Table 1.
Geographical origin and year of isolation of the Salmonella enterica Typhi, Paratyphi A, Typhimurium and Enteritidis strains.
Fig 1.
Venn diagram of the orthologous proteins detected by LC-MS/MS in 6 Salmonella Typhi, 6 Salmonella Paratyphi A, 6 Salmonella Enteritidis and 6 Salmonella Typhimurium strains.
Fig 2.
Principal component analysis (PCA) separate serovars based on LFQ intensities.
The PCA plots show that the first and second principle components capture ~72% of the variability among the Salmonella serovars Typhi (STY), Paratyphi A (STPA), Typhimurium (STM) and Enteritidis (SENT) (A), 80% of the variability between the serovars STY and SPTA (B), and ~80% of the variability between the serovars STM and SENT (C). Reference strains for each serovar are presented in red.
Table 2.
Gene ontology functional enrichment analysis of differentially expressed core proteins between typhoidal and non-typhoidal, Typhi and Paratyphi A, Enteritidis and Typhimurium Salmonella.
Fig 3.
Phenetic sub-network inference analysis of differential protein expression in STY versus SPTA.
122 out of 230 differentially expressed proteins are shown in this sub-network. Red nodes represent proteins with higher expression in SPTA versus STY. Green nodes represent proteins with higher expression in STY versus SPTA. The more intense the color, the higher the level of differential expression. Gray nodes have no differential expression. The color of the edge indicates the interaction type with blue referring to metabolic, green to protein-protein and red to protein-DNA interactions.
Fig 4.
Phenetic sub-network inference analysis of differential protein expression in STM versus SENT.
78 out of 192 differentially expressed proteins are shown in the sub-network. Red nodes represent proteins with higher expression in SENT versus STM. Green nodes represent proteins with higher expression in STM versus SENT. The more intense the color, the higher the level of differential expression. Gray nodes have no differential expression. The color of the edge indicates the interaction type with blue referring to metabolic and orange to protein-DNA interactions.