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Schistosomes require aquatic snails as an intermediate host. In this work from Blouin et al, results from genome-wide mapping of the Biomphalaria glabrata host genome add to a growing body of work that suggests TM1 genes may play an important role in snail-schistosome compatibility polymorphisms. Identifying the interacting molecules on the schistosome side, and how they interact with snail proteins, might reveal ways we could genetically modify snails to make them unable to transmit schistosomes to humans.
Image Credit: Blouin et al, 2024
Citation: (2024) PLoS Neglected Tropical Diseases Issue Image | Vol. 18(9) October 2024. PLoS Negl Trop Dis 18(9): ev18.i09. https://doi.org/10.1371/image.pntd.v18.i09
Published: October 6, 2024
Copyright: © 2024 . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Schistosomes require aquatic snails as an intermediate host. In this work from Blouin et al, results from genome-wide mapping of the Biomphalaria glabrata host genome add to a growing body of work that suggests TM1 genes may play an important role in snail-schistosome compatibility polymorphisms. Identifying the interacting molecules on the schistosome side, and how they interact with snail proteins, might reveal ways we could genetically modify snails to make them unable to transmit schistosomes to humans.
Image Credit: Blouin et al, 2024