Nigeria: “Ground Zero" for the High Prevalence Neglected Tropical Diseases

Peter J. Hotez, Oluwatoyin A. Asojo, Adekunle M. Adesina

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001600

Is Human Immunodeficiency Virus Infection a Risk Factor for Strongyloides stercoralis Hyperinfection and Dissemination

Marc O. Siegel, Gary L. Simon

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001581

Integration of Deworming into HIV Care and Treatment: A Neglected Opportunity

Helen L. Gerns, Laura R. Sangaré, Judd L. Walson

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001738

Alkhurma Viral Hemorrhagic Fever Virus: Proposed Guidelines for Detection, Prevention, and Control in Saudi Arabia

Ziad A. Memish, Shamsudeen F. Fagbo, Abdullah M. Assiri, Pierre Rollin, Ali M. Zaki, Remi Charrel, Chris Mores, Adam MacNeil

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001604

A Diagnostics Platform for the Integrated Mapping, Monitoring, and Surveillance of Neglected Tropical Diseases: Rationale and Target Product Profiles

Anthony W. Solomon, Dirk Engels, Robin L. Bailey, Isobel M. Blake, Simon Brooker, Jia-Xu Chen, Jun-Hu Chen, Thomas S. Churcher, Chris J. Drakeley, Tansy Edwards, Alan Fenwick, Michael French, Albis Francesco Gabrielli, Nicholas C. Grassly, Emma M. Harding-Esch, Martin J. Holland, Artemis Koukounari, Patrick J. Lammie, Jacqueline Leslie, David C. Mabey, Mohamed Rhajaoui, W. Evan Secor, J. Russell Stothard, Hu Wei, A. Lee Willingham, Xiao-Nong Zhou, Rosanna W. Peeling

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001746

Spontaneous Clearance of a Secondary Buruli Ulcer Lesion Emerging Ten Months after Completion of Chemotherapy—A Case Report from Togo

Marcus Beissner, Ebekalisai Piten, Issaka Maman, Dominik Symank, Moritz Jansson, Jörg Nitschke, Komi Amekuse, Basil Kobara, Franz Wiedemann, Harald Hoffmann, Adolf Diefenhardt, Kossi Badziklou, Abiba Banla Kere, Thomas Löscher, Gisela Bretzel

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001747

Activation of Indoleamine 2,3-Dioxygenase in Patients with Scrub Typhus and Its Role in Growth Restriction of Orientia tsutsugamushi

Thanavadee Prachason, Kanittha Konhan, Piyapat Pongnarin, Somruedee Chatsiricharoenkul, Yupin Suputtamongkol, Chanin Limwongse

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001731

Dengue Infection in Children in Ratchaburi, Thailand: A Cohort Study. I. Epidemiology of Symptomatic Acute Dengue Infection in Children, 2006–2009

Arunee Sabchareon, Chukiat Sirivichayakul, Kriengsak Limkittikul, Pornthep Chanthavanich, Saravudh Suvannadabba, Vithaya Jiwariyavej, Wut Dulyachai, Krisana Pengsaa, Harold S. Margolis, G. William Letson

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001732

Diverse Inhibitor Chemotypes Targeting Trypanosoma cruzi CYP51

Shamila S. Gunatilleke, Claudia M. Calvet, Jonathan B. Johnston, Chiung-Kuang Chen, Grigori Erenburg, Jiri Gut, Juan C. Engel, Kenny K. H. Ang, Joseph Mulvaney, Steven Chen, Michelle R. Arkin, James H. McKerrow, Larissa M. Podust

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001736

Detection of Antibiotic Resistance in Leprosy Using GenoType LepraeDR, a Novel Ready-To-Use Molecular Test

Emmanuelle Cambau, Aurélie Chauffour-Nevejans, Liana Tejmar-Kolar, Masanori Matsuoka, Vincent Jarlier

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001739

Identification and Characterization of Argonaute Protein, Ago2 and Its Associated Small RNAs in Schistosoma japonicum

Pengfei Cai, Xianyu Piao, Nan Hou, Shuai Liu, Heng Wang, Qijun Chen

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001745

Evaluation of Circulating Cathodic Antigen (CCA) Urine-Tests for Diagnosis of Schistosoma mansoni Infection in Cameroon

Louis-Albert Tchuem Tchuenté, Césaire Joris Kueté Fouodo, Romuald Isaka Kamwa Ngassam, Laurentine Sumo, Calvine Dongmo Noumedem, Christian Mérimé Kenfack, Nestor Feussom Gipwe, Esther Dankoni Nana, J. Russell Stothard, David Rollinson

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001758

Research on Motor Neuron Diseases Konzo and Neurolathyrism: Trends from 1990 to 2010

