May 2015

This study illustrates that secondary triatomine vector species, such as Pantrongylus liganrius, seen in this image, are responsible for a significant burden of Chagas disease. This species, P. lignarius, is known to inhabit both domestic and sylvatic ecotopes, and was the only vector species collected in this study. Levy et al.

Image Credit: C. Bern

Editorials

Hepatitis B Vaccines and HPV Vaccines Have Been Hailed as Major Public Health Achievements in Preventing Cancer—Could a Schistosomiasis Vaccine be the Third?

Michael H. Hsieh, Julia M. L. Brotherton, Afzal A. Siddiqui

PLOS Neglected Tropical Diseases: published May 28, 2015 | https://doi.org/10.1371/journal.pntd.0003598

40 Years of the APOC Partnership

Jean-Baptist Roungou, Laurent Yameogo, Chris Mwikisa, Daniel A. Boakye, Donald A. P. Bundy

PLOS Neglected Tropical Diseases: published May 14, 2015 | https://doi.org/10.1371/journal.pntd.0003562

Policy Platform

Snakebites and Scorpion Stings in the Brazilian Amazon: Identifying Research Priorities for a Largely Neglected Problem

Fan Hui Wen, Wuelton Marcelo Monteiro, Ana Maria Moura da Silva, Denise V. Tambourgi, Iran Mendonça da Silva, Vanderson S. Sampaio, Maria Cristina dos Santos, Jacqueline Sachett, Luiz Carlos L. Ferreira, Jorge Kalil, Marcus Lacerda

PLOS Neglected Tropical Diseases: published May 21, 2015 | https://doi.org/10.1371/journal.pntd.0003701

Enabling the Development and Deployment of Next Generation Point-of-Care Diagnostics

Ratmir Derda, Jesse Gitaka, Catherine M. Klapperich, Charles R. Mace, Ashok A. Kumar, Marya Lieberman, Jacqueline C. Linnes, Joerg Jores, Johnson Nasimolo, Joseph Ndung’u, Evans Taracha, Abigail Weaver, Douglas B. Weibel, Thomas M. Kariuki, Paul Yager

PLOS Neglected Tropical Diseases: published May 14, 2015 | https://doi.org/10.1371/journal.pntd.0003676

Historical Profiles and Perspectives

From River Blindness to Neglected Tropical Diseases—Lessons Learned in Africa for Programme Implementation and Expansion by the Non-governmental Partners

Catherine Cross, Franca Olamiju, Frank Richards, Simon Bush, Adrian Hopkins, Danny Haddad

PLOS Neglected Tropical Diseases: published May 14, 2015 | https://doi.org/10.1371/journal.pntd.0003506

Growth, Challenges, and Solutions over 25 Years of Mectizan and the Impact on Onchocerciasis Control

Joni Lawrence, Yao K. Sodahlon, Kisito T. Ogoussan, Adrian D. Hopkins

PLOS Neglected Tropical Diseases: published May 14, 2015 | https://doi.org/10.1371/journal.pntd.0003507

Investing in Onchocerciasis Control: Financial Management of the African Programme for Onchocerciasis Control (APOC)

Donald A. P. Bundy, Bilkiss Dhomun, Xavier Daney, Linda B. Schultz, Andy Tembon

PLOS Neglected Tropical Diseases: published May 14, 2015 | https://doi.org/10.1371/journal.pntd.0003508

Managing the Fight against Onchocerciasis in Africa: APOC Experience

Grace Fobi, Laurent Yameogo, Mounkaila Noma, Yaovi Aholou, Joseph B. Koroma, Honorat M. Zouré, Tony Ukety, Paul-Samson Lusamba-Dikassa, Chris Mwikisa, Daniel A. Boakye, Jean-Baptist Roungou

PLOS Neglected Tropical Diseases: published May 14, 2015 | https://doi.org/10.1371/journal.pntd.0003542

Symposium

Negativation of Trypanosoma cruzi PCR within Six Months after Treatment of a Child with Nifurtimox

Lauren Pull, Feriel Touafek, Luc Paris, Guillaume Le Loup, Laurent Brutus, Jean-Yves Siriez

PLOS Neglected Tropical Diseases: published May 7, 2015 | https://doi.org/10.1371/journal.pntd.0003667

