Fig 1.
Study flow chart.
Table 1.
Baseline characteristics of patients with loxoscelism.
Fig 2.
Marbled macula, with and without erythematous halo, after a Loxosceles sp. bite.
(a) 18 h after the bite; (b) 24 h after the bite; (c) 72 h after the bite; (d) 120 h after the bite.
Fig 3.
A patient bitten at two sites on the right arm.
Marbled maculae on the forearm (a) and the upper arm (b), 4 days after a Loxosceles sp. bite. (c) Necrotic lesion on the upper arm and forearm 19 days after the bite.
Fig 4.
Evolution of a cutaneous lesion after a Loxosceles sp. bite.
(a) marbled macula with blister, 7 days after the bite; (b) cutaneous lesion with a ruptured blister, 12 days after the bite; (c) eschar, 32 days after the bite.
Fig 5.
Evolution of a cutaneous lesion after a Loxosceles sp. bite, from marbled macula to necrosis and ulcer.
(a) 4 days after the bite; (b) 17 days after the bite; (c) 24 days after the bite; (d) 31 days after the bite.
Fig 6.
Evolution of the cutaneous lesion after a Loxosceles sp. bite in a patient with cutaneous-hemolytic loxoscelism.
(a) 8 days after the bite; (b) 17 days after the bite; (c) 24 days after the bite; (d) 52 days after the bite.
Fig 7.
Evolution of a cutaneous lesion after a Loxosceles sp. bite, from marbled macula to necrosis and ulcer.
(a) 5 days after the bite; (b) 20 days after the bite; (c) 27 days after the bite, the patient presented an ulcer at the bite site and scaling on the hands; (d) 83 days after the bite, the patient had a scar at the site of the bite but opted not to undergo plastic surgery.
Table 2.
Systemic manifestations observed at hospital admission.
Fig 8.
Evolution of a cutaneous lesion after a Loxosceles sp. bite.
Marbled macula at the bite site (a), rash on the forearm (b), and rash on the abdomen (c), 4 days after the bite. (d) Persistence of the rash on the abdomen at 7 days after the bite.
Fig 9.
Rash on the thighs and palmar erythema in a patient bitten by a Loxosceles sp. spider, 4 days after the bite.
Fig 10.
Patients bitten by a Loxosceles sp. spider and presenting desquamation on the feet and hands.
(a) 17 days after the bite; (b) 24 days after the bite; (c) 36 days after the bite.
Table 3.
Duration of systemic manifestations.
Table 4.
Comparison between patients who developed skin necrosis and those who did not.
Table 5.
Frequency of cutaneous necrosis among patients who did and did not receive anti-arachnid serum, by the time from bite to antivenom administration.