Fig 1.
Weekly attack rate of suspected meningitis in Dogondoutchi (red), Tibiri (blue), Dioundiou (green), Gaya (black), and in the whole study area (purple).
Table 1.
Number of cases and population across study area.
Fig 2.
Schematic of the reactive prophylaxis protocol.
Description of the reactive prophylaxis protocol, in the pre-epidemic, epidemic, and contact prophylaxis stages.
Table 2.
Parameters, meanings, and values considered.
Table 3.
Household and village clustering metrics.
Fig 3.
Potential effectiveness and efficiency of village-prophylaxis strategies by epidemic threshold definition.
Total number treated, potentially prevented cases (PPC) and number needed to treat per PPC from applying a village-prophylaxis strategy, varying the threshold for intervention, with surveillance at different spatial units (colors).
Fig 4.
Potential effectiveness and efficiency of prophylaxis strategies by radius of prophylaxis.
Total number treated, potentially prevented cases (PPC) and number needed to treat per PPC by radius of prophylaxis, varying the health area-level threshold for intervention start (line type).
Fig 5.
Potentially effectiveness and efficiency of village-antibiotic and village-vaccination prophylaxis strategies.
Potentially prevented cases (PPC) and number needed to treat/vaccinate per PPC from applying a village-prophylaxis antibiotic (blue) and vaccination (green) strategy, varying the threshold for intervention at the health area level.
Table 4.
Potential effectiveness and efficiency of village-prophylaxis strategies across a range of parameters.