Fig 1.
Brazil is geographically divided into five macroregions, and administratively into 26 states and one Federal District (DF).
Central-West (DF: Distrito Federal, GO: Goiás, MT: Mato Grosso and MS: Mato Grosso do Sul); North (AC: Acre, AM: Amazonas, AP: Amapá, RO: Rondônia and RR: Roraima); Northeast (AL: Alagoas, BA: Bahia, CE: Ceará, MA: Maranhão, PB: Paraíba, PE: Pernambuco, PI: Piauí, RN: Rio Grande do Norte and SE: Sergipe); South (PR: Paraná, RS: Rio Grande do Sul and SC: Santa Catarina); Southeast (ES: Espírito Santo, MG: Minas Gerais, RJ:Rio de Janeiro and SP: São Paulo). Public domain digital maps were obtained from the Brazilian Institute of Geography and Statistics (IBGE) cartographic database in shapefile format (.shp), which was subsequently reformatted and analyzed using QGIS version 3.10 (Geographic Information System, Open Source Geospatial Foundation Project. http://qgis.osgeo.org).
Fig 2.
Global rates (expressed at 3-year moving averages) of ACD notifications in Brazil per 100,000 inhabitants (2002 to 2017) according to SINAN.
Three periods were identified by Joinpoint regression using APC (Annual Percentage Change) calculations: Period 1 (2001–2005), Period 2 (2005–2009) and Period 3 (2009–2018).
Table 1.
Data stratified by sociodemographic variables, self-reported skin color and probable route of Trypanosoma cruzi infection during the period under study (2001–2018) of acute Chagas disease notifications*.
Fig 3.
Analysis of changes in profiles of sociodemographic variables, self-reported skin color and probable route of Trypanosoma cruzi infection by region, stratified according three periods (P1, P2 and P3) of acute Chagas disease notifications as determined by annual percentage changes.
Public domain digital maps were obtained from the Brazilian Institute of Geography and Statistics (IBGE) cartographic database in shapefile format (.shp), which was subsequently reformatted and analyzed using QGIS version 3.10 (Geographic Information System, Open Source Geospatial Foundation Project. http://qgis.osgeo.org).
Fig 4.
Spatiotemporal distribution of relative risk of ACD by microregion, based on number of case notifications (SINAN-Brazilian Ministry of Health, Brazil, 2002–2017).
Public domain digital maps were obtained from the Brazilian Institute of Geography and Statistics (IBGE) cartographic database in shapefile format (.shp), which was subsequently reformatted and analyzed using QGIS version 3.10 (Geographic Information System, Open Source Geospatial Foundation Project. http://qgis.osgeo.org).