Reviews

The Contributions of Onchocerciasis Control and Elimination Programs toward the Achievement of the Millennium Development Goals

Caitlin Dunn, Kelly Callahan, Moses Katabarwa, Frank Richards, Donald Hopkins, P. Craig Withers Jr., Lucas E. Buyon, Deborah McFarland

PLOS Neglected Tropical Diseases: published May 21, 2015 | https://doi.org/10.1371/journal.pntd.0003703

Prospects for Malaria Elimination in Mesoamerica and Hispaniola

Sócrates Herrera, Sergio Andrés Ochoa-Orozco, Iveth J. González, Lucrecia Peinado, Martha L. Quiñones, Myriam Arévalo-Herrera

PLOS Neglected Tropical Diseases: published May 14, 2015 | https://doi.org/10.1371/journal.pntd.0003700

A Critical Assessment of Vector Control for Dengue Prevention

Nicole L. Achee, Fred Gould, T. Alex Perkins, Robert C. Reiner Jr., Amy C. Morrison, Scott A. Ritchie, Duane J. Gubler, Remy Teyssou, Thomas W. Scott

PLOS Neglected Tropical Diseases: published May 7, 2015 | https://doi.org/10.1371/journal.pntd.0003655

Research Articles

Harnessing Case Isolation and Ring Vaccination to Control Ebola

Chad Wells, Dan Yamin, Martial L. Ndeffo-Mbah, Natasha Wenzel, Stephen G. Gaffney, Jeffrey P. Townsend, Lauren Ancel Meyers, Mosoka Fallah, Tolbert G. Nyenswah, Frederick L. Altice, Katherine E. Atkins, Alison P. Galvani

PLOS Neglected Tropical Diseases: published May 29, 2015 | https://doi.org/10.1371/journal.pntd.0003794

An Open Label Non-inferiority Trial Assessing Vibriocidal Response of a Killed Bivalent Oral Cholera Vaccine Regimen following a Five Year Interval in Kolkata, India

Suman Kanungo, Sachin N. Desai, Jayanta Saha, Ranjan Kumar Nandy, Anuradha Sinha, Deok Ryun Kim, Barnali Bannerjee, Byomkesh Manna, Jae Seung Yang, Mohammad Ali, Dipika Sur, Thomas F. Wierzba

PLOS Neglected Tropical Diseases: published May 29, 2015 | https://doi.org/10.1371/journal.pntd.0003809

A Pre-clinical Animal Model of Trypanosoma brucei Infection Demonstrating Cardiac Dysfunction

Charlotte S. McCarroll, Charlotte L. Rossor, Linda R. Morrison, Liam J. Morrison, Christopher M. Loughrey

PLOS Neglected Tropical Diseases: published May 29, 2015 | https://doi.org/10.1371/journal.pntd.0003811

Ex Vivo Host and Parasite Response to Antileishmanial Drugs and Immunomodulators

Laura Gonzalez-Fajardo, Olga Lucía Fernández, Diane McMahon-Pratt, Nancy Gore Saravia

PLOS Neglected Tropical Diseases: published May 29, 2015 | https://doi.org/10.1371/journal.pntd.0003820

Modeling the Geographic Spread of Rabies in China

Jing Chen, Lan Zou, Zhen Jin, Shigui Ruan

PLOS Neglected Tropical Diseases: published May 28, 2015 | https://doi.org/10.1371/journal.pntd.0003772

IRES-Containing VEEV Vaccine Protects Cynomolgus Macaques from IE Venezuelan Equine Encephalitis Virus Aerosol Challenge

Shannan L. Rossi, Kasi E. Russell-Lodrigue, Stephanie Z. Killeen, Eryu Wang, Grace Leal, Nicholas A. Bergren, Heather Vinet-Oliphant, Scott C. Weaver, Chad J. Roy

PLOS Neglected Tropical Diseases: published May 28, 2015 | https://doi.org/10.1371/journal.pntd.0003797

Predicting Unprecedented Dengue Outbreak Using Imported Cases and Climatic Factors in Guangzhou, 2014

Shaowei Sang, Shaohua Gu, Peng Bi, Weizhong Yang, Zhicong Yang, Lei Xu, Jun Yang, Xiaobo Liu, Tong Jiang, Haixia Wu, Cordia Chu, Qiyong Liu

