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Fig 1.

Flow chart outlining the search and review process, the records identified, included, and excluded as well as the reasons for exclusion.

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Fig 2.

Publication year and geographic distribution of included studies (n = 60).

Bubble position shows year and WHO region; bubble color indicates disease (low-frequency (total = 1) diseases combined as “Others”); bubble size indicates number of studies (1 or 2).

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Table 1.

Summary of burden metrics used in disease burden estimation, stratified by disease type and region.

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Table 2.

Summary of covariates used in disease burden estimation.

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Table 2 Expand

Table 3.

Key recommendations for advancing acute tropical infectious disease burden estimation.

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Table 3 Expand