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Fig 1.

Map of Uganda showing the geographic location of Crimean-Congo hemorrhagic fever cases in relation to Sudan virus disease outbreak, September 2022- January 2023.

This map was created using QGIS, v 3.22.5, a free and open-source geographic information system available at: https://qgis.org/project/overview/. The Uganda map base layers were accessed from Humanitarian Data exchange v.1.83.2 (Uganda administrative boundaries - UGANDA BOUNDARIES SHAPEFILES AS OF 17 08 2018.zip - Humanitarian Data Exchange (humdata.org).

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Fig 2.

Trends of viral hemorrhagic fever suspected samples received and cases of Ebola disease (SUDV) and Crimean-Congo hemorrhagic fever identified between June 2022 to May 2023 at Uganda Virus Research Institute, Entebbe, Uganda.

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Table 1.

Baseline Characteristics of Crimean-Congo Hemorrhagic Fever Cases in Uganda, September 2022 –January 2023 (n = 13).

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Fig 3.

Inferred evolutionary relationships for all available full length CCHFV genomes, including recent and historic CCHFV genomes from Uganda.

Historic (1956–2019) genomes are highlighted green, and recent (March-December 2022) genomes are highlighted blue. The S-segment phylogenetic tree contains two recent Ugandan-specific clades, in addition to a third clade containing two sequences from the 1950s and one from 2022. The M-segment phylogenetic tree includes Ugandan sequences split onto two clades. Two recent sequences (2022001211 and 2022005897) cluster with historic Ugandan sequences from the 1950s. While the L-segment phylogenetic tree includes a Uganda/DRC specific Africa 2 clade.

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