Fig 1.
Correlation of quantitative results of the FAVNt and the Platelia-II ELISA performed on DBS and serum.
Panel A shows the correlation between the RVNA titer of DBS-FAVNt and the RVNA titer of undiluted serum measured with the FAVNt. Panel B shows the antibody titer of DBS-ELISA compared to the RVNA titer of undiluted serum measured with the FAVNt. Panel C shows the antibody titer of DBS-ELISA compared to the antibody titer of serum-ELISA. R represents the Spearman correlation coefficient. CI is confidence interval. Dashed lines represent the of 5% confidence bands of the best fit line (represented by solid lines).
Fig 2.
Bland-Altman plots of the mean titer of DBS and serum plotted against the difference between both values.
Panel A shows the average antibody titer (IU/ml) of the DBS and sera measured with the FAVNt on the x-axis and the value (IU/ml) of the DBS minus the value of the serum on the y-axis. Panel B shows the average value of the DBS-ELISA and the serum-FAVNt on the x-axis and the value of the DBS-ELISA minus the value of the serum-FAVNt on the y-axis. Panel C shows the mean antibody level of the DBS and sera measured with the Platelia-II-ELISA on the x-axis and the value of the DBS minus the value of the serum on the y-axis. The long-dashed lines close to y = 0 represent the mean bias, the short-dashed lines represent the 95% limits of agreement (mean bias ±1.96 times the SD).