Delphin Diasolua Ngudi, Yu-Haey Kuo, Marc Van Montagu, Fernand Lambein

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001759

Regulatory T Cells Enhance Susceptibility to Experimental Trypanosoma Congolense Infection Independent of Mouse Genetic Background

Ifeoma Okwor, Chukwunonso Onyilagha, Shiby Kuriakose, Zhirong Mou, Ping Jia, Jude E. Uzonna

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001761

Whole Organism High-Content Screening by Label-Free, Image-Based Bayesian Classification for Parasitic Diseases

Ross A. Paveley, Nuha R. Mansour, Irene Hallyburton, Leo S. Bleicher, Alex E. Benn, Ivana Mikic, Alessandra Guidi, Ian H. Gilbert, Andrew L. Hopkins, Quentin D. Bickle

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001762

Seroprevalence of Chagas Infection in the Donor Population

Ben A. Zaniello, Deborah A. Kessler, Katherine M. Vine, Kathleen M. Grima, Scott A. Weisenberg

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001771

Significantly Reduced Intensity of Infection but Persistent Prevalence of Schistosomiasis in a Highly Endemic Region in Mali after Repeated Treatment

Aly Landouré, Robert Dembélé, Seydou Goita, Mamadou Kané, Marjon Tuinsma, Moussa Sacko, Emily Toubali, Michael D. French, Adama D. Keita, Alan Fenwick, Mamadou S. Traoré, Yaobi Zhang

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001774

A Simple Strain Typing Assay for Trypanosoma cruzi: Discrimination of Major Evolutionary Lineages from a Single Amplification Product

Raul O. Cosentino, Fernán Agüero

PLOS Neglected Tropical Diseases: published July 31, 2012 | https://doi.org/10.1371/journal.pntd.0001777

Partnering Parasites: Evidence of Synergism between Heavy Schistosoma haematobium and Plasmodium Species Infections in Kenyan Children

Lia S. Florey, Charles H. King, Melissa K. Van Dyke, Eric M. Muchiri, Peter L. Mungai, Peter A. Zimmerman, Mark L. Wilson

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001723

Efficacy of Praziquantel against Schistosoma mekongi and Opisthorchis viverrini: A Randomized, Single-Blinded Dose-Comparison Trial

Leonore Lovis, Tippi K. Mak, Khampheng Phongluxa, Phonepasong Ayé Soukhathammavong, Youthanavanh Vonghachack, Jennifer Keiser, Penelope Vounatsou, Marcel Tanner, Christoph Hatz, Jürg Utzinger, Peter Odermatt, Kongsap Akkhavong

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001726

In-silico Investigation of Antitrypanosomal Phytochemicals from Nigerian Medicinal Plants

William N. Setzer, Ifedayo V. Ogungbe

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001727

Ascorbic Acid Has Superior Ex Vivo Antiproliferative, Cell Death-Inducing and Immunomodulatory Effects over IFN-α in HTLV-1-Associated Myelopathy

Britta Moens, Daniele Decanine, Soraya Maria Menezes, Ricardo Khouri, Gilvanéia Silva-Santos, Giovanni Lopez, Carolina Alvarez, Michael Talledo, Eduardo Gotuzzo, Ramon de Almeida Kruschewsky, Bernardo Galvão-Castro, Anne-Mieke Vandamme, Johan Van Weyenbergh

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001729

Pharmacology of DB844, an Orally Active aza Analogue of Pafuramidine, in a Monkey Model of Second Stage Human African Trypanosomiasis

John K. Thuita, Michael Z. Wang, John M. Kagira, Cathrine L. Denton, Mary F. Paine, Raymond E. Mdachi, Grace A. Murilla, Shelley Ching, David W. Boykin, Richard R. Tidwell, James E. Hall, Reto Brun

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001734

Adenovirus Delivered Short Hairpin RNA Targeting a Conserved Site in the 5′ Non-Translated Region Inhibits All Four Serotypes of Dengue Viruses

Anil Babu Korrapati, Gokul Swaminathan, Aarti Singh, Navin Khanna, Sathyamangalam Swaminathan

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001735

Leishmania major Infection in Humanized Mice Induces Systemic Infection and Provokes a Nonprotective Human Immune Response

Anja Kathrin Wege, Christian Florian, Wolfgang Ernst, Nicole Zimara, Ulrike Schleicher, Frank Hanses, Maximilian Schmid, Uwe Ritter

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001741

Safety of the Recombinant Cholera Toxin B Subunit, Killed Whole-Cell (rBS-WC) Oral Cholera Vaccine in Pregnancy