PLOS Neglected Tropical Diseases: published May 28, 2015 | https://doi.org/10.1371/journal.pntd.0003808

Single Versus Double Dose Praziquantel Comparison on Efficacy and Schistosoma mansoni Re-Infection in Preschool-Age Children in Uganda: A Randomized Controlled Trial

Allen Nalugwa, Fred Nuwaha, Edridah Muheki Tukahebwa, Annette Olsen

PLOS Neglected Tropical Diseases: published May 26, 2015 | https://doi.org/10.1371/journal.pntd.0003796

Transcriptome Profiling and Genetic Study Reveal Amplified Carboxylesterase Genes Implicated in Temephos Resistance, in the Asian Tiger Mosquito Aedes albopictus

Linda Grigoraki, Jacques Lagnel, Ilias Kioulos, Anastasia Kampouraki, Evangelia Morou, Pierrick Labbé, Mylene Weill, John Vontas

PLOS Neglected Tropical Diseases: published May 22, 2015 | https://doi.org/10.1371/journal.pntd.0003771

Prevalence and Transmission of Trypanosoma cruzi in People of Rural Communities of the High Jungle of Northern Peru

Karen A. Alroy, Christine Huang, Robert H. Gilman, Victor R. Quispe-Machaca, Morgan A. Marks, Jenny Ancca-Juarez, Miranda Hillyard, Manuela Verastegui, Gerardo Sanchez, Lilia Cabrera, Elisa Vidal, Erica M. W. Billig, Vitaliano A. Cama, César Náquira, Caryn Bern, Michael Z. Levy, Working Group on Chagas Disease in Peru

PLOS Neglected Tropical Diseases: published May 22, 2015 | https://doi.org/10.1371/journal.pntd.0003779

Pan-phylum Comparison of Nematode Metabolic Potential

Rahul Tyagi, Bruce A. Rosa, Warren G. Lewis, Makedonka Mitreva

PLOS Neglected Tropical Diseases: published May 22, 2015 | https://doi.org/10.1371/journal.pntd.0003788

Competence of Cimex lectularius Bed Bugs for the Transmission of Bartonella quintana, the Agent of Trench Fever

Hamza Leulmi, Idir Bitam, Jean Michel Berenger, Hubert Lepidi, Jean Marc Rolain, Lionel Almeras, Didier Raoult, Philippe Parola

PLOS Neglected Tropical Diseases: published May 22, 2015 | https://doi.org/10.1371/journal.pntd.0003789

Drivers of Bushmeat Hunting and Perceptions of Zoonoses in Nigerian Hunting Communities

Sagan Friant, Sarah B. Paige, Tony L. Goldberg

PLOS Neglected Tropical Diseases: published May 22, 2015 | https://doi.org/10.1371/journal.pntd.0003792

The Heme Transport Capacity of LHR1 Determines the Extent of Virulence in Leishmania amazonensis

Rebecca L. Renberg, Xiaojing Yuan, Tamika K. Samuel, Danilo C. Miguel, Iqbal Hamza, Norma W. Andrews, Andrew R. Flannery

PLOS Neglected Tropical Diseases: published May 22, 2015 | https://doi.org/10.1371/journal.pntd.0003804

Urbanization of Scrub Typhus Disease in South Korea

Sang-Won Park, Na-Young Ha, Boyeong Ryu, Ji Hwan Bang, Hoyeon Song, Yuri Kim, Gwanghun Kim, Myoung-don Oh, Nam-Hyuk Cho, Jong-koo Lee

PLOS Neglected Tropical Diseases: published May 22, 2015 | https://doi.org/10.1371/journal.pntd.0003814

Parasitism in Children Aged Three Years and Under: Relationship between Infection and Growth in Rural Coastal Kenya

A. Desiree LaBeaud, Monica Nayakwadi Singer, Maxim McKibben, Peter Mungai, Eric M. Muchiri, Elisabeth McKibben, Ginny Gildengorin, Laura J. Sutherland, Charles H. King, Christopher L. King, Indu Malhotra

PLOS Neglected Tropical Diseases: published May 21, 2015 | https://doi.org/10.1371/journal.pntd.0003721

