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Fig 1.

Schematic illustration of the study design.

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Table 1.

Demographics and clinical characteristics of patients with SFTS.

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Table 2.

Symptomatic and signs characteristics of patients with SFTSV infection on admission.

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Table 3.

Laboratory results of patients with SFTS on admission.

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Fig 2.

Receiver operating characteristic (ROC) curves for evaluating the predictive ability of the factors associated with severity of SFTS on admission.

(A) The combination of the EOS% and BAS% (orange line) had an AUC of 0.82 (P = 0.000); AST (blue line) had an AUC of 0.805 (P = 0.000); DBIL (red line) had an AUC of 0.777 (P = 0.000); Age (green line) had an AUC of 0.764 (P = 0.000). (B) The combination of the EOS% and BAS% (green line) had an AUC of 0.828 (P = 0.000); De-Ritis ratio (red line) had an AUC of 0.775 and the cut-off value was 2.69 (P = 0.000); NLR (blue line) had an AUC of 0.611 and the cut-off value was 2.27 (P = 0.083). Abbreviations: EOS: Eosinophils, BAS: Basophils, AST: Aspartate aminotransferase, DBIL: Direct Bilirubin, AUC: Area under the ROC curve, CI: Confidence interval, De-Ritis ratio: AST/ALT ratio, NLR: Neutrophil-to-lymphocyte ratio.

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Table 4.

Predictive value of risk factors for SFTS severity.

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Table 5.

Clinical characteristics of patients with SFTS, according the EOS% cutoff value on admission.

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Table 6.

Clinical characteristics of patients with SFTS, according to the BAS% cutoff value on admission.

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Fig 3.

Correlation among circulating EOS%, BAS%, and laboratory parameters in SFTS patients.

Abbreviations: MON: Monocyte, EOS: Eosinophils, BAS: Basophils, PCT: Procalcitonin, CRP: C-reactive protein, LDH: Lactate dehydrogenase, CK: Creatine phosphokinase, AST: Aspartate aminotransferase, ALB: Albumin, GGT: γ-glutamyl transferase, ALP: Alkaline phosphatase, CREA: Creatinine.

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