Ramadhan Hashim, Ahmed M. Khatib, Godwin Enwere, Jin Kyung Park, Rita Reyburn, Mohammad Ali, Na Yoon Chang, Deok Ryun Kim, Benedikt Ley, Kamala Thriemer, Anna Lena Lopez, John D. Clemens, Jacqueline L. Deen, Sunheang Shin, Christian Schaetti, Raymond Hutubessy, Maria Teresa Aguado, Marie Paule Kieny, David Sack, Stephen Obaro, Attiye J. Shaame, Said M. Ali, Abdul A. Saleh, Lorenz von Seidlein, Mohamed S. Jiddawi

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001743

Maternal Geohelminth Infections Are Associated with an Increased Susceptibility to Geohelminth Infection in Children: A Case-Control Study

Raaj S. Mehta, Alejandro Rodriguez, Martha Chico, Irene Guadalupe, Nely Broncano, Carlos Sandoval, Fernanda Tupiza, Edward Mitre, Philip J. Cooper

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001753

Wolbachia Induces Density-Dependent Inhibition to Dengue Virus in Mosquito Cells

Peng Lu, Guowu Bian, Xiaoling Pan, Zhiyong Xi

PLOS Neglected Tropical Diseases: published July 24, 2012 | https://doi.org/10.1371/journal.pntd.0001754

Complement Inhibitors from Scabies Mites Promote Streptococcal Growth – A Novel Mechanism in Infected Epidermis?

Angela Mika, Simone L. Reynolds, Darren Pickering, David McMillan, Kadaba S. Sriprakash, David J. Kemp, Katja Fischer

PLOS Neglected Tropical Diseases: published July 17, 2012 | https://doi.org/10.1371/journal.pntd.0001563

Effective Control of Schistosoma haematobium Infection in a Ghanaian Community following Installation of a Water Recreation Area

Karen C. Kosinski, Michael N. Adjei, Kwabena M. Bosompem, Jonathan J. Crocker, John L. Durant, Dickson Osabutey, Jeanine D. Plummer, Miguel J. Stadecker, Anjuli D. Wagner, Mark Woodin, David M. Gute

PLOS Neglected Tropical Diseases: published July 17, 2012 | https://doi.org/10.1371/journal.pntd.0001709

Immune Evasion and Recognition of the Syphilis Spirochete in Blood and Skin of Secondary Syphilis Patients: Two Immunologically Distinct Compartments

Adriana R. Cruz, Lady G. Ramirez, Ana V. Zuluaga, Allan Pillay, Christine Abreu, Carlos A. Valencia, Carson La Vake, Jorge L. Cervantes, Star Dunham-Ems, Richard Cartun, Domenico Mavilio, Justin D. Radolf, Juan C. Salazar

PLOS Neglected Tropical Diseases: published July 17, 2012 | https://doi.org/10.1371/journal.pntd.0001717

Fine Scale Spatiotemporal Clustering of Dengue Virus Transmission in Children and Aedes aegypti in Rural Thai Villages

In-Kyu Yoon, Arthur Getis, Jared Aldstadt, Alan L. Rothman, Darunee Tannitisupawong, Constantianus J. M. Koenraadt, Thanyalak Fansiri, James W. Jones, Amy C. Morrison, Richard G. Jarman, Ananda Nisalak, Mammen P. Mammen Jr., Suwich Thammapalo, Anon Srikiatkhachorn, Sharone Green, Daniel H. Libraty, Robert V. Gibbons, Timothy Endy, Chusak Pimgate, Thomas W. Scott

PLOS Neglected Tropical Diseases: published July 17, 2012 | https://doi.org/10.1371/journal.pntd.0001730

Seroprevalence and Risk Factors for Taenia solium Cysticercosis in Rural Pigs of Northern Peru

César M. Jayashi, Gianfranco Arroyo, Marshall W. Lightowlers, Héctor H. García, Silvia Rodríguez, Armando E. Gonzalez

PLOS Neglected Tropical Diseases: published July 17, 2012 | https://doi.org/10.1371/journal.pntd.0001733

TNF-α Involvement in Insulin Resistance Induced by Experimental Scorpion Envenomation

Aouatef Ait-Lounis, Fatima Laraba-Djebari

PLOS Neglected Tropical Diseases: published July 17, 2012 | https://doi.org/10.1371/journal.pntd.0001740

Primary Vaccination with Low Dose Live Dengue 1 Virus Generates a Proinflammatory, Multifunctional T Cell Response in Humans

Janet C. Lindow, Nathan Borochoff-Porte, Anna P. Durbin, Stephen S. Whitehead, Kelly A. Fimlaid, Janice Y. Bunn, Beth D. Kirkpatrick

