Fig 1.
PECO research question.
Fig 2.
Flow diagram of the systematic review selection.
Fig 3.
Distribution of articles included in the Systematic Review by country of analysis (A) and estimated prevalence of Chagas Disease per 100,000 inhabitants in 2019 (B). Note: Maps were created using Geopandas package within Python environment, version 3.10.0. The base map used is derived from an openly available ESRI shape file source (https://hub.arcgis.com/datasets/esri::world-countries-generalized). Prevalence data are available at IHME (https://vizhub.healthdata.org/gbd-compare/), and investigated countries were collected from the 15 studies included in the systematic review.
Table 1.
Attributes of the studies included in the systematic review (n = 15).
Table 2.
Quality assessment of the included studies.
Table 3.
Cost components included in the selected articles.
Table 4.
Summary statistics of selected cost components for the chronic phase of Chagas disease (2022 US$ PPP).