United States Military Tropical Medicine: Extraordinary Legacy, Uncertain Future

Coreen M. Beaumier, Ana Maria Gomez-Rubio, Peter J. Hotez, Peter J. Weina

PLOS Neglected Tropical Diseases: published December 26, 2013 | https://doi.org/10.1371/journal.pntd.0002448

Scrub Typhus in Mainland China, 2006–2012: The Need for Targeted Public Health Interventions

Wen-Yi Zhang, Li-Ya Wang, Fan Ding, Wen-Biao Hu, Ricardo J. Soares Magalhaes, Hai-Long Sun, Yun-Xi Liu, Qi-Yong Liu, Liu-Yu Huang, Archie C. A. Clements, Shen-Long Li, Cheng-Yi Li

PLOS Neglected Tropical Diseases: published December 26, 2013 | https://doi.org/10.1371/journal.pntd.0002493

Dengue Research Funded by the European Commission-Scientific Strategies of Three European Dengue Research Consortia

Thomas Jaenisch, IDAMS, Anavaj Sakuntabhai, DENFREE, Annelies Wilder-Smith, DengueTools

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002320

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MDGs and NTDs: Reshaping the Global Health Agenda

James Smith, Emma Michelle Taylor

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002529

Two Women Presenting Worsening Cutaneous Ulcers during Pregnancy: Diagnosis, Immune Response, and Follow-up

Fátima Conceição-Silva, Fernanda Nazaré Morgado, Maria Inês Fernandes Pimentel, Erica de Camargo Ferreira e Vasconcellos, Armando O. Schubach, Cláudia M. Valete-Rosalino, Pascale Kropf, Ingrid Müller

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002472

Tapeworm Diphyllobothrium dendriticum (Cestoda)—Neglected or Emerging Human Parasite?

Roman Kuchta, Jan Brabec, Petra Kubáčková, Tomáš Scholz

PLOS Neglected Tropical Diseases: published December 26, 2013 | https://doi.org/10.1371/journal.pntd.0002535

Detection of Serotype-Specific Antibodies to the Four Dengue Viruses Using an Immune Complex Binding (ICB) ELISA

Petra Emmerich, Angela Mika, Herbert Schmitz

PLOS Neglected Tropical Diseases: published December 26, 2013 | https://doi.org/10.1371/journal.pntd.0002580

Micro-Geographical Heterogeneity in Schistosoma mansoni and S. haematobium Infection and Morbidity in a Co-Endemic Community in Northern Senegal

Lynn Meurs, Moustapha Mbow, Nele Boon, Frederik van den Broeck, Kim Vereecken, Tandakha Ndiaye Dièye, Emmanuel Abatih, Tine Huyse, Souleymane Mboup, Katja Polman

PLOS Neglected Tropical Diseases: published December 26, 2013 | https://doi.org/10.1371/journal.pntd.0002608

Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever

Brian B. Gowen, Terry L. Juelich, Eric J. Sefing, Trevor Brasel, Jennifer K. Smith, Lihong Zhang, Bersabeh Tigabu, Terence E. Hill, Tatyana Yun, Colette Pietzsch, Yousuke Furuta, Alexander N. Freiberg

PLOS Neglected Tropical Diseases: published December 26, 2013 | https://doi.org/10.1371/journal.pntd.0002614

Epidemiological Trends of Dengue Disease in Brazil (2000–2010): A Systematic Literature Search and Analysis

Maria Glória Teixeira, João Bosco Siqueira, Jr, Germano L. C. Ferreira, Lucia Bricks, Graham Joint

PLOS Neglected Tropical Diseases: published December 19, 2013 | https://doi.org/10.1371/journal.pntd.0002520

Revisiting the Central Metabolism of the Bloodstream Forms of Trypanosoma brucei: Production of Acetate in the Mitochondrion Is Essential for Parasite Viability

Muriel Mazet, Pauline Morand, Marc Biran, Guillaume Bouyssou, Pierrette Courtois, Sylvie Daulouède, Yoann Millerioux, Jean-Michel Franconi, Philippe Vincendeau, Patrick Moreau, Frédéric Bringaud

PLOS Neglected Tropical Diseases: published December 19, 2013 | https://doi.org/10.1371/journal.pntd.0002587

Praziquantel Treatment Decreases Schistosoma mansoni Genetic Diversity in Experimental Infections

Regina Coeli, Elio H. Baba, Neusa Araujo, Paulo M. Z. Coelho, Guilherme Oliveira

PLOS Neglected Tropical Diseases: published December 19, 2013 | https://doi.org/10.1371/journal.pntd.0002596

Rapid, Serial, Non-invasive Assessment of Drug Efficacy in Mice with Autoluminescent Mycobacterium ulcerans Infection

Tianyu Zhang, Si-Yang Li, Paul J. Converse, Jacques H. Grosset, Eric L. Nuermberger

