March 2009

This photograph shows typical African village pigs. Such pigs are mainly free roaming or semi-confined and their close contact with humans is one of the major risk factors for the transmission of Taenia solium taeniasis and cysticercosis. Human cysticercosis can cause serious neurological disorders such as acquired epilepsy. Although T. solium cysticercosis is being eradicated in most industrialized countries, with their intensified pig husbandry systems, it remains an important but neglected zoonotic disease in low-income countries (see Praet et al., doi:10.1371/journal.pntd.0000406).

Image Credit: Nicolas Praet, Institute of Tropical Medicine of Antwerp

Editorial

Toxocariasis: America's Most Common Neglected Infection of Poverty and a Helminthiasis of Global Importance?

Peter J. Hotez, Patricia P. Wilkins

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000400

Viewpoints

Challenges in Retaining Research Scientists beyond the Doctoral Level in Kenya

Lynette Isabella Ochola, Evelyn Gitau

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000345

Expert Commentary

Mass Antibiotic Treatment Alone Does Not Eliminate Ocular Chlamydial Infection

Paul M. Emerson, Jeremiah Ngondi

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000394

Historical Profiles and Perspectives

From Tucson to Genomics and Transgenics: The Vector Biology Network and the Emergence of Modern Vector Biology

Barry J. Beaty, Denis J. Prager, Anthony A. James, Marcelo Jacobs-Lorena, Louis H. Miller, John H. Law, Frank H. Collins, Fotis C. Kafatos

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000343

From Innovation to Application

A Global Public Database of Disease Vector and Reservoir Distributions

Alexander Moffett, Stavana Strutz, Nelson Guda, Camila González, Maria Cristina Ferro, Víctor Sánchez-Cordero, Sahotra Sarkar

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000378

Research Articles

Estimating Household and Community Transmission of Ocular Chlamydia trachomatis

Isobel M. Blake, Matthew J. Burton, Robin L. Bailey, Anthony W. Solomon, Sheila West, Beatriz Muñoz, Martin J. Holland, David C. W. Mabey, Manoj Gambhir, María-Gloria Basáñez, Nicholas C. Grassly

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000401

The Costs and Cost-Effectiveness of Mass Treatment for Intestinal Nematode Worm Infections Using Different Treatment Thresholds

Andrew Hall, Sue Horton, Nilanthi de Silva

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000402

Immunologic Responses to Vibrio cholerae in Patients Co-Infected with Intestinal Parasites in Bangladesh

Jason B. Harris, Michael J. Podolsky, Taufiqur R. Bhuiyan, Fahima Chowdhury, Ashraful I. Khan, Regina C. LaRocque, Tanya Logvinenko, Jennifer Kendall, Abu S. G. Faruque, Cathryn R. Nagler, Edward T. Ryan, Firdausi Qadri, Stephen B. Calderwood

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000403

Successful Interruption of Transmission of Onchocerca volvulus in the Escuintla-Guatemala Focus, Guatemala

Rodrigo J. Gonzalez, Nancy Cruz-Ortiz, Nidia Rizzo, Jane Richards, Guillermo Zea-Flores, Alfredo Domínguez, Mauricio Sauerbrey, Eduardo Catú, Orlando Oliva, Frank O. Richards Jr, Kim A. Lindblade

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000404

The Disease Burden of Taenia solium Cysticercosis in Cameroon

Nicolas Praet, Niko Speybroeck, Rafael Manzanedo, Dirk Berkvens, Denis Nsame Nforninwe, André Zoli, Fabrice Quet, Pierre-Marie Preux, Hélène Carabin, Stanny Geerts

PLOS Neglected Tropical Diseases: published March 31, 2009 | https://doi.org/10.1371/journal.pntd.0000406

Assays to Detect β-Tubulin Codon 200 Polymorphism in Trichuris trichiura and Ascaris lumbricoides

Aissatou Diawara, Lesley J. Drake, Richard R. Suswillo, Jimmy Kihara, Donald A. P. Bundy, Marilyn E. Scott, Carli Halpenny, J. Russell Stothard, Roger K. Prichard

PLOS Neglected Tropical Diseases: published March 24, 2009 | https://doi.org/10.1371/journal.pntd.0000397

Cathepsin F Cysteine Protease of the Human Liver Fluke, Opisthorchis viverrini

Porntip Pinlaor, Natthawut Kaewpitoon, Thewarach Laha, Banchob Sripa, Sasithorn Kaewkes, Maria E. Morales, Victoria H. Mann, Sandi K. Parriott, Sutas Suttiprapa, Mark W. Robinson, Joyce To, John P. Dalton, Alex Loukas, Paul J. Brindley

PLOS Neglected Tropical Diseases: published March 24, 2009 | https://doi.org/10.1371/journal.pntd.0000398

Necator americanus Infection: A Possible Cause of Altered Dendritic Cell Differentiation and Eosinophil Profile in Chronically Infected Individuals

Ricardo T. Fujiwara, Guilherme G. L. Cançado, Paula A. Freitas, Helton C. Santiago, Cristiano Lara Massara, Omar dos Santos Carvalho, Rodrigo Corrêa-Oliveira, Stefan M. Geiger, Jeffrey Bethony

PLOS Neglected Tropical Diseases: published March 24, 2009 | https://doi.org/10.1371/journal.pntd.0000399

The Population Structure of Glossina palpalis gambiensis from Island and Continental Locations in Coastal Guinea

Philippe Solano, Sophie Ravel, Jeremy Bouyer, Mamadou Camara, Moise S. Kagbadouno, Naomi Dyer, Laetitia Gardes, Damien Herault, Martin J. Donnelly, Thierry De Meeûs

PLOS Neglected Tropical Diseases: published March 17, 2009 | https://doi.org/10.1371/journal.pntd.0000392

A Rationale for Schistosomiasis Control in Elementary Schools of the Rainforest Zone of Pernambuco, Brazil

Tereza C. Favre, Ana P. B. Pereira, Aline F. Galvão, Luciana C. Zani, Constança S. Barbosa, Otávio S. Pieri

PLOS Neglected Tropical Diseases: published March 17, 2009 | https://doi.org/10.1371/journal.pntd.0000395

What Will Happen If We Do Nothing To Control Trachoma: Health Expectancies for Blinding Trachoma in Southern Sudan

Jeremiah M. Ngondi, Fiona E. Matthews, Mark H. Reacher, Jonathan King, Carol Brayne, Hebe Gouda, Paul M. Emerson

PLOS Neglected Tropical Diseases: published March 17, 2009 | https://doi.org/10.1371/journal.pntd.0000396

Post-Epidemic Chikungunya Disease on Reunion Island: Course of Rheumatic Manifestations and Associated Factors over a 15-Month Period

Daouda Sissoko, Denis Malvy, Khaled Ezzedine, Philippe Renault, Frederic Moscetti, Martine Ledrans, Vincent Pierre

PLOS Neglected Tropical Diseases: published March 10, 2009 | https://doi.org/10.1371/journal.pntd.0000389

Cover

African village pigs.