Figures
Leishmania chagasi-Infected Human Monocyte-Derived Macrophages Co-Cultured with Autologous Leishmania-Naïve T Cells
Human monocyte-derived macrophages from a Leishmania-naïve donor were infected with Leishmania chagasi promastigote for 24 hrs, and co-cultured with purified CD3+ autologous T cells for an additional 24 hours. Cells were fixed and stained with Diff Quik. Images (600x) show an uninfected macrophage and several infected macrophages with intracellular amastigotes. Numerous T cells are visible in the image (see Ettinger and Wilson, doi:10.1371/journal.pntd.0000252).
Image Credit: Image generated by Nicholas A. Ettinger.
Citation: (2008) PLoS Neglected Tropical Diseases Issue Image | Vol. 2(6) June 2008. PLoS Neglect Trop Dis 2(6): ev02.i06. https://doi.org/10.1371/image.pntd.v02.i06
Published: June 25, 2008
Copyright: © 2008 Nicholas A. Ettinger. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Human monocyte-derived macrophages from a Leishmania-naïve donor were infected with Leishmania chagasi promastigote for 24 hrs, and co-cultured with purified CD3+ autologous T cells for an additional 24 hours. Cells were fixed and stained with Diff Quik. Images (600x) show an uninfected macrophage and several infected macrophages with intracellular amastigotes. Numerous T cells are visible in the image (see Ettinger and Wilson, doi:10.1371/journal.pntd.0000252).
Image Credit: Image generated by Nicholas A. Ettinger.