PLOS Neglected Tropical Diseases: published December 19, 2013 | https://doi.org/10.1371/journal.pntd.0002598

The Cytokine and Chemokine Profiles in Patients with Hand, Foot and Mouth Disease of Different Severities in Shanghai, China, 2010

Mei Zeng, Xiaoyan Zheng, Ruicheng Wei, Na Zhang, Kai Zhu, Bin Xu, Chun-Hui Yang, Chun-Fu Yang, Chaoyang Deng, Dongbo Pu, Xiaohong Wang, Ralf Altmeyer, Qibin Leng

PLOS Neglected Tropical Diseases: published December 19, 2013 | https://doi.org/10.1371/journal.pntd.0002599

Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus

Chad E. Mire, Joan B. Geisbert, Andrea Marzi, Krystle N. Agans, Heinz Feldmann, Thomas W. Geisbert

PLOS Neglected Tropical Diseases: published December 19, 2013 | https://doi.org/10.1371/journal.pntd.0002600

Septins of Platyhelminths: Identification, Phylogeny, Expression and Localization among Developmental Stages of Schistosoma mansoni

Ana E. Zeraik, Gabriel Rinaldi, Victoria H. Mann, Anastas Popratiloff, Ana P. U. Araujo, Ricardo DeMarco, Paul J. Brindley

PLOS Neglected Tropical Diseases: published December 19, 2013 | https://doi.org/10.1371/journal.pntd.0002602

Molecular Characterization of Severin from Clonorchis sinensis Excretory/Secretory Products and Its Potential Anti-apoptotic Role in Hepatocarcinoma PLC Cells

Xueqing Chen, Shan Li, Lei He, Xiaoyun Wang, Pei Liang, Wenjun Chen, Meng Bian, Mengyu Ren, Jinsi Lin, Chi Liang, Jin Xu, Zhongdao Wu, Xuerong Li, Yan Huang, Xinbing Yu

PLOS Neglected Tropical Diseases: published December 19, 2013 | https://doi.org/10.1371/journal.pntd.0002606

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Laboratory-Based Prospective Surveillance for Community Outbreaks of Shigella spp. in Argentina

María R. Viñas, Ezequiel Tuduri, Alicia Galar, Katherine Yih, Mariana Pichel, John Stelling, Silvina P. Brengi, Anabella Della Gaspera, Claudia van der Ploeg, Susana Bruno, Ariel Rogé, María I. Caffer, Martin Kulldorff, Marcelo Galas, Group MIDAS - Argentina

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002521

Venezuelan Equine Encephalitis Viruses (VEEV) in Argentina: Serological Evidence of Human Infection

María Belén Pisano, Griselda Oria, Geraldine Beskow, Javier Aguilar, Brenda Konigheim, María Luisa Cacace, Luis Aguirre, Marina Stein, Marta Silvia Contigiani

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002551

New Insights into the Molecular Epidemiology and Population Genetics of Schistosoma mansoni in Ugandan Pre-school Children and Mothers

Martha Betson, Jose C. Sousa-Figueiredo, Narcis B. Kabatereine, J. Russell Stothard

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002561

Geographic Variation in Access to Dog-Bite Care in Pakistan and Risk of Dog-Bite Exposure in Karachi: Prospective Surveillance Using a Low-Cost Mobile Phone System

Syed Mohammad Asad Zaidi, Alain B. Labrique, Saira Khowaja, Ismat Lotia-Farrukh, Julia Irani, Naseem Salahuddin, Aamir Javed Khan

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002574

Polyfunctional T Cell Responses in Children in Early Stages of Chronic Trypanosoma cruzi Infection Contrast with Monofunctional Responses of Long-term Infected Adults

María C. Albareda, Ana M. De Rissio, Gonzalo Tomas, Alicia Serjan, María G. Alvarez, Rodolfo Viotti, Laura E. Fichera, Mónica I. Esteva, Daniel Potente, Alejandro Armenti, Rick L. Tarleton, Susana A. Laucella

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002575

Ecology and Geography of Transmission of Two Bat-Borne Rabies Lineages in Chile

Luis E. Escobar, A. Townsend Peterson, Myriam Favi, Verónica Yung, Daniel J. Pons, Gonzalo Medina-Vogel

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002577

Community Acceptance of Tsetse Control Baits: A Qualitative Study in Arua District, North West Uganda

Vanja Kovacic, Inaki Tirados, Johan Esterhuizen, Clement T. N. Mangwiro, Stephen J. Torr, Michael J. Lehane, Helen Smith

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002579

Cutaneous Distribution and Circadian Rhythm of Onchocerca lupi Microfilariae in Dogs

Domenico Otranto, Filipe Dantas-Torres, Alessio Giannelli, Francesca Abramo, Aleksandra Ignjatović Ćupina, Dušan Petrić, Luís Cardoso, Yasen Mutafchiev, Helder Cortes

