Fig 1.
Summary of incidence and case fatality rate (CFR) of human SFTSV infection from 2013 to 2021.
Annual incidence (Dotted and triangle) and CFR (Line and circle) of the SFTSV in China (Green), Japan (Black), and South Korea (Red) from 2013 to 2021. The plot was reconstructed from the statistics of national surveillance reports in China [15], Japan [16], and South Korea [17].
Fig 2.
Phylogenetic relationships of SFTSV.
The maximum clade credibility tree of the (A) Long (L), (B) Medium (M), (C) Short (S) gene segments was reconstructed using the Bayesian evolutionary interference method. The brackets in the x-axis display the genotype classification by Fu et al (2016). The phylogenetic branches with specific countries were color labeled black (China), red (Japan), and blue (South Korea), respectively.
Fig 3.
Evolutionary rate and the time of most recent common ancestor (tMRCA) of three gene segments in SFTSV by three countries.
(A) The Evolutionary rate and (B) tMRCA of Long (L), Medium (M), Short (S) gene segments were summarized by median and 95% HPD.
Table 1.
The estimates of the evolutionary rate and the time to the most recent common ancestor (tMRCA) in the phylogenetic analysis for SFTSV.
Fig 4.
Reassortment between pairs of three gene segments in SFTSV.
(A) Reassortment of the L and M gene, (B) the L and S gene (C) the M and S gene segments. The red line between phylogeny depicted gene reassortment between two genes. The brackets in the y-axis display the genotype classification by Fu et al (2016).
Table 2.
Molecular selection pressure of the SFTSV genomes.