A frontal view of a single hemisphere of the developing Aedes aegypti fourth instar larval brain is shown. The antennal sensory neurons (red), which have been filled with the dextran dye D7162, innervate the antennal lobe (area circled by yellow dots). The antennal lobe is labeled with mAb nc82 staining (blue), a marker for the synaptic neuropil. Development of these structures was disrupted through chitosan/siRNA nanoparticle targeting of semaphorin-1a. See Mysore et al.
Image Credit: Keshava Mysore
Editorial
Is Sickle Cell Anemia a Neglected Tropical Disease?
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002120
Viewpoints
Strongyloides stercoralis: A Plea for Action
PLOS Neglected Tropical Diseases: published May 9, 2013 | https://doi.org/10.1371/journal.pntd.0002214
From Innovation to Application
Potential Non-invasive Urine-Based Antigen (Protein) Detection Assay to Diagnose Active Visceral Leishmaniasis
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002161
Reviews
Contributions of the Guinea Worm Disease Eradication Campaign toward Achievement of the Millennium Development Goals
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002160
A Public Health Response against Strongyloides stercoralis: Time to Look at Soil-Transmitted Helminthiasis in Full
PLOS Neglected Tropical Diseases: published May 9, 2013 | https://doi.org/10.1371/journal.pntd.0002165
Research Articles
Emergence of Clinically Relevant Non-Tuberculous Mycobacterial Infections in Saudi Arabia
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002234
Cooler Temperatures Destabilize RNA Interference and Increase Susceptibility of Disease Vector Mosquitoes to Viral Infection
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002239
Genetic and Phenotypic Characterization of Manufacturing Seeds for a Tetravalent Dengue Vaccine (DENVax)
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002243
Evolutionary Dynamics of West Nile Virus in the United States, 1999–2011: Phylogeny, Selection Pressure and Evolutionary Time-Scale Analysis
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002245
Prevalence and Diversity of Bartonella Species in Commensal Rodents and Ectoparasites from Nigeria, West Africa
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002246
Association between Response to Albendazole Treatment and β-Tubulin Genotype Frequencies in Soil-transmitted Helminths
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002247
Antibody Signature of Spontaneous Clearance of Chlamydia trachomatis Ocular Infection and Partial Resistance against Re-challenge in a Nonhuman Primate Trachoma Model
PLOS Neglected Tropical Diseases: published May 30, 2013 | https://doi.org/10.1371/journal.pntd.0002248
Microproteinuria during Opisthorchis viverrini Infection: A Biomarker for Advanced Renal and Hepatobiliary Pathologies from Chronic Opisthorchiasis
PLOS Neglected Tropical Diseases: published May 23, 2013 | https://doi.org/10.1371/journal.pntd.0002228
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PLOS Neglected Tropical Diseases: published May 16, 2013 | https://doi.org/10.1371/journal.pntd.0002189
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PLOS Neglected Tropical Diseases: published May 16, 2013 | https://doi.org/10.1371/journal.pntd.0002210
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Disruption of Aedes aegypti Olfactory System Development through Chitosan/siRNA Nanoparticle Targeting of semaphorin-1a
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