Biodistribution and Toxicity Studies of PRINT Hydrogel Nanoparticles in Mosquito Larvae and Cells

Yashdeep Phanse, Brendan M. Dunphy, Jillian L. Perry, Paul M. Airs, Cynthia C. H. Paquette, Jonathan O. Carlson, Jing Xu, J. Christopher Luft, Joseph M. DeSimone, Barry J. Beaty, Lyric C. Bartholomay

PLOS Neglected Tropical Diseases: published May 21, 2015 | https://doi.org/10.1371/journal.pntd.0003735

Biodistribution and Trafficking of Hydrogel Nanoparticles in Adult Mosquitoes

Cynthia C. H. Paquette, Yashdeep Phanse, Jillian L. Perry, Irma Sanchez-Vargas, Paul M. Airs, Brendan M. Dunphy, Jing Xu, Jonathan O. Carlson, J. Christopher Luft, Joseph M. DeSimone, Lyric C. Bartholomay, Barry J. Beaty

PLOS Neglected Tropical Diseases: published May 21, 2015 | https://doi.org/10.1371/journal.pntd.0003745

High Rates of Asymptomatic, Sub-microscopic Plasmodium vivax Infection and Disappearing Plasmodium falciparum Malaria in an Area of Low Transmission in Solomon Islands

Andreea Waltmann, Andrew W. Darcy, Ivor Harris, Cristian Koepfli, John Lodo, Ventis Vahi, David Piziki, G. Dennis Shanks, Alyssa E. Barry, Maxine Whittaker, James W. Kazura, Ivo Mueller

PLOS Neglected Tropical Diseases: published May 21, 2015 | https://doi.org/10.1371/journal.pntd.0003758

International External Quality Assessment Study for Molecular Detection of Lassa Virus

Sergejs Nikisins, Toni Rieger, Pranav Patel, Rolf Müller, Stephan Günther, Matthias Niedrig

PLOS Neglected Tropical Diseases: published May 21, 2015 | https://doi.org/10.1371/journal.pntd.0003793

Arterial Hypertension and Skin Allergy Are Risk Factors for Progression from Dengue to Dengue Hemorrhagic Fever: A Case Control Study

Maria Glória Teixeira, Enny S. Paixão, Maria da Conceição N. Costa, Rivaldo V. Cunha, Luciano Pamplona, Juarez P. Dias, Camila A. Figueiredo, Maria Aparecida A. Figueiredo, Ronald Blanton, Vanessa Morato, Maurício L. Barreto, Laura C. Rodrigues

PLOS Neglected Tropical Diseases: published May 21, 2015 | https://doi.org/10.1371/journal.pntd.0003812

Impact of Anti-Retroviral Treatment and Cotrimoxazole Prophylaxis on Helminth Infections in HIV-Infected Patients in Lambaréné, Gabon

Saskia Janssen, Sabine Hermans, Martijn Knap, Alma Moekotte, Elie G. Rossatanga, Akim A. Adegnika, Sabine Bélard, Thomas Hänscheid, Martin P. Grobusch

PLOS Neglected Tropical Diseases: published May 20, 2015 | https://doi.org/10.1371/journal.pntd.0003769

Chikungunya Virus Transmission Potential by Local Aedes Mosquitoes in the Americas and Europe

Anubis Vega-Rúa, Ricardo Lourenço-de-Oliveira, Laurence Mousson, Marie Vazeille, Sappho Fuchs, André Yébakima, Joel Gustave, Romain Girod, Isabelle Dusfour, Isabelle Leparc-Goffart, Dana L. Vanlandingham, Yan-Jang S. Huang, L. Philip Lounibos, Souand Mohamed Ali, Antoine Nougairede, Xavier de Lamballerie, Anna-Bella Failloux

PLOS Neglected Tropical Diseases: published May 20, 2015 | https://doi.org/10.1371/journal.pntd.0003780

The Epidemiology of Soil-Transmitted Helminths in Bihar State, India

Katie Greenland, Ruth Dixon, Shabbir Ali Khan, Kithsiri Gunawardena, Jimmy H. Kihara, Jennifer L. Smith, Lesley Drake, Prerna Makkar, Sri Raman, Sarman Singh, Sanjay Kumar

