The Onchocerciasis Vaccine for Africa—TOVA—Initiative

Peter J. Hotez, Maria Elena Bottazzi, Bin Zhan, Benjamin L. Makepeace, Thomas R. Klei, David Abraham, David W. Taylor, Sara Lustigman

PLOS Neglected Tropical Diseases: published January 29, 2015 | https://doi.org/10.1371/journal.pntd.0003422

Geographic Expansion of the Invasive Mosquito Aedes albopictus across Panama—Implications for Control of Dengue and Chikungunya Viruses

Matthew J. Miller, Jose R. Loaiza

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003383

Shaping the Research Agenda

Edith Certain, Robert F. Terry, Fabio Zicker

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003350

What Have We Learned from 40 Years of Supporting Research and Capacity Building?

John C. Reeder, Jamie A. Guth

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003355

Vector Research Addressing Country Control Needs

Yeya Tiemoko Touré, Bernadette Ramirez, Johannes Sommerfeld

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003376

From Bright Ideas to Tools: The Case of Malaria

Melba F. Gomes, Annette C. Kuesel

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003377

Applied Research for Better Disease Prevention and Control

Johannes Sommerfeld, Andrew Ramsay, Franco Pagnoni, Robert F. Terry, Jamie A. Guth, John C. Reeder

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003378

A Changing Model for Developing Health Products for Poverty-Related Infectious Diseases

Piero L. Olliaro, Annette C. Kuesel, John C. Reeder

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003379

Strengthening Research Capacity—TDR's Evolving Experience in Low- and Middle-Income Countries

Olumide A. T. Ogundahunsi, Mahnaz Vahedi, Edward M. Kamau, Garry Aslanyan, Robert F. Terry, Fabio Zicker, Pascal Launois

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003380

Bilateral Conjunctivitis in a Returned Traveller

Sasha R. Fehily, Gail B. Cross, Andrew J. Fuller

PLOS Neglected Tropical Diseases: published January 15, 2015 | https://doi.org/10.1371/journal.pntd.0003351

Emergence of a New Lineage of Dengue Virus Type 2 Identified in Travelers Entering Western Australia from Indonesia, 2010-2012

Timo Ernst, Suzi McCarthy, Glenys Chidlow, Dagwin Luang-Suarkia, Edward C. Holmes, David W. Smith, Allison Imrie

PLOS Neglected Tropical Diseases: published January 30, 2015 | https://doi.org/10.1371/journal.pntd.0003442

Classification of Bartonella Strains Associated with Straw-Colored Fruit Bats (Eidolon helvum) across Africa Using a Multi-locus Sequence Typing Platform

Ying Bai, David T. S. Hayman, Clifton D. McKee, Michael Y. Kosoy

PLOS Neglected Tropical Diseases: published January 30, 2015 | https://doi.org/10.1371/journal.pntd.0003478

Development and Validation of a Luminescence-based, Medium-Throughput Assay for Drug Screening in Schistosoma mansoni

Cristiana Lalli, Alessandra Guidi, Nadia Gennari, Sergio Altamura, Alberto Bresciani, Giovina Ruberti

PLOS Neglected Tropical Diseases: published January 30, 2015 | https://doi.org/10.1371/journal.pntd.0003484

A Cross-Sectional Study of ‘Yaws’ in Districts of Ghana Which Have Previously Undertaken Azithromycin Mass Drug Administration for Trachoma Control

Rosanna Ghinai, Philip El-Duah, Kai-Hua Chi, Allan Pillay, Anthony W. Solomon, Robin L. Bailey, Nsiire Agana, David C. W. Mabey, Cheng-Yen Chen, Yaw Adu-Sarkodie, Michael Marks

PLOS Neglected Tropical Diseases: published January 29, 2015 | https://doi.org/10.1371/journal.pntd.0003496

Leishmania (L.) mexicana Infected Bats in Mexico: Novel Potential Reservoirs

Miriam Berzunza-Cruz, Ángel Rodríguez-Moreno, Gabriel Gutiérrez-Granados, Constantino González-Salazar, Christopher R. Stephens, Mircea Hidalgo-Mihart, Carlos F. Marina, Eduardo A. Rebollar-Téllez, Dulce Bailón-Martínez, Cristina Domingo Balcells, Carlos N. Ibarra-Cerdeña, Víctor Sánchez-Cordero, Ingeborg Becker

