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Table 1.

Assumptions to estimate disease burden in the routine and SDR-PEP intervention scenario.

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Fig 1.

SDR-PEP intervention (A) estimated cost and (B) predicted new cases detection rate per 100,000 persons. (A) Points represent the mean cost in US$ per year and the error bars represent the 95% uncertainty interval based on 1,000 simulation runs. (B) The black line represents the mean new case detection rate and shaded region represents the 95% uncertainty interval based on 1,000 simulation runs.

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Fig 2.

Estimated cumulative DALYs averted as a result of the SDR-PEP intervention under three assumptions of disability prevention.

Points represent the mean cumulative DALYs averted per year. The error bars represent the 95% uncertainty interval based on 1,000 simulation runs.

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Fig 3.

Cost-effectiveness plane and acceptability curve of assumption 1–3 at 25th year.

(A) Red dot represents the incremental cost-effectiveness ratio, and dotted line represents the threshold. (B) Blackline represent the cost-effectiveness acceptability curve.

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Fig 3 Expand

Table 2.

SDR-PEP incremental cost-effectiveness ratio and probability of cost-effectiveness at five year intervals.

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Table 2 Expand