Fig 1.
Leprosy Suspicion Questionnaire (LSQ).
Table 1.
Number of individuals ranked according to total signs and symptoms of leprosy marked on the LSQ in order of frequency (n = 1,054).
Table 2.
Distribution of crossing frequencies between the five most marked questions of LSQ and respective risk relatives.
Table 3.
Demographic characterization of Leprosy and Non-Leprosy groups.
Fig 2.
Images of different locations (buttock, elbow, foot, and knee) of leprosy lesions.
(a) Hypochromatic macule on the left buttock; (b) the same patient, after performing the endogenous histamine test, below the initial macule observed, another hypochromatic, hypo-anesthetic macule became more evident due to the erythema surrounding the lesion; (c) hypochromatic anesthetic macule on the right elbow; (d) residual hypochromatic macule on the right elbow after 12 months of multi drug therapy; (e-f) hypochromatic hypo-anesthetic macules on the left foot; (g) the same previous patient with improvement of skin sensitivity with more normoesthesic points; (h) hypochromatic hypo-anesthetic macule on the left knee. Legend: 0 (anesthetic point);—(hypoesthetic point); + (normoesthesic point).
Table 4.
Clinical characterization of Jardinópolis patients regarding the percentage of positivity to the clinical criteria used for the diagnosis of leprosy (n = 64).
Table 5.
Results of anti-PGL-I antibody measurements (anti-PGL-I index; cut off 0.295).
Fig 3.
Spatial distribution of all LSQ applied specifically in the northwest (A), population sample of evaluated individuals (B), new cases of leprosy cases all over the municipality (C), hotspot of cases clustered in the center of northwest region (D), anti-PGL-I indexes in NLG in all regions with high indexes around the LG cases (E), and one zoon street view demonstrates the closed neighborhood with individuals with positive anti-PGL-I indexes around new cases in the same street of northwest region in the Jardinópolis (SP, Brazil) geographic area. www.openstreetmap.org.
Fig 4.
Images of different locations (elbow, arm, leg, buttock, anterior and posterior trunk) of leprosy lesions.
(a) Hypochromatic anesthetic macule with irregular edges on the right elbow and forearm; (b) the same previous patient, after 12 months of multi drug therapy, with improvement of skin sensitivity; (c-d) typical borderline lesions on the left arm and trunk; (e) hypochromatic macule with infiltrated erythematous border on the right leg; (f) typical borderline lesions on the buttocks; (g) hypochromatic macules and erythematous plaques on the back; (h) the same previous patient, after 3 months of multi drug therapy with new hypochromatic macules on the back. Legend: 0 (anesthetic point);—(hypoesthetic point); + (normoesthesic point).
Table 6.
Clinical data and follow up in the leprosy patients treated.
Table 7.
Prevalence, new cases and new case detection rate (NCDR) in Jardinópolis from 2010 to 2019.