PLOS Neglected Tropical Diseases: published January 28, 2015 | https://doi.org/10.1371/journal.pntd.0003438

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Conservation and Immunogenicity of Novel Antigens in Diverse Isolates of Enterotoxigenic Escherichia coli

Qingwei Luo, Firdausi Qadri, Rita Kansal, David A. Rasko, Alaullah Sheikh, James M. Fleckenstein

PLOS Neglected Tropical Diseases: published January 28, 2015 | https://doi.org/10.1371/journal.pntd.0003446

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Automated High-Content Assay for Compounds Selectively Toxic to Trypanosoma cruzi in a Myoblastic Cell Line

Julio Alonso-Padilla, Ignacio Cotillo, Jesús L. Presa, Juan Cantizani, Imanol Peña, Ana I. Bardera, Jose J. Martín, Ana Rodriguez

PLOS Neglected Tropical Diseases: published January 23, 2015 | https://doi.org/10.1371/journal.pntd.0003493

Discovery of Mosquito Saliva MicroRNAs during CHIKV Infection

Payal D. Maharaj, Steven G. Widen, Jing Huang, Thomas G. Wood, Saravanan Thangamani

PLOS Neglected Tropical Diseases: published January 22, 2015 | https://doi.org/10.1371/journal.pntd.0003386

Source Tracking Mycobacterium ulcerans Infections in the Ashanti Region, Ghana

Charles A. Narh, Lydia Mosi, Charles Quaye, Christelle Dassi, Daniele O. Konan, Samuel C. K. Tay, Dziedzom K. de Souza, Daniel A. Boakye, Bassirou Bonfoh

PLOS Neglected Tropical Diseases: published January 22, 2015 | https://doi.org/10.1371/journal.pntd.0003437

The Influence of HIV and Schistosomiasis on Renal Function: A Cross-sectional Study among Children at a Hospital in Tanzania

Neema M. Kayange, Luke R. Smart, Jennifer A. Downs, Mwanaisha Maskini, Daniel W. Fitzgerald, Robert N. Peck

PLOS Neglected Tropical Diseases: published January 22, 2015 | https://doi.org/10.1371/journal.pntd.0003472

Real-time PCR Demonstrates High Prevalence of Schistosoma japonicum in the Philippines: Implications for Surveillance and Control

Catherine. A. Gordon, Luz P. Acosta, Geoffrey N. Gobert, Remigio M. Olveda, Allen G. Ross, Gail M. Williams, Darren J. Gray, Donald Harn, Yuesheng Li, Donald P. McManus

PLOS Neglected Tropical Diseases: published January 21, 2015 | https://doi.org/10.1371/journal.pntd.0003483

Microsatellite Alterations Are also Present in the Less Aggressive Types of Adult T-Cell Leukemia-Lymphoma

Marcelo Magalhães, Pedro D. Oliveira, Achiléa L. Bittencourt, Lourdes Farre

PLOS Neglected Tropical Diseases: published January 15, 2015 | https://doi.org/10.1371/journal.pntd.0003403

Male Mosquitoes as Vehicles for Insecticide

James W. Mains, Corey L. Brelsfoard, Stephen L. Dobson

PLOS Neglected Tropical Diseases: published January 15, 2015 | https://doi.org/10.1371/journal.pntd.0003406

Household Costs of Leprosy Reactions (ENL) in Rural India

David J. Chandler, Kristian S. Hansen, Bhabananda Mahato, Joydeepa Darlong, Annamma John, Diana N. J. Lockwood

PLOS Neglected Tropical Diseases: published January 15, 2015 | https://doi.org/10.1371/journal.pntd.0003431

Th17 Down-regulation Is Involved in Reduced Progression of Schistosomiasis Fibrosis in ICOSL KO Mice

Bo Wang, Song Liang, Yu Wang, Xing-Quan Zhu, Wei Gong, Hui-Qin Zhang, Ying Li, Chao-Ming Xia

PLOS Neglected Tropical Diseases: published January 15, 2015 | https://doi.org/10.1371/journal.pntd.0003434

Associations between Schistosomiasis and the Use of Human Waste as an Agricultural Fertilizer in China

