Fig 1.
Abbreviation: PDH = Progressive disseminated histoplasmosis.
Table 1.
Clinical characteristics of the patients included in the study.
Fig 2.
Flowchart of urine samples submitted to the three urine Histoplasma antigen detection tests.
Abbreviation: IAHE = IMMY ALPHA Histoplasma EIA kit. cHGEI IMMY = clarus Histoplasma GM Enzyme Immunoassay. MVHUALFA = MiraVista Histoplasma Urine Antigen LFA. PDH = Progressive disseminated histoplasmosis. No inconclusive results were found.
Fig 3.
Distribution of the 391 samples analyzed with the three urine Histoplasma antigen detection tests.
Abbreviation: IAHE = IMMY ALPHA Histoplasma EIA kit. cHGEI IMMY = clarus Histoplasma GM Enzyme Immunoassay. MVHUALFA = MiraVista Histoplasma Urine Antigen LFA. AD = Additional diagnosis.
Table 2.
Performance evaluation of three urine Histoplasma antigen detection tests and two molecular tests for the diagnosis of progressive disseminated histoplasmosis in people living with human immunodeficiency virus.
Table 3.
Clinical and laboratory characteristics of proven-PDH cases with a negative result by all three urine Histoplasma antigen detection tests.
Table 4.
Clinical and laboratory characteristics of 25 patients with probable PDH and without additional diagnosis.
Table 5.
Clinical and laboratory characteristics of 16 patients with probable PDH and with an additional diagnosis.
Fig 4.
Flowchart of the samples subjected to Hcp100 nested PCR.
Abbreviation: PDH = Progressive disseminated histoplasmosis. No inconclusive results were found.
Fig 5.
Flowchart of the samples subjected to 1281−1283220 SCAR nested PCR.
Abbreviation: PDH = Progressive disseminated histoplasmosis. No inconclusive results were found.