protective Immune Response in Aged Mice against Visceral Leishmaniasis
PLOS Neglected Tropical Diseases: published August 31, 2016 | https://doi.org/10.1371/journal.pntd.0004963
The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor
PLOS Neglected Tropical Diseases: published August 31, 2016 | https://doi.org/10.1371/journal.pntd.0004969
Identification of Tenrec ecaudatus, a Wild Mammal Introduced to Mayotte Island, as a Reservoir of the Newly Identified Human Pathogenic Leptospira mayottensis
PLOS Neglected Tropical Diseases: published August 30, 2016 | https://doi.org/10.1371/journal.pntd.0004933
Over Six Thousand Trypanosoma cruzi Strains Classified into Discrete Typing Units (DTUs): Attempt at an Inventory
PLOS Neglected Tropical Diseases: published August 29, 2016 | https://doi.org/10.1371/journal.pntd.0004792
Development of 2, 7-Diamino-1, 8-Naphthyridine (DANP) Anchored Hairpin Primers for RT-PCR Detection of Chikungunya Virus Infection
PLOS Neglected Tropical Diseases: published August 29, 2016 | https://doi.org/10.1371/journal.pntd.0004887
Antigenic Variation of East/Central/South African and Asian Chikungunya Virus Genotypes in Neutralization by Immune Sera
PLOS Neglected Tropical Diseases: published August 29, 2016 | https://doi.org/10.1371/journal.pntd.0004960
Serum Procalcitonin and Peripheral Venous Lactate for Predicting Dengue Shock and/or Organ Failure: A Prospective Observational Study
PLOS Neglected Tropical Diseases: published August 26, 2016 | https://doi.org/10.1371/journal.pntd.0004961
Clonal Evolution of Enterocytozoon bieneusi Populations in Swine and Genetic Differentiation in Subpopulations between Isolates from Swine and Humans
PLOS Neglected Tropical Diseases: published August 26, 2016 | https://doi.org/10.1371/journal.pntd.0004966
An Ecological Assessment of the Pandemic Threat of Zika Virus
PLOS Neglected Tropical Diseases: published August 26, 2016 | https://doi.org/10.1371/journal.pntd.0004968
Mp1p Is a Virulence Factor in Talaromyces (Penicillium) marneffei
PLOS Neglected Tropical Diseases: published August 25, 2016 | https://doi.org/10.1371/journal.pntd.0004907
Sero-Molecular Epidemiology of Japanese Encephalitis in Zhejiang, an Eastern Province of China
PLOS Neglected Tropical Diseases: published August 25, 2016 | https://doi.org/10.1371/journal.pntd.0004936
Identification of RNA Binding Proteins Associated with Dengue Virus RNA in Infected Cells Reveals Temporally Distinct Host Factor Requirements
PLOS Neglected Tropical Diseases: published August 24, 2016 | https://doi.org/10.1371/journal.pntd.0004921
Incidence and Risk Factors for Developing Dengue-Associated Hemophagocytic Lymphohistiocytosis in Puerto Rico, 2008 - 2013
PLOS Neglected Tropical Diseases: published August 24, 2016 | https://doi.org/10.1371/journal.pntd.0004939
Expression of CD64 on Circulating Neutrophils Favoring Systemic Inflammatory Status in Erythema Nodosum Leprosum
PLOS Neglected Tropical Diseases: published August 24, 2016 | https://doi.org/10.1371/journal.pntd.0004955
Mortality, Morbidity and Health-Seeking Behaviour during the Ebola Epidemic 2014–2015 in Monrovia Results from a Mobile Phone Survey
PLOS Neglected Tropical Diseases: published August 23, 2016 | https://doi.org/10.1371/journal.pntd.0004899
Prevalence of Active and Latent Yaws in the Solomon Islands 18 Months after Azithromycin Mass Drug Administration for Trachoma
PLOS Neglected Tropical Diseases: published August 23, 2016 | https://doi.org/10.1371/journal.pntd.0004927
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Differential Gel Electrophoresis (DIGE) Evaluation of Naphthoimidazoles Mode of Action: A Study in Trypanosoma cruzi Bloodstream Trypomastigotes