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002585

Impact of Six Rounds of Mass Drug Administration on Brugian Filariasis and Soil-Transmitted Helminth Infections in Eastern Indonesia

Taniawati Supali, Yenny Djuardi, Mark Bradley, Rahmah Noordin, Paul Rückert, Peter U. Fischer

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002586

Temporal Patterns of Abundance of Aedes aegypti and Aedes albopictus (Diptera: Culicidae) and Mitochondrial DNA Analysis of Ae. albopictus in the Central African Republic

Basile Kamgang, Carine Ngoagouni, Alexandre Manirakiza, Emmanuel Nakouné, Christophe Paupy, Mirdad Kazanji

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002590

Private Selective Sweeps Identified from Next-Generation Pool-Sequencing Reveal Convergent Pathways under Selection in Two Inbred Schistosoma mansoni Strains

Julie A. J. Clément, Eve Toulza, Mathieu Gautier, Hugues Parrinello, David Roquis, Jérôme Boissier, Anne Rognon, Hélène Moné, Gabriel Mouahid, Jérôme Buard, Guillaume Mitta, Christoph Grunau

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002591

Corticosteroids for Dengue – Why Don't They Work?

Thi Hanh Tien Nguyen, Than Ha Quyen Nguyen, Tuan Trung Vu, Jeremy Farrar, Truong Long Hoang, Thi Hoai Tam Dong, Van Ngoc Tran, Khanh Lam Phung, Marcel Wolbers, Stephen S. Whitehead, Martin L. Hibberd, Bridget Wills, Cameron P. Simmons

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002592

Comparative Clinical Study of Different Multiplex Real Time PCR Strategies for the Simultaneous Differential Diagnosis between Extrapulmonary Tuberculosis and Focal Complications of Brucellosis

Rocio Sanjuan-Jimenez, Pilar Morata, Pilar Bermúdez, M. José Bravo, Juan D. Colmenero

PLOS Neglected Tropical Diseases: published December 12, 2013 | https://doi.org/10.1371/journal.pntd.0002593

Over-Expression of 60s Ribosomal L23a Is Associated with Cellular Proliferation in SAG Resistant Clinical Isolates of Leishmania donovani

Sanchita Das, Priyanka Shah, Rajendra K. Baharia, Rati Tandon, Prashant Khare, Shyam Sundar, Amogh A. Sahasrabuddhe, M. I. Siddiqi, Anuradha Dube

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002527

The Burden of Cholera in Uganda

Godfrey Bwire, Mugagga Malimbo, Brian Maskery, Young Eun Kim, Vittal Mogasale, Ann Levin

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002545

On-Chip Imaging of Schistosoma haematobium Eggs in Urine for Diagnosis by Computer Vision

Ewert Linder, Anne Grote, Sami Varjo, Nina Linder, Marianne Lebbad, Mikael Lundin, Vinod Diwan, Jari Hannuksela, Johan Lundin

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002547

Biochemical Diversity in the Trypanosoma congolense Trans-sialidase Family

Thaddeus T. Gbem, Mario Waespy, Bettina Hesse, Frank Dietz, Joel Smith, Gloria D. Chechet, Jonathan A. Nok, Sørge Kelm

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002549

Individual Correlates of Podoconiosis in Areas of Varying Endemicity: A Case-Control Study

Yordanos B. Molla, Jennifer S. Le Blond, Nicola Wardrop, Peter Baxter, Peter M. Atkinson, Melanie J. Newport, Gail Davey

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002554

Soulamarin Isolated from Calophyllum brasiliense (Clusiaceae) Induces Plasma Membrane Permeabilization of Trypanosoma cruzi and Mytochondrial Dysfunction

Alexandre Rea, Andre G. Tempone, Erika G. Pinto, Juliana T. Mesquita, Eliana Rodrigues, Luciana Grus M. Silva, Patricia Sartorelli, João Henrique G. Lago

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002556

Elimination and Eradication of Neglected Tropical Diseases with Mass Drug Administrations: A Survey of Experts

Jeremy D. Keenan, Peter J. Hotez, Abdou Amza, Nicole E. Stoller, Bruce D. Gaynor, Travis C. Porco, Thomas M. Lietman

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002562

Burden of Mycobacterium ulcerans Disease (Buruli Ulcer) and the Underreporting Ratio in the Territory of Songololo, Democratic Republic of Congo

Delphin Mavinga Phanzu, Patrick Suykerbuyk, Paul Saunderson, Philippe Ngwala Lukanu, Jean-Bedel Masamba Minuku, Désiré Bofunga B. Imposo, Blanchard Mbadu Diengidi, Makanzu Kayinua, Jean-Jacques Tamfum Muyembe, Pascal Tshindele Lutumba, Bouke C. de Jong, Françoise Portaels, Marleen Boelaert

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002563

Canada's Neglected Tropical Disease Research Network: Who's in the Core—Who's on the Periphery?

