July 2008

Advanced analytical techniques have permitted the identification of new nematode proteins from a wide survey of genes expressed in human, animal, and plant parasites. These may include novel drug and vaccine targets (see Wasmuth et al. doi:10.1371/journal.pntd.0000258).

Image Credit: Micrograph by Leo Liu, final image by James Wasmuth and Mark Blaxter.

Editorial

Tropical Anemia: One of Africa's Great Killers and a Rationale for Linking Malaria and Neglected Tropical Disease Control to Achieve a Common Goal

Peter J. Hotez, David H. Molyneux

PLOS Neglected Tropical Diseases: published July 30, 2008 | https://doi.org/10.1371/journal.pntd.0000270

Interview

Engaging the Community: An Interview with Uche Amazigo

Hannah Brown

PLOS Neglected Tropical Diseases: published July 30, 2008 | https://doi.org/10.1371/journal.pntd.0000268

Expert Commentary

Tracking the Odysseys of Juvenile Schistosomes to Understand Host Interactions

Malcolm K. Jones, Sara Lustigman, Alex Loukas

PLOS Neglected Tropical Diseases: published July 16, 2008 | https://doi.org/10.1371/journal.pntd.0000257

Review

The NIH-NIAID Schistosomiasis Resource Center

Fred A. Lewis, Yung-san Liang, Nithya Raghavan, Matty Knight

PLOS Neglected Tropical Diseases: published July 30, 2008 | https://doi.org/10.1371/journal.pntd.0000267

Research Articles

Metabolic Profiling of an Echinostoma caproni Infection in the Mouse for Biomarker Discovery

Jasmina Saric, Jia V. Li, Yulan Wang, Jennifer Keiser, Jake G. Bundy, Elaine Holmes, Jürg Utzinger

PLOS Neglected Tropical Diseases: published July 2, 2008 | https://doi.org/10.1371/journal.pntd.0000254

On the Extent and Origins of Genic Novelty in the Phylum Nematoda

James Wasmuth, Ralf Schmid, Ann Hedley, Mark Blaxter

PLOS Neglected Tropical Diseases: published July 2, 2008 | https://doi.org/10.1371/journal.pntd.0000258

Development of Functional Genomic Tools in Trematodes: RNA Interference and Luciferase Reporter Gene Activity in Fasciola hepatica

Gabriel Rinaldi, Maria E. Morales, Martín Cancela, Estela Castillo, Paul J. Brindley, José F. Tort

PLOS Neglected Tropical Diseases: published July 9, 2008 | https://doi.org/10.1371/journal.pntd.0000260

Differentiation and Gene Flow among European Populations of Leishmania infantum MON-1

Katrin Kuhls, Carmen Chicharro, Carmen Cañavate, Sofia Cortes, Lenea Campino, Christos Haralambous, Ketty Soteriadou, Francine Pratlong, Jean-Pierre Dedet, Isabel Mauricio, Michael Miles, Matthias Schaar, Sebastian Ochsenreither, Oliver A. Radtke, Gabriele Schönian

PLOS Neglected Tropical Diseases: published July 9, 2008 | https://doi.org/10.1371/journal.pntd.0000261

Acute Schistosoma mansoni Infection Increases Susceptibility to Systemic SHIV Clade C Infection in Rhesus Macaques after Mucosal Virus Exposure

Agnès-Laurence Chenine, Ela Shai-Kobiler, Lisa N. Steele, Helena Ong, Peter Augostini, Ruijiang Song, Sandra J. Lee, Patrick Autissier, Ruth M. Ruprecht, W. Evan Secor

PLOS Neglected Tropical Diseases: published July 23, 2008 | https://doi.org/10.1371/journal.pntd.0000265

The Interplay between Entamoeba and Enteropathogenic Bacteria Modulates Epithelial Cell Damage

José Manuel Galván-Moroyoqui, M. del Carmen Domínguez-Robles, Elizabeth Franco, Isaura Meza

PLOS Neglected Tropical Diseases: published July 23, 2008 | https://doi.org/10.1371/journal.pntd.0000266

Landscape Diversity Related to Buruli Ulcer Disease in Côte d'Ivoire

Télesphore Brou, Hélène Broutin, Eric Elguero, Henri Asse, Jean-François Guegan

PLOS Neglected Tropical Diseases: published July 30, 2008 | https://doi.org/10.1371/journal.pntd.0000271

Cover

Nematode Protein Diversity Surveyed