Fig 1.
Flow chart of study selection process.
Table 1.
Characteristics of studies included in the meta-analysis.
Fig 2.
Forest plots of sensitivity and specificity of studies using rrs as the target gene for the detection of Leptospira.
Fig 3.
Forest plot of DOR of targeting the rrs gene in the detection of Leptospira.
Fig 4.
SROC curve of targeting the rrs gene in the detection of Leptospira.
Table 2.
Meta-analysis results of studies targeting the rrs gene for the detection of Leptospira.
Fig 5.
Forest plots of sensitivity and specificity of studies using lipL32 as the target gene for the detection of Leptospira.
Fig 6.
Forest plot of DOR of targeting the lipL32 gene in the detection of Leptospira.
Fig 7.
SROC curve of targeting the lipL32 gene in the detection of Leptospira.
Table 3.
Meta-analysis results of studies targeting the lipL32 gene for the detection of Leptospira.
Fig 8.
Forest plots of sensitivity and specificity of studies using secY as the target gene for the detection of Leptospira.
Fig 9.
Forest plot of DOR of targeting the secY gene in the detection of Leptospira.
Fig 10.
SROC curve of targeting the secY gene in the detection of Leptospira.
Table 4.
Meta-analysis results of studies targeting the secY gene for the detection of Leptospira.
Fig 11.
Forest plots of sensitivity and specificity of studies using flaB as the target gene for the detection of Leptospira.
Fig 12.
Forest plot of DOR of targeting the flaB gene in the detection of Leptospira.
Fig 13.
SROC curve of targeting the flaB gene in the detection of Leptospira.
Table 5.
Summary of diagnostic accuracy measures of genetic markers for the detection of Leptospira in clinical samples.