Elizabeth J. Carlton, Yang Liu, Bo Zhong, Alan Hubbard, Robert C. Spear

PLOS Neglected Tropical Diseases: published January 15, 2015 | https://doi.org/10.1371/journal.pntd.0003444

Effect of Antenatal Parasitic Infections on Anti-vaccine IgG Levels in Children: A Prospective Birth Cohort Study in Kenya

Indu Malhotra, Maxim McKibben, Peter Mungai, Elisabeth McKibben, Xuelei Wang, Laura J. Sutherland, Eric M. Muchiri, Charles H. King, Christopher L. King, A. Desiree LaBeaud

PLOS Neglected Tropical Diseases: published January 15, 2015 | https://doi.org/10.1371/journal.pntd.0003466

Bartonella spp. Bacteremia in Blood Donors from Campinas, Brazil

Luiza Helena Urso Pitassi, Pedro Paulo Vissotto de Paiva Diniz, Diana Gerardi Scorpio, Marina Rovani Drummond, Bruno Grosselli Lania, Maria Lourdes Barjas-Castro, Rovilson Gilioli, Silvia Colombo, Stanley Sowy, Edward B. Breitschwerdt, William L. Nicholson, Paulo Eduardo Neves Ferreira Velho

PLOS Neglected Tropical Diseases: published January 15, 2015 | https://doi.org/10.1371/journal.pntd.0003467

Characterization of Plasmodium ovale curtisi and P. ovale wallikeri in Western Kenya Utilizing a Novel Species-specific Real-time PCR Assay

Robin H. Miller, Clifford O. Obuya, Elizabeth W. Wanja, Bernhards Ogutu, John Waitumbi, Shirley Luckhart, V. Ann Stewart

PLOS Neglected Tropical Diseases: published January 15, 2015 | https://doi.org/10.1371/journal.pntd.0003469

Th1-Biased Immunomodulation and Therapeutic Potential of Artemisia annua in Murine Visceral Leishmaniasis

Mohammad Islamuddin, Garima Chouhan, Abdullah Farooque, Bilikere S. Dwarakanath, Dinkar Sahal, Farhat Afrin

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003321

Pyrethroid-Resistance and Presence of Two Knockdown Resistance (kdr) Mutations, F1534C and a Novel Mutation T1520I, in Indian Aedes aegypti

Raja Babu S. Kushwah, Cherry L. Dykes, Neera Kapoor, Tridibes Adak, Om P. Singh

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003332

Mycobacterium africanum Is Associated with Patient Ethnicity in Ghana

Adwoa Asante-Poku, Dorothy Yeboah-Manu, Isaac Darko Otchere, Samuel Y. Aboagye, David Stucki, Jan Hattendorf, Sonia Borrell, Julia Feldmann, Emelia Danso, Sebastien Gagneux

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003370

Peptidases Compartmentalized to the Ascaris suum Intestinal Lumen and Apical Intestinal Membrane

Douglas P. Jasmer, Bruce A. Rosa, Makedonka Mitreva

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003375

Cost-effectiveness of Antivenoms for Snakebite Envenoming in Nigeria

Abdulrazaq G. Habib, Mohammed Lamorde, Mahmood M. Dalhat, Zaiyad G. Habib, Andreas Kuznik

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003381

Modelling the Effects of Seasonality and Socioeconomic Impact on the Transmission of Rift Valley Fever Virus

Yanyu Xiao, John C. Beier, Robert Stephen Cantrell, Chris Cosner, Donald L. DeAngelis, Shigui Ruan

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003388

Invasive Salmonella Typhimurium ST313 with Naturally Attenuated Flagellin Elicits Reduced Inflammation and Replicates within Macrophages

Girish Ramachandran, Darren J. Perkins, Patrick J. Schmidlein, Mohan E. Tulapurkar, Sharon M. Tennant

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003394

Using Modelling to Disentangle the Relative Contributions of Zoonotic and Anthroponotic Transmission: The Case of Lassa Fever

Giovanni Lo Iacono, Andrew A. Cunningham, Elisabeth Fichet-Calvet, Robert F. Garry, Donald S. Grant, Sheik Humarr Khan, Melissa Leach, Lina M. Moses, John S. Schieffelin, Jeffrey G. Shaffer, Colleen T. Webb, James L. N. Wood

