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Fig 1.

Study design and participants included in the study.

TSM: Talaromycosis marneffei, IRIS: immune reconstitution inflammatory syndrome.

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Table 1.

Clinical manifestations related to TSM-associated IRIS in IRIS group.

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Fig 2.

Histogram showing the number of patients who developed IRIS over time after ART initiation.

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Fig 3.

Comparisons of laboratory variables at baseline, ART initiation, and IRIS onset in IRIS group.

Significant differences (P < 0.05) between different time points are indicated. ART; antiretroviral therapy; IRIS, immune reconstitution inflammatory syndrome. CRP: C-reactive protein, WBC: white blood cell, MONO: monocytes, HGB: hemoglobin, PLT: platelets, PCT: procalcitonin, ALB: albumin, ALT: alanine aminotransferase, AST: aspartate aminotransferase.

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Table 2.

Baseline demographic and clinical characteristics of IRIS group and non-IRIS group.

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Table 2 Expand

Table 3.

Comparison of laboratory results between IRIS and non-IRIS groups at IRIS onset.

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Table 3 Expand

Fig 4.

The comparison of CD4+ count, CD4/CD8 ratio, and HIV RNA load levels.

(A). CD4+ count at baseline and IRIS onset. (B). Increase in CD4+ count from baseline to IRIS onset. (C). CD4+/CD8+ ratio at baseline and IRIS onset. (D). Increase in CD4+/CD8+ ratio from baseline to IRIS onset. (E). HIV RNA load at baseline and IRIS onset. (F). Decrease in HIV RNA load from baseline to IRIS onset. ART: antiretroviral therapy, IRIS: immune reconstitution inflammatory syndrome.

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Fig 4 Expand

Table 4.

Comparison of the hospitalization duration, readmission rate, and mortality rate between IRIS and non-IRIS groups.

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Table 4 Expand