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Fig 1.

Transmission cycle of Y. pestis in a plague-endemic community [37].

Under favourable environmental conditions, populations of rodent species that are very susceptible to plague infection (T. leucogaster and Mastomys coucha) increase to high levels [38]. If these population increases occur in an area where there is a quiescent plague focus, the plague may break out in the susceptible rodent population. In plague-endemic areas, this population increase is crucial in plague transmission because a large number of mice and rats correspond to a large number of fleas [38]. Plague kills the susceptible rodents, and their infected fleas leave the carcass and seek new hosts, thereby spreading the infection rapidly throughout areas of high population.

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Table 1.

Recorded human plague cases from 1974 to 2018 in Hwange, Nkayi, and Lupane, Matabeleland North Province, Zimbabwe.

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