PLOS Neglected Tropical Diseases: published August 23, 2016 | https://doi.org/10.1371/journal.pntd.0004951
Ivermectin Treatment and Sanitation Effectively Reduce Strongyloides stercoralis Infection Risk in Rural Communities in Cambodia
PLOS Neglected Tropical Diseases: published August 22, 2016 | https://doi.org/10.1371/journal.pntd.0004909
Evaluating the Burden of Lymphedema Due to Lymphatic Filariasis in 2005 in Khurda District, Odisha State, India
PLOS Neglected Tropical Diseases: published August 22, 2016 | https://doi.org/10.1371/journal.pntd.0004917
Community Involvement in Dengue Outbreak Control: An Integrated Rigorous Intervention Strategy
PLOS Neglected Tropical Diseases: published August 22, 2016 | https://doi.org/10.1371/journal.pntd.0004919
Liver Necrosis and Lethal Systemic Inflammation in a Murine Model of Rickettsia typhi Infection: Role of Neutrophils, Macrophages and NK Cells
PLOS Neglected Tropical Diseases: published August 22, 2016 | https://doi.org/10.1371/journal.pntd.0004935
Knowledge, Attitudes, and Practices regarding Diarrhea and Cholera following an Oral Cholera Vaccination Campaign in the Solomon Islands
PLOS Neglected Tropical Diseases: published August 22, 2016 | https://doi.org/10.1371/journal.pntd.0004937
West Nile Virus Temperature Sensitivity and Avian Virulence Are Modulated by NS1-2B Polymorphisms
PLOS Neglected Tropical Diseases: published August 22, 2016 | https://doi.org/10.1371/journal.pntd.0004938
Cystic Echinococcosis Epidemiology in Spain Based on Hospitalization Records, 1997-2012
PLOS Neglected Tropical Diseases: published August 22, 2016 | https://doi.org/10.1371/journal.pntd.0004942
The Impact of Short-Term, Intensive Antifolate Treatment (with Pyrimethamine and Sulfadoxine) and Antibiotics Followed by Long-Term, Secondary Antifolate Prophylaxis on the Rate of Toxoplasmic Retinochoroiditis Recurrence
PLOS Neglected Tropical Diseases: published August 19, 2016 | https://doi.org/10.1371/journal.pntd.0004892
Dengue Sentinel Traveler Surveillance: Monthly and Yearly Notification Trends among Japanese Travelers, 2006–2014
PLOS Neglected Tropical Diseases: published August 19, 2016 | https://doi.org/10.1371/journal.pntd.0004924
Working with Zika and Usutu Viruses In Vitro
PLOS Neglected Tropical Diseases: published August 19, 2016 | https://doi.org/10.1371/journal.pntd.0004931
Visceral Leishmaniasis on the Indian Subcontinent: Modelling the Dynamic Relationship between Vector Control Schemes and Vector Life Cycles
PLOS Neglected Tropical Diseases: published August 18, 2016 | https://doi.org/10.1371/journal.pntd.0004868
Using Qualitative Methods to Explore Lay Explanatory Models, Health-Seeking Behaviours and Self-Care Practices of Podoconiosis Patients in North-West Ethiopia
PLOS Neglected Tropical Diseases: published August 18, 2016 | https://doi.org/10.1371/journal.pntd.0004878
Symptomatic Dengue Disease in Five Southeast Asian Countries: Epidemiological Evidence from a Dengue Vaccine Trial
PLOS Neglected Tropical Diseases: published August 17, 2016 | https://doi.org/10.1371/journal.pntd.0004918
Proposing a Compartmental Model for Leprosy and Parameterizing Using Regional Incidence in Brazil
PLOS Neglected Tropical Diseases: published August 17, 2016 | https://doi.org/10.1371/journal.pntd.0004925
Using a Human Challenge Model of Infection to Measure Vaccine Efficacy: A Randomised, Controlled Trial Comparing the Typhoid Vaccines M01ZH09 with Placebo and Ty21a
PLOS Neglected Tropical Diseases: published August 17, 2016 | https://doi.org/10.1371/journal.pntd.0004926