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003398

Genome and Phylogenetic Analyses of Trypanosoma evansi Reveal Extensive Similarity to T. brucei and Multiple Independent Origins for Dyskinetoplasty

Jason Carnes, Atashi Anupama, Oliver Balmer, Andrew Jackson, Michael Lewis, Rob Brown, Igor Cestari, Marc Desquesnes, Claire Gendrin, Christiane Hertz-Fowler, Hideo Imamura, Alasdair Ivens, Luděk Kořený, De-Hua Lai, Annette MacLeod, Suzanne M. McDermott, Chris Merritt, Severine Monnerat, Wonjong Moon, Peter Myler, Isabelle Phan, Gowthaman Ramasamy, Dhileep Sivam, Zhao-Rong Lun, Julius Lukeš, Ken Stuart, Achim Schnaufer

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003404

Systematic Review of Sub-microscopic P. vivax Infections: Prevalence and Determining Factors

Qin Cheng, Jane Cunningham, Michelle L. Gatton

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003413

Hyperreactive Onchocerciasis is Characterized by a Combination of Th17-Th2 Immune Responses and Reduced Regulatory T Cells

Gnatoulma Katawa, Laura E. Layland, Alex Y. Debrah, Charlotte von Horn, Linda Batsa, Alexander Kwarteng, Sandra Arriens, David W. Taylor, Sabine Specht, Achim Hoerauf, Tomabu Adjobimey

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003414

Burden of Disease Measured by Disability-Adjusted Life Years and a Disease Forecasting Time Series Model of Scrub Typhus in Laiwu, China

Li-Ping Yang, Si-Yuan Liang, Xian-Jun Wang, Xiu-Jun Li, Yan-Ling Wu, Wei Ma

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003420

Reduction of Urogenital Schistosomiasis with an Integrated Control Project in Sudan

Young-Ha Lee, Hoo Gn Jeong, Woo Hyun Kong, Soon-Hyung Lee, Han-Ik Cho, Hae-Sung Nam, Hassan Ahmed Hassan Ahmed Ismail, Gibril Nouman Abd Alla, Chung Hyeon Oh, Sung-Tae Hong

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003423

Improving Serodiagnosis of Human and Canine Leishmaniasis with Recombinant Leishmania braziliensis Cathepsin L-like Protein and a Synthetic Peptide Containing Its Linear B-cell Epitope

Daniel Menezes-Souza, Tiago Antônio de Oliveira Mendes, Matheus de Souza Gomes, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003426

Metabolic Responses to Orientia tsutsugamushi Infection in a Mouse Model

Jeeyoun Jung, Youngae Jung, Byoungchul Gill, Changhun Kim, Kyu-Jam Hwang, Young-Ran Ju, Hye-Ja Lee, Hyuk Chu, Geum-Sook Hwang

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003427

Novel Recombinant Multiepitope Proteins for the Diagnosis of Asymptomatic Leishmania infantum-Infected Dogs

Angélica Rosa Faria, Luciano de Castro Veloso, Wendel Coura-Vital, Alexandre Barbosa Reis, Leonardo Miranda Damasceno, Ricardo T. Gazzinelli, Hélida M. Andrade

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003429

Ribose 5-Phosphate Isomerase B Knockdown Compromises Trypanosoma brucei Bloodstream Form Infectivity

Inês Loureiro, Joana Faria, Christine Clayton, Sandra Macedo-Ribeiro, Nuno Santarém, Nilanjan Roy, Anabela Cordeiro-da-Siva, Joana Tavares

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003430

Low Frequency of Circulating CD8⁺ T Stem Cell Memory Cells in Chronic Chagasic Patients with Severe Forms of the Disease

Jose Mateus, Paola Lasso, Paula Pavia, Fernando Rosas, Nubia Roa, Carlos Andrés Valencia-Hernández, John Mario González, Concepción J. Puerta, Adriana Cuéllar

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003432

Host-Seeking Behavior and Dispersal of Triatoma infestans, a Vector of Chagas Disease, under Semi-field Conditions

Ricardo Castillo-Neyra, Corentin M. Barbu, Renzo Salazar, Katty Borrini, Cesar Naquira, Michael Z. Levy

