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Fig 1.

Flow diagram of patient enrollment treatment and follow-up.

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Table 1.

Injection dose for different body parts for local blocking therapy.

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Table 2.

Comparison of general data of cobra bite patients between the two groups.

(Mean±SD).

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Table 3.

Comparison of wound necrosis volume with Cobra bite between two groups of patients.

(Mean±SD).

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Fig 2.

Comparison of wound healing time with cobra bite between two groups of patients.

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Fig 3.

A. The wound surface on the third day of treatment in the control group; A shows small thrombus and B shows necrotic adipose tissue. C shows necrotic adipose tissue. Fig 3B. The wound surface on the third day of treatment in the experimental group; C shows necrotic adipose tissue.

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Fig 4.

A. Pathological section staining of the patient’s wound in the control group (the microscopy magnification: 400X); A shows normal cells with nuclear staining morphology, B shows cells with fragmented nuclei, C shows cells with lobulated nucleus and D shows cells with irregularly polymorphic nuclei. Fig 4B. Pathological section staining of the patient’s wound in the experimental group (the microscopy magnification: 400X); E shows cells with lobulated nucleus and F shows the cells with blurred edges nucleus.

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