Kaye Phillips, Jillian Clare Kohler, Peter Pennefather, Halla Thorsteinsdottir, Joseph Wong

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002568

De Novo Assembly of a Field Isolate Genome Reveals Novel Plasmodium vivax Erythrocyte Invasion Genes

James Hester, Ernest R. Chan, Didier Menard, Odile Mercereau-Puijalon, John Barnwell, Peter A. Zimmerman, David Serre

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002569

Characteristics of the Human Host Have Little Influence on Which Local Schistosoma mansoni Populations Are Acquired

Lúcio M. Barbosa, Luciano K. Silva, Eliana A. Reis, Theomira M. Azevedo, Jackson M. Costa, Walter A. Blank, Mitermayer G. Reis, Ronald E. Blanton

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002572

Molecular Identification of Nocardia Isolates from Clinical Samples and an Overview of Human Nocardiosis in Brazil

Paulo Victor Pereira Baio, Juliana Nunes Ramos, Louisy Sanches dos Santos, Morgana Fonseca Soriano, Elisa Martins Ladeira, Mônica Cristina Souza, Thereza Cristina Ferreira Camello, Marcio Garcia Ribeiro, Raphael Hirata Junior, Verônica Viana Vieira, Ana Luíza Mattos-Guaraldi

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002573

Knockdown of Asparagine Synthetase A Renders Trypanosoma brucei Auxotrophic to Asparagine

Inês Loureiro, Joana Faria, Christine Clayton, Sandra Macedo Ribeiro, Nilanjan Roy, Nuno Santarém, Joana Tavares, Anabela Cordeiro-da-Silva

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002578

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Dengue Virus in Sub-tropical Northern and Central Viet Nam: Population Immunity and Climate Shape Patterns of Viral Invasion and Maintenance

Maia A. Rabaa, Cameron P. Simmons, Annette Fox, Mai Quynh Le, Thuy Thi Thu Nguyen, Hai Yen Le, Robert V. Gibbons, Xuyen Thanh Nguyen, Edward C. Holmes, John G. Aaskov

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002581

Geographic Distribution and Genetic Characterization of Lassa Virus in Sub-Saharan Mali

David Safronetz, Nafomon Sogoba, Job E. Lopez, Ousmane Maiga, Eric Dahlstrom, Marko Zivcec, Friederike Feldmann, Elaine Haddock, Robert J. Fischer, Jennifer M. Anderson, Vincent J. Munster, Luis Branco, Robert Garry, Stephen F. Porcella, Tom G. Schwan, Heinz Feldmann

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002582

Transmission Assessment Surveys (TAS) to Define Endpoints for Lymphatic Filariasis Mass Drug Administration: A Multicenter Evaluation

Brian K. Chu, Michael Deming, Nana-Kwadwo Biritwum, Windtaré R. Bougma, Améyo M. Dorkenoo, Maged El-Setouhy, Peter U. Fischer, Katherine Gass, Manuel Gonzalez de Peña, Leda Mercado-Hernandez, Dominique Kyelem, Patrick J. Lammie, Rebecca M. Flueckiger, Upendo J. Mwingira, Rahmah Noordin, Irene Offei Owusu, Eric A. Ottesen, Alexandre Pavluck, Nils Pilotte, Ramakrishna U. Rao, Dilhani Samarasekera, Mark A. Schmaedick, Sunil Settinayake, Paul E. Simonsen, Taniawati Supali, Fasihah Taleo, Melissa Torres, Gary J. Weil, Kimberly Y. Won

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002584

The Intestinal Expulsion of the Roundworm Ascaris suum Is Associated with Eosinophils, Intra-Epithelial T Cells and Decreased Intestinal Transit Time

Dries Masure, Tao Wang, Johnny Vlaminck, Sarah Claerhoudt, Koen Chiers, Wim Van den Broeck, Jimmy Saunders, Jozef Vercruysse, Peter Geldhof

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002588

Estimating Leptospirosis Incidence Using Hospital-Based Surveillance and a Population-Based Health Care Utilization Survey in Tanzania

Holly M. Biggs, Julian T. Hertz, O. Michael Munishi, Renee L. Galloway, Florian Marks, Wilbrod Saganda, Venance P. Maro, John A. Crump

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002589

NLRP3 Inflammasome Activation by Paracoccidioides brasiliensis

Aldo Henrique Tavares, Kelly Grace Magalhães, Raquel Das Neves Almeida, Rafael Correa, Pedro Henrique Burgel, Anamélia Lorenzetti Bocca

PLOS Neglected Tropical Diseases: published December 5, 2013 | https://doi.org/10.1371/journal.pntd.0002595