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Fig 1.

Representative cattle management in close proximity to households, ZAIVE trial, Central Vietnam, 2019.

(Photographs captured by study authors).

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Table 1.

Ivermectin dosages administered, and treatment coverage, ZAIVE trial, Central Vietnam, 2019.

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Fig 2.

Total anopheline captures by trapping-night before and after intervention by treatment arm (A) and by village (B), ZAIVE trial, 2019, Central Vietnam.

Number of captured female anophelines in the control arm (blue circles) and the treatment arm (red triangles) over twelve trapping-nights. Values in Panel A represent aggregate mosquito captures across study arm (aggregated treated or controlled villages). Values in Panel B represent counts of mosquitoes captured, by individual village.

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Table 2.

Anopheles species diversity metrics, ZAIVE trial, Central Vietnam, 2019.

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Fig 3.

Count of Anopheles species captured nightly, ZAIVE trial, 2019, Central Vietnam.

Count of female Anopheles mosquitoes captured with a cattle-baited trap stratified by mosquito species. Values above each treatment and control period are the calculated Brillouin’s Index of population diversity.

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Table 3.

Results from the primary difference-in-differences analysis, ZAIVE trial, Central Vietnam, 2019.

Results from the generalized estimating equations with a negative binomial distribution. Confidence intervals and p-values were calculated using robust standard errors. The main outcome metric is the interaction term, assessing the difference-in-difference change in mosquito populations due to both time and intervention. The incidence rate ratio and the p-value do not show any statistically significant impacts on the anopheline mosquito captures in the treated groups compared to the control groups across the study periods.

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Fig 4.

Brillouin’s species diversity index by village by trapping-night, ZAIVE trial, 2019, Central Vietnam.

Brillouin’s index was calculated for each trapping-night in each village. Orange markers represent the maximum captured diversity, while green represents the minimum captured diversity.

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Fig 5.

Village-level trends in anopheline population richness and evenness, ZAIVE trial, 2019, Central Vietnam.

Calculated richness and evenness for each village, by trapping-night. Crosses represent the pre-intervention trap-nights, and open circles represent post-intervention trap-nights. Numbers in circles represent the specific trap-night. Higher values on the y-axis represent increased species diversity, and greater values on the x-axis represent increasing species richness.

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