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003433

In Silico Repositioning-Chemogenomics Strategy Identifies New Drugs with Potential Activity against Multiple Life Stages of Schistosoma mansoni

Bruno J. Neves, Rodolpho C. Braga, José C. B. Bezerra, Pedro V. L. Cravo, Carolina H. Andrade

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003435

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Intranasal Vaccination with Leishmanial Antigens Protects Golden Hamsters (Mesocricetus auratus) Against Leishmania (Viannia) braziliensis Infection

Luzinei da Silva-Couto, Raquel Peralva Ribeiro-Romão, Andrea Franco Saavedra, Beatriz Lilian da Silva Costa Souza, Otacílio Cruz Moreira, Adriano Gomes-Silva, Bartira Rossi-Bergmann, Alda Maria Da-Cruz, Eduardo Fonseca Pinto

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003439

Epidemiology of Cholera in the Philippines

Anna Lena Lopez, Lino Y. Macasaet, Michelle Ylade, Enrique A. Tayag, Mohammad Ali

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003440

Type 3 Secretion System Cluster 3 Is a Critical Virulence Determinant for Lung-Specific Melioidosis

Maria G. Gutierrez, Tia L. Pfeffer, Jonathan M. Warawa

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003441

Buruli Ulcer in South Western Nigeria: A Retrospective Cohort Study of Patients Treated in Benin

Estelle Marion, Kevin Carolan, Ambroise Adeye, Marie Kempf, Annick Chauty, Laurent Marsollier

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003443

Sero-Prevalence and Cross-Reactivity of Chikungunya Virus Specific Anti-E2EP3 Antibodies in Arbovirus-Infected Patients

Yiu-Wing Kam, Kwoon-Yong Pok, Kai Er Eng, Li-Kiang Tan, Simrandeep Kaur, Wendy W. L. Lee, Yee-Sin Leo, Lee-Ching Ng, Lisa F. P. Ng

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003445

Tsetse GmmSRPN10 Has Anti-complement Activity and Is Important for Successful Establishment of Trypanosome Infections in the Fly Midgut

Cher-Pheng Ooi, Lee R. Haines, Daniel M. Southern, Michael J. Lehane, Alvaro Acosta-Serrano

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003448

Identification of Human Semiochemicals Attractive to the Major Vectors of Onchocerciasis

Ryan M. Young, Nathan D. Burkett-Cadena, Tommy W. McGaha Jr, Mario A. Rodriguez-Perez, Laurent D. Toé, Monsuru A. Adeleke, Moussa Sanfo, Traore Soungalo, Charles R. Katholi, Raymond Noblet, Henry Fadamiro, Jose L. Torres-Estrada, Mario C. Salinas-Carmona, Bill Baker, Thomas R. Unnasch, Eddie W. Cupp

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003450

Aptamer-Based Detection of Disease Biomarkers in Mouse Models for Chagas Drug Discovery

Fernanda Fortes de Araujo, Rana Nagarkatti, Charu Gupta, Ana Paula Marino, Alain Debrabant

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003451

Evaluation of the Loop Mediated Isothermal DNA Amplification (LAMP) Kit for Malaria Diagnosis in P. vivax Endemic Settings of Colombia

Andrés F. Vallejo, Nora L. Martínez, Iveth J. González, Myriam Arévalo-Herrera, Sócrates Herrera

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003453

Effectiveness of Routine BCG Vaccination on Buruli Ulcer Disease: A Case-Control Study in the Democratic Republic of Congo, Ghana and Togo

Richard Odame Phillips, Delphin Mavinga Phanzu, Marcus Beissner, Kossi Badziklou, Elysée Kalundieko Luzolo, Fred Stephen Sarfo, Wemboo Afiwa Halatoko, Yaw Amoako, Michael Frimpong, Abass Mohammed Kabiru, Ebekalisai Piten, Issaka Maman, Bawimodom Bidjada, Adjaho Koba, Koffi Somenou Awoussi, Basile Kobara, Jörg Nitschke, Franz Xaver Wiedemann, Abiba Banla Kere, Ohene Adjei, Thomas Löscher, Bernhard Fleischer, Gisela Bretzel, Karl-Heinz Herbinger

PLOS Neglected Tropical Diseases: published January 8, 2015 | https://doi.org/10.1371/journal.pntd.0003457