PLOS Neglected Tropical Diseases: published July 17, 2012 | https://doi.org/10.1371/journal.pntd.0001742

Podoconiosis in East and West Gojam Zones, Northern Ethiopia

Yordanos B. Molla, Sara Tomczyk, Tsige Amberbir, Abreham Tamiru, Gail Davey

PLOS Neglected Tropical Diseases: published July 17, 2012 | https://doi.org/10.1371/journal.pntd.0001744

Relationship between Immediate Post-Operative Appearance and 6-Week Operative Outcome in Trichiasis Surgery

Shannath L. Merbs, Jennifer C. Harding, Sandra D. Cassard, Beatriz E. Munoz, Sheila K. West, Emily W. Gower

PLOS Neglected Tropical Diseases: published July 10, 2012 | https://doi.org/10.1371/journal.pntd.0001718

Kinetics of Antibody Response in BALB/c and C57BL/6 Mice Bitten by Phlebotomus papatasi

Michaela Vlkova, Iva Rohousova, Jitka Hostomska, Lucia Pohankova, Lenka Zidkova, Jan Drahota, Jesus G. Valenzuela, Petr Volf

PLOS Neglected Tropical Diseases: published July 10, 2012 | https://doi.org/10.1371/journal.pntd.0001719

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Geneviève M. C. Labbé, Sarah Scaife, Siân A. Morgan, Zoë H. Curtis, Luke Alphey

PLOS Neglected Tropical Diseases: published July 10, 2012 | https://doi.org/10.1371/journal.pntd.0001724

Trypanosoma brucei gambiense Group 1 Is Distinguished by a Unique Amino Acid Substitution in the HpHb Receptor Implicated in Human Serum Resistance

Rebecca E. Symula, Jon S. Beadell, Mark Sistrom, Kehinde Agbebakun, Oliver Balmer, Wendy Gibson, Serap Aksoy, Adalgisa Caccone

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Methodology for Definition of Yellow Fever Priority Areas, Based on Environmental Variables and Multiple Correspondence Analyses

Eduardo Stramandinoli Moreno, Rita de Cássia Barradas Barata

PLOS Neglected Tropical Diseases: published July 3, 2012 | https://doi.org/10.1371/journal.pntd.0001658

Cure of Hookworm Infection with a Cysteine Protease Inhibitor

Jon J. Vermeire, Lorine D. Lantz, Conor R. Caffrey

PLOS Neglected Tropical Diseases: published July 3, 2012 | https://doi.org/10.1371/journal.pntd.0001680

Sensitive and Specific Detection of Trypanosoma cruzi DNA in Clinical Specimens Using a Multi-Target Real-Time PCR Approach

Yvonne Qvarnstrom, Alejandro G. Schijman, Vincent Veron, Christine Aznar, Francis Steurer, Alexandre J. da Silva

PLOS Neglected Tropical Diseases: published July 3, 2012 | https://doi.org/10.1371/journal.pntd.0001689

Safety and Immunogenicity of rSh28GST Antigen in Humans: Phase 1 Randomized Clinical Study of a Vaccine Candidate against Urinary Schistosomiasis

Gilles Riveau, Dominique Deplanque, Franck Remoué, Anne-Marie Schacht, Hubert Vodougnon, Monique Capron, Michel Thiry, Joseph Martial, Christian Libersa, André Capron

PLOS Neglected Tropical Diseases: published July 3, 2012 | https://doi.org/10.1371/journal.pntd.0001704

Improved Serodiagnosis of Cystic Echinococcosis Using the New Recombinant 2B2t Antigen

Ana Hernández-González, Saúl Santivañez, Héctor H. García, Silvia Rodríguez, Santiago Muñoz, Guillermo Ramos, Antonio Orduña, Mar Siles-Lucas

PLOS Neglected Tropical Diseases: published July 3, 2012 | https://doi.org/10.1371/journal.pntd.0001714

Dendritic Cell-Mediated Vaccination Relies on Interleukin-4 Receptor Signaling to Avoid Tissue Damage after Leishmania major Infection of BALB/c Mice

Anita Masic, Ramona Hurdayal, Natalie E. Nieuwenhuizen, Frank Brombacher, Heidrun Moll

PLOS Neglected Tropical Diseases: published July 3, 2012 | https://doi.org/10.1371/journal.pntd.0001721

Breeding Sites of Phlebotomus sergenti, the Sand Fly Vector of Cutaneous Leishmaniasis in the Judean Desert

Aviad Moncaz, Roy Faiman, Oscar Kirstein, Alon Warburg

PLOS Neglected Tropical Diseases: published July 3, 2012 | https://doi.org/10.1371/journal.pntd.0001725