Figures
Mouse Left Ear
Shown is cutaneous lesion development in a BALB/c mouse after inoculation of Leishmania braziliensis into the ear dermis. Previous research in mice has shown that immunity to sandfly saliva protects against the development of leishmaniasis. Researchers in Brazil observed that mice injected with sandfly saliva develop a specific response against salivary proteins; however, mice challenged with live Leishmania braziliensis in the presence of the saliva were not protected. Their findings could indicate possible hurdles in the development of leishmaniasis vaccines based on sandfly saliva (see de Moura et al., e84).
Image Credit: © 2007 Fabiano Oliveira
Citation: (2007) PLoS Neglected Tropical Diseases Issue Image | Vol. 1(2) November 2007. PLoS Negl Trop Dis 1(2): https://doi.org/10.1371/image.pntd.v01.i02
Published: November 28, 2007
Copyright: © 2007 Public Library of Science. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Shown is cutaneous lesion development in a BALB/c mouse after inoculation of Leishmania braziliensis into the ear dermis. Previous research in mice has shown that immunity to sandfly saliva protects against the development of leishmaniasis. Researchers in Brazil observed that mice injected with sandfly saliva develop a specific response against salivary proteins; however, mice challenged with live Leishmania braziliensis in the presence of the saliva were not protected. Their findings could indicate possible hurdles in the development of leishmaniasis vaccines based on sandfly saliva (see de Moura et al., e84).
Image Credit: © 2007 Fabiano Oliveira