Efficacy, Safety and Cost of Insecticide Treated Wall Lining, Insecticide Treated Bed Nets and Indoor Wall Wash with Lime for Visceral Leishmaniasis Vector Control in the Indian Sub-continent: A Multi-country Cluster Randomized Controlled Trial
PLOS Neglected Tropical Diseases: published August 17, 2016 | https://doi.org/10.1371/journal.pntd.0004932
Population Genetic Analysis Reveals a High Genetic Diversity in the Brazilian Cryptococcus gattii VGII Population and Shifts the Global Origin from the Amazon Rainforest to the Semi-arid Desert in the Northeast of Brazil
PLOS Neglected Tropical Diseases: published August 16, 2016 | https://doi.org/10.1371/journal.pntd.0004885
Distribution and Diversity of Pathogenic Leptospira Species in Peri-domestic Surface Waters from South Central Chile
PLOS Neglected Tropical Diseases: published August 16, 2016 | https://doi.org/10.1371/journal.pntd.0004895
Factors Associated with Ivermectin Non-Compliance and Its Potential Role in Sustaining Onchocerca volvulus Transmission in the West Region of Cameroon
PLOS Neglected Tropical Diseases: published August 16, 2016 | https://doi.org/10.1371/journal.pntd.0004905
Leukocyte Lysis and Cytokine Induction by the Human Sexually Transmitted Parasite Trichomonas vaginalis
PLOS Neglected Tropical Diseases: published August 16, 2016 | https://doi.org/10.1371/journal.pntd.0004913
The Effects of Ivermectin on Brugia malayi Females In Vitro: A Transcriptomic Approach
PLOS Neglected Tropical Diseases: published August 16, 2016 | https://doi.org/10.1371/journal.pntd.0004929
Reduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F1Fo-ATPase
PLOS Neglected Tropical Diseases: published August 12, 2016 | https://doi.org/10.1371/journal.pntd.0004791
Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems
PLOS Neglected Tropical Diseases: published August 12, 2016 | https://doi.org/10.1371/journal.pntd.0004928
Invasive Non-typhoidal Salmonella Infections in Asia: Clinical Observations, Disease Outcome and Dominant Serovars from an Infectious Disease Hospital in Vietnam
PLOS Neglected Tropical Diseases: published August 11, 2016 | https://doi.org/10.1371/journal.pntd.0004857
A Cost-Effectiveness Tool to Guide the Prioritization of Interventions for Rheumatic Fever and Rheumatic Heart Disease Control in African Nations
PLOS Neglected Tropical Diseases: published August 11, 2016 | https://doi.org/10.1371/journal.pntd.0004860
Lipophosphoglycans from Leishmania amazonensis Strains Display Immunomodulatory Properties via TLR4 and Do Not Affect Sand Fly Infection
PLOS Neglected Tropical Diseases: published August 10, 2016 | https://doi.org/10.1371/journal.pntd.0004848
Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients
PLOS Neglected Tropical Diseases: published August 10, 2016 | https://doi.org/10.1371/journal.pntd.0004851
Novel Ordered Stepped-Wedge Cluster Trial Designs for Detecting Ebola Vaccine Efficacy Using a Spatially Structured Mathematical Model
PLOS Neglected Tropical Diseases: published August 10, 2016 | https://doi.org/10.1371/journal.pntd.0004866
Economic Analysis of the Impact of Overseas and Domestic Treatment and Screening Options for Intestinal Helminth Infection among US-Bound Refugees from Asia
PLOS Neglected Tropical Diseases: published August 10, 2016 | https://doi.org/10.1371/journal.pntd.0004910
Rheopathologic Consequence of Plasmodium vivax Rosette Formation
PLOS Neglected Tropical Diseases: published August 10, 2016 | https://doi.org/10.1371/journal.pntd.0004912
Evaluation of a Urine Pooling Strategy for the Rapid and Cost-Efficient Prevalence Classification of Schistosomiasis
PLOS Neglected Tropical Diseases: published August 9, 2016 | https://doi.org/10.1371/journal.pntd.0004894
Zika Virus, a New Threat for Europe?
