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Table 1.

Molluscicidal activity of quaternary benzodiazepine alkaloids (QBAs) from Macleaya cordata fruits on Oncomelania hupensis.

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Fig 1.

Effects of quaternary benzo[c]phenanthridine alkaloids from Macleaya cordata fruits on glutathione S-transferase (GST) activity in the liver of Oncomelania hupensis snails.

Note: Different lowercase letters in the same color grid of different columns indicate significant differences at the same concentration with different treatment times; different uppercase letters in different color grids of the same column indicate significant differences at different concentrations with the same treatment times (P < 0.05). CK: Control.

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Fig 1 Expand

Fig 2.

Effects of quaternary benzo[c]phenanthridine alkaloids from Macleaya cordata fruits on carboxylesterase (CarE) activity in the liver of Oncomelania hupensis snails.

Note: Different lowercase letters in the same color grid of different columns indicate significant differences at the same concentration with different treatment times; different uppercase letters in different color grids of the same column indicate significant differences at different concentrations with the same treatment times (P < 0.05). CK: Control.

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Fig 2 Expand

Fig 3.

Effects of quaternary benzo[c]phenanthridine alkaloids from Macleaya cordata fruits on acid phosphatase (ACP; A) and alkaline phosphatase (AKP; B) activity in the liver of Oncomelania hupensis snails.

Note: Different lowercase letters in the same color grid of different columns indicate significant differences at the same concentration with different treatment times; different uppercase letters in different color grids of the same column indicate significant differences at different concentrations with the same treatment times (P < 0.05). CK: Control.

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Fig 3 Expand

Fig 4.

Chromatogram of quaternary benzo[c]phenanthridine alkaloids in Macleaya cordata fruits determined by HPLC-MS.

Note: The peak at 338 was an impurity peak in the HPLC-MS spectrometer.

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Fig 4 Expand

Fig 5.

Chromatogram of sanguinarine (SA) standard sample determined by HPLC-MS.

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Fig 5 Expand

Fig 6.

Chromatogram of chelerythrine (CHE) standard sample determined by HPLC-MS.

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Fig 6 Expand

Fig 7.

Mass spectrogram of quaternary benzo[c]phenanthridine alkaloids (BasePeak:332).

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Fig 7 Expand

Fig 8.

Mass spectrogram of quaternary benzo[c]phenanthridine alkaloids (BasePeak:348).

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Fig 9.

Mass spectrogram of sanguinarine (SA) standard sample.

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Fig 9 Expand

Fig 10.

Mass spectrogram of chelerythrine (CHE) standard sample.

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Fig 10 Expand