Fig 1.
Flow chart of the retrospective study of leprosy as IRIS in French Guiana between 2000 and 2020.
Fig 2.
IRIS type 1 after introduction of HAART in patient 3: TT on left flank.
A: at diagnosis of leprosy; B: on MDT and HAART; C: cured at M18 (continued MDT and HAART).
Fig 3.
IRIS type 1 after introduction of HAART in patient 4: BT leprosy on the left ear and cheek with hypertrophy of the great auricular nerve.
Fig 4.
IRIS type 4 after introduction of HAART in patient 5: BT leprosy in T1R on the right flank.
Fig 5.
IRIS type 1 after introduction of HAART in patient 6: BT leprosy in T1R on the trunk.
A: multiple inflammatory papulo-nodular lesions. B: close-up view of the lesion on the right shoulder.
Table 1.
Epidemiological, clinical and biological characteristics of the 6 patients included in the retrospective study diagnosed with leprosy as IRIS in French Guiana between 2000 and 2020.
M: male; RNA: ribonucleic acid; SL: skin lesion(s); T1R: type 1 reaction; U: ulceration; NT: neuritis; NFI: nerve fonction impairment; Se: sensitive; Mo: motor; 1: before MDT introduction; 2: after MDT introduction; TT: polar tuberculoid; BT: borderline tuberculoid; BB: borderline borderline; PB: paucibacillary; MB: multibacillary.
Fig 6.
Flow chart of the systematic review of leprosy as IRIS according to the PRISMA 2020 criteria.
Table 2.
Number and proportion of patients diagnosed with leprosy IRIS included in the systematic review.
Fig 7.
Distribution of patients according to time from HAART introduction to leprosy IRIS.