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Fig 1.

Selection of baseline study cohort.

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Table 1.

Baseline demographic characteristics of the cohort of participants followed-up.

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Table 2.

Seroconversion/-reversion prevalence in participants followed up.

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Table 3.

First follow-up–time and additional IVM intake effects on FTS-CFA.

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Table 4.

Second follow-up–time and additional IVM intake effects on FTS-CFA.

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Table 5.

First follow-up–time and additional IVM intake effects on Og4C3 CFA.

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Fig 2.

Changes in FTS-CFA status during first and second follow-ups between a period of 8–13 months (McNemar test). One participant who was CFA-negative from baseline became positive at first follow-up but became negative again at the second follow-up.

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Fig 3.

Changes in the Og4C3 antigen levels in baseline FTS-CFA positive participants followed-up (A) individuals positive at both baseline and first follow-up (n = 49) (B) participants positive at baseline but either positive or negative at first follow-up (n = 120).

Antigen unit axis expressed in log10 scale. Wilcoxon signed rank test.

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Fig 4.

Og4C3 CFA baseline status changes during first follow-up.

McNemar-Bowker test.

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Fig 5.

Changes in Og4C3 antigen levels for (A) individuals positive at both baseline and first follow-up (n = 29) (B) participants positive at baseline but either positive or negative at first follow-up (n = 44).

Antigen unit axis expressed in log10 scale. Wilcoxon signed rank test.

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Fig 5 Expand

Table 6.

Baseline and first follow-up CFA and MF characteristics of previous MF positives.

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Table 6 Expand