PLOS Neglected Tropical Diseases: published May 20, 2015 | https://doi.org/10.1371/journal.pntd.0003790

Application of RNAi to Genomic Drug Target Validation in Schistosomes

Alessandra Guidi, Nuha R. Mansour, Ross A. Paveley, Ian M. Carruthers, Jérémy Besnard, Andrew L. Hopkins, Ian H. Gilbert, Quentin D. Bickle

PLOS Neglected Tropical Diseases: published May 20, 2015 | https://doi.org/10.1371/journal.pntd.0003801

Molecular Typing of Pathogenic Leptospira Serogroup Icterohaemorrhagiae Strains Circulating in China during the Past 50 Years

Cuicai Zhang, Huimian Yang, Xiuwen Li, Zhiqiang Cao, Haijian Zhou, Linzi Zeng, Jianmin Xu, Yinghua Xu, Yung-Fu Chang, Xiaokui Guo, Yongzhang Zhu, Xiugao Jiang

PLOS Neglected Tropical Diseases: published May 19, 2015 | https://doi.org/10.1371/journal.pntd.0003762

Multiplex Real-Time PCR Assay Using TaqMan Probes for the Identification of Trypanosoma cruzi DTUs in Biological and Clinical Samples

Carolina I. Cura, Tomas Duffy, Raúl H. Lucero, Margarita Bisio, Julie Péneau, Matilde Jimenez-Coello, Eva Calabuig, María J. Gimenez, Edward Valencia Ayala, Sonia A. Kjos, José Santalla, Susan M. Mahaney, Nelly M. Cayo, Claudia Nagel, Laura Barcán, Edith S. Málaga Machaca, Karla Y. Acosta Viana, Laurent Brutus, Susana B. Ocampo, Christine Aznar, Cesar A. Cuba Cuba, Ricardo E. Gürtler, Janine M. Ramsey, Isabela Ribeiro, John L. VandeBerg, Zaida E. Yadon, Antonio Osuna, Alejandro G. Schijman

PLOS Neglected Tropical Diseases: published May 19, 2015 | https://doi.org/10.1371/journal.pntd.0003765

Killer Cell Immunoglobulin-like Receptors and Their HLA Ligands are Related with the Immunopathology of Chagas Disease

Christiane Maria Ayo, Pâmela Guimarães Reis, Márcia Machado de Oliveira Dalalio, Jeane Eliete Laguila Visentainer, Camila de Freitas Oliveira, Silvana Marques de Araújo, Divina Seila de Oliveira Marques, Ana Maria Sell

PLOS Neglected Tropical Diseases: published May 15, 2015 | https://doi.org/10.1371/journal.pntd.0003753

Insights into the Interactions of Fasciola hepatica Cathepsin L3 with a Substrate and Potential Novel Inhibitors through In Silico Approaches

Lilian Hernández Alvarez, Dany Naranjo Feliciano, Jorge Enrique Hernández González, Rosemberg de Oliveira Soares, Diego Enry Barreto Gomes, Pedro Geraldo Pascutti

PLOS Neglected Tropical Diseases: published May 15, 2015 | https://doi.org/10.1371/journal.pntd.0003759

Simvastatin and Benznidazole-Mediated Prevention of Trypanosoma cruzi-Induced Endothelial Activation: Role of 15-epi-lipoxin A4 in the Action of Simvastatin

Carolina Campos-Estrada, Ana Liempi, Fabiola González-Herrera, Michel Lapier, Ulrike Kemmerling, Barbara Pesce, Jorge Ferreira, Rodrigo López-Muñoz, Juan D. Maya

PLOS Neglected Tropical Diseases: published May 15, 2015 | https://doi.org/10.1371/journal.pntd.0003770

Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major

Jennifer Timm, Cristina Bosch-Navarrete, Eliseo Recio, Joanne E. Nettleship, Heather Rada, Dolores González-Pacanowska, Keith S. Wilson

PLOS Neglected Tropical Diseases: published May 15, 2015 | https://doi.org/10.1371/journal.pntd.0003781

Free-Roaming Dog Population Estimation and Status of the Dog Population Management and Rabies Control Program in Dhaka City, Bangladesh

