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Fig 1.

Normal and abnormal lymph node features.

A) An example of a plague bubo without abnormal radiological findings. While enlarged, this lymph node exhibits relatively normal features including a well-defined, oval-shaped capsule with a distinct echogenic hilum and normal surrounding perinodal tissue. B) Anomalous findings on ultrasound indicative radiological progression would include blurring to the edges of the capsule (which may be indicative of oedema), a circular-shaped capsule, a decrease in the size of the hilum or a total absence of the hilum.

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Table 1.

Demographic characteristics.

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Fig 2.

Clinical characteristics of plague buboes at D1 and D11.

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Fig 3.

Sonographic characteristics of plague buboes at D1 and D11.

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Fig 4.

Scatterplot of bubo sizes per participant on D1, D4 and D11.

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Fig 5.

Ultrasound images taken on Day 1, Day 4 and Day 11 for case report #1.

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Fig 6.

Ultrasound images taken on Day 1, Day 4 and Day 11 for case report #2.

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Table 2.

Median (IQR) absolute and percentage difference between digital calliper and ultrasound measurements.

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Table 3.

Median (IQR) absolute and percentage difference between radiologists and study sonographers.

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Fig 7.

Agreement between experts and non-experts by characteristic and zone.

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Fig 8.

Agreement between experts and non-experts by characteristic and study day.

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