PLOS Neglected Tropical Diseases: published August 9, 2016 | https://doi.org/10.1371/journal.pntd.0004901
Alternatively Activated Mononuclear Phagocytes from the Skin Site of Infection and the Impact of IL-4Rα Signalling on CD4+T Cell Survival in Draining Lymph Nodes after Repeated Exposure to Schistosoma mansoni Cercariae
PLOS Neglected Tropical Diseases: published August 9, 2016 | https://doi.org/10.1371/journal.pntd.0004911
Human Rabies in China, 1960-2014: A Descriptive Epidemiological Study
PLOS Neglected Tropical Diseases: published August 8, 2016 | https://doi.org/10.1371/journal.pntd.0004874
Cysteine and Aspartyl Proteases Contribute to Protein Digestion in the Gut of Freshwater Planaria
PLOS Neglected Tropical Diseases: published August 8, 2016 | https://doi.org/10.1371/journal.pntd.0004893
Calculation of the Average Cost per Case of Dengue Fever in Mexico Using a Micro-Costing Approach
PLOS Neglected Tropical Diseases: published August 8, 2016 | https://doi.org/10.1371/journal.pntd.0004897
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MLST and Whole-Genome-Based Population Analysis of Cryptococcus gattii VGIII Links Clinical, Veterinary and Environmental Strains, and Reveals Divergent Serotype Specific Sub-populations and Distant Ancestors
PLOS Neglected Tropical Diseases: published August 5, 2016 | https://doi.org/10.1371/journal.pntd.0004861
A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense
PLOS Neglected Tropical Diseases: published August 5, 2016 | https://doi.org/10.1371/journal.pntd.0004903
Leishmania donovani Utilize Sialic Acids for Binding and Phagocytosis in the Macrophages through Selective Utilization of Siglecs and Impair the Innate Immune Arm
PLOS Neglected Tropical Diseases: published August 5, 2016 | https://doi.org/10.1371/journal.pntd.0004904
Estimating Geographical Variation in the Risk of Zoonotic Plasmodium knowlesi Infection in Countries Eliminating Malaria
PLOS Neglected Tropical Diseases: published August 5, 2016 | https://doi.org/10.1371/journal.pntd.0004915
A Proteomic Investigation of Hepatic Resistance to Ascaris in a Murine Model
PLOS Neglected Tropical Diseases: published August 4, 2016 | https://doi.org/10.1371/journal.pntd.0004837
Transmission Dynamics of Visceral Leishmaniasis in the Indian Subcontinent – A Systematic Literature Review
PLOS Neglected Tropical Diseases: published August 4, 2016 | https://doi.org/10.1371/journal.pntd.0004896
Compounds Derived from the Bhutanese Daisy, Ajania nubigena, Demonstrate Dual Anthelmintic Activity against Schistosoma mansoni and Trichuris muris
PLOS Neglected Tropical Diseases: published August 4, 2016 | https://doi.org/10.1371/journal.pntd.0004908
Leptospira Seroprevalence and Risk Factors in Health Centre Patients in Hoima District, Western Uganda
PLOS Neglected Tropical Diseases: published August 3, 2016 | https://doi.org/10.1371/journal.pntd.0004858
Tourniquet Test for Dengue Diagnosis: Systematic Review and Meta-analysis of Diagnostic Test Accuracy
PLOS Neglected Tropical Diseases: published August 3, 2016 | https://doi.org/10.1371/journal.pntd.0004888
Rabies in Kazakhstan
PLOS Neglected Tropical Diseases: published August 3, 2016 | https://doi.org/10.1371/journal.pntd.0004889
Molecular Identification of Hookworm Isolates in Humans, Dogs and Soil in a Tribal Area in Tamil Nadu, India
PLOS Neglected Tropical Diseases: published August 3, 2016 | https://doi.org/10.1371/journal.pntd.0004891
Blinding Trachoma: Systematic Review of Rates and Risk Factors for Progressive Disease
PLOS Neglected Tropical Diseases: published August 2, 2016 | https://doi.org/10.1371/journal.pntd.0004859
Surface Molecules Released by Trypanosoma cruzi Metacyclic Forms Downregulate Host Cell Invasion
PLOS Neglected Tropical Diseases: published August 2, 2016 | https://doi.org/10.1371/journal.pntd.0004883
Hand Mycetoma: The Mycetoma Research Centre Experience and Literature Review
PLOS Neglected Tropical Diseases: published August 2, 2016 | https://doi.org/10.1371/journal.pntd.0004886
Post-exposure Treatment with Anti-rabies VHH and Vaccine Significantly Improves Protection of Mice from Lethal Rabies Infection
PLOS Neglected Tropical Diseases: published August 2, 2016 | https://doi.org/10.1371/journal.pntd.0004902
Limited Effects of Type I Interferons on Kyasanur Forest Disease Virus in Cell Culture
PLOS Neglected Tropical Diseases: published August 1, 2016 | https://doi.org/10.1371/journal.pntd.0004871
Spatiotemporal Dynamics of Scrub Typhus Transmission in Mainland China, 2006-2014
PLOS Neglected Tropical Diseases: published August 1, 2016 | https://doi.org/10.1371/journal.pntd.0004875
Profiling of Intracellular Metabolites: An Approach to Understanding the Characteristic Physiology of Mycobacterium leprae
PLOS Neglected Tropical Diseases: published August 1, 2016 | https://doi.org/10.1371/journal.pntd.0004881
An Intradermal Inoculation Mouse Model for Immunological Investigations of Acute Scrub Typhus and Persistent Infection
PLOS Neglected Tropical Diseases: published August 1, 2016 | https://doi.org/10.1371/journal.pntd.0004884