Tenzin Tenzin, Rubaiya Ahmed, Nitish C. Debnath, Garba Ahmed, Mat Yamage

PLOS Neglected Tropical Diseases: published May 15, 2015 | https://doi.org/10.1371/journal.pntd.0003784

Bacterial Factors Associated with Lethal Outcome of Enteropathogenic Escherichia coli Infection: Genomic Case-Control Studies

Michael S. Donnenberg, Tracy H. Hazen, Tamer H. Farag, Sandra Panchalingam, Martin Antonio, Anowar Hossain, Inacio Mandomando, John Benjamin Ochieng, Thandavarayan Ramamurthy, Boubou Tamboura, Anita Zaidi, Myron M. Levine, Karen Kotloff, David A. Rasko, James P. Nataro

PLOS Neglected Tropical Diseases: published May 15, 2015 | https://doi.org/10.1371/journal.pntd.0003791

Sensitivity and Specificity of a Urine Circulating Anodic Antigen Test for the Diagnosis of Schistosoma haematobium in Low Endemic Settings

Stefanie Knopp, Paul L. A. M. Corstjens, Artemis Koukounari, Colin I. Cercamondi, Shaali M. Ame, Said M. Ali, Claudia J. de Dood, Khalfan A. Mohammed, Jürg Utzinger, David Rollinson, Govert J. van Dam

PLOS Neglected Tropical Diseases: published May 14, 2015 | https://doi.org/10.1371/journal.pntd.0003752

Deep Sequencing Analysis of the Ixodes ricinus Haemocytome

Michalis Kotsyfakis, Petr Kopáček, Zdeněk Franta, Joao H. F. Pedra, José M. C. Ribeiro

PLOS Neglected Tropical Diseases: published May 13, 2015 | https://doi.org/10.1371/journal.pntd.0003754

Pathogenesis of Progressive Scarring Trachoma in Ethiopia and Tanzania and Its Implications for Disease Control: Two Cohort Studies

Matthew J. Burton, Saul N. Rajak, Victor H. Hu, Athumani Ramadhani, Esmael Habtamu, Patrick Massae, Zerihun Tadesse, Kelly Callahan, Paul M. Emerson, Peng T. Khaw, David Jeffries, David C. W. Mabey, Robin L. Bailey, Helen A. Weiss, Martin J. Holland

PLOS Neglected Tropical Diseases: published May 13, 2015 | https://doi.org/10.1371/journal.pntd.0003763

Biological Control of the Chagas Disease Vector Triatoma infestans with the Entomopathogenic Fungus Beauveria bassiana Combined with an Aggregation Cue: Field, Laboratory and Mathematical Modeling Assessment

Lucas Forlani, Nicolás Pedrini, Juan R. Girotti, Sergio J. Mijailovsky, Rubén M. Cardozo, Alberto G. Gentile, Carlos M. Hernández-Suárez, Jorge E. Rabinovich, M. Patricia Juárez

PLOS Neglected Tropical Diseases: published May 13, 2015 | https://doi.org/10.1371/journal.pntd.0003778

Impact of the Use of a Rapid Diagnostic Test for Visceral Leishmaniasis on Clinical Practice in Ethiopia: A Retrospective Study

Ermias Diro, Lutgarde Lynen, Mahlet Assefa, Yegnasew Takele, Bewketu Mengesha, Emebet Adem, Rezika Mohammed, Robert Kimutai, Asrat Hailu, Marleen Boelaert, Johan van Griensven

PLOS Neglected Tropical Diseases: published May 12, 2015 | https://doi.org/10.1371/journal.pntd.0003738

An Ex Vivo Model for Studying Hepatic Schistosomiasis and the Effect of Released Protein from Dying Eggs

Geoffrey N. Gobert, Sujeevi K. Nawaratna, Marina Harvie, Grant A. Ramm, Donald P. McManus

PLOS Neglected Tropical Diseases: published May 12, 2015 | https://doi.org/10.1371/journal.pntd.0003760

Diet-Related Risk Factors for Leprosy: A Case-Control Study

Inge Wagenaar, Lisanne van Muiden, Khorshed Alam, Robert Bowers, Md. Anwar Hossain, Kolpona Kispotta, Jan Hendrik Richardus

PLOS Neglected Tropical Diseases: published May 12, 2015 | https://doi.org/10.1371/journal.pntd.0003766

Suppression of the Insulin Receptors in Adult Schistosoma japonicum Impacts on Parasite Growth and Development: Further Evidence of Vaccine Potential

Hong You, Geoffrey N. Gobert, Pengfei Cai, Rong Mou, Sujeevi Nawaratna, Guofu Fang, Francois Villinger, Donald P. McManus

PLOS Neglected Tropical Diseases: published May 11, 2015 | https://doi.org/10.1371/journal.pntd.0003730

Morphological and Molecular Descriptors of the Developmental Cycle of Babesia divergens Parasites in Human Erythrocytes

Ingrid Rossouw, Christine Maritz-Olivier, Jandeli Niemand, Riette van Biljon, Annel Smit, Nicholas A. Olivier, Lyn-Marie Birkholtz

PLOS Neglected Tropical Diseases: published May 8, 2015 | https://doi.org/10.1371/journal.pntd.0003711

Prevalence of Bacterial Febrile Illnesses in Children in Kilosa District, Tanzania

Beatrice Chipwaza, Ginethon G. Mhamphi, Steve D. Ngatunga, Majige Selemani, Mbaraka Amuri, Joseph P. Mugasa, Paul S. Gwakisa

PLOS Neglected Tropical Diseases: published May 8, 2015 | https://doi.org/10.1371/journal.pntd.0003750

Coadministration of the Three Antigenic Leishmania infantum Poly (A) Binding Proteins as a DNA Vaccine Induces Protection against Leishmania major Infection in BALB/c Mice

Manuel Soto, Laura Corvo, Esther Garde, Laura Ramírez, Virginia Iniesta, Pedro Bonay, Carlos Gómez-Nieto, Víctor M. González, M. Elena Martín, Carlos Alonso, Eduardo A. F. Coelho, Aldina Barral, Manoel Barral-Netto, Salvador Iborra

PLOS Neglected Tropical Diseases: published May 8, 2015 | https://doi.org/10.1371/journal.pntd.0003751

Deletion of Fibrinogen-like Protein 2 (FGL-2), a Novel CD4⁺ CD25⁺ Treg Effector Molecule, Leads to Improved Control of Echinococcus multilocularis Infection in Mice

Junhua Wang, Dominique A. Vuitton, Norbert Müller, Andrew Hemphill, Markus Spiliotis, Oleg Blagosklonov, Denis Grandgirard, Stephen L. Leib, Itay Shalev, Gary Levy, Xiaomei Lu, Renyong Lin, Hao Wen, Bruno Gottstein

PLOS Neglected Tropical Diseases: published May 8, 2015 | https://doi.org/10.1371/journal.pntd.0003755

Contrasting Transmission Dynamics of Co-endemic Plasmodium vivax and P. falciparum: Implications for Malaria Control and Elimination

Rintis Noviyanti, Farah Coutrier, Retno A. S. Utami, Hidayat Trimarsanto, Yusrifar K. Tirta, Leily Trianty, Andreas Kusuma, Inge Sutanto, Ayleen Kosasih, Rita Kusriastuti, William A. Hawley, Ferdinand Laihad, Neil Lobo, Jutta Marfurt, Taane G. Clark, Ric N. Price, Sarah Auburn

PLOS Neglected Tropical Diseases: published May 7, 2015 | https://doi.org/10.1371/journal.pntd.0003739

High Rate of Subclinical Chikungunya Virus Infection and Association of Neutralizing Antibody with Protection in a Prospective Cohort in The Philippines

In-Kyu Yoon, Maria Theresa Alera, Catherine B. Lago, Ilya A. Tac-An, Daisy Villa, Stefan Fernandez, Butsaya Thaisomboonsuk, Chonticha Klungthong, Jens W. Levy, John Mark Velasco, Vito G. Roque Jr., Henrik Salje, Louis R. Macareo, Laura L. Hermann, Ananda Nisalak, Anon Srikiatkhachorn

PLOS Neglected Tropical Diseases: published May 7, 2015 | https://doi.org/10.1371/journal.pntd.0003764

Cover

Trypanosoma cruzi in the Peruvian High Jungle

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