Fig 1.
Spatial distribution of HTLVs infection and seroprevalence among rural population in Gabon, central Africa.
*: Province with HTLV-2 infection; N: Number of HTLV-positive sample. Dotted line: main roads. Red circle: villages with HTLV-1 infection. Orange circle: villages with HTLV-2 infection. White circle: village with no HTLV positive sample. Location of villages was strictly geo-referenced and maps were generated by MAPINFO software (https://www.pitneybowes.com/us/location-intelligence/geographic-information-systems/mapinfo-pro.html).
Table 1.
Prevalence of HTLV-1 and indeterminate serological status by province among rural population in Gabon, central Africa.
Table 2.
Prevalence of HTLV-1 by sex and age among rural population in Gabon, central Africa.
Fig 2.
HTLV-1/2 proviral load by sex and age among rural population in Gabon, central Africa.
Rectangle: Average magnitude of HTLV1/2 proviral load; Line: Median proviral load; Bar: Standard deviation. HTLV-1/2 proviral load was measured by a multiplex real-time PCR assay involving a molecular beacon probe for simultaneous detection, differentiation, and quantification of HTLV-1, -2, and -3 and STLV-1 and -3.
Table 3.
Risk factors for infections with HTLV-1 compare to negative or indeterminate serological status among rural population in Gabon, central Africa.
Fig 3.
LTR phylogenetic analysis of HTLV-1 strains from Gabon.
Phylogenetic tree was obtained on a 466bp LTR sequence using available sequences from Genbank. The 87 new HTLV-1 Gabonese strains are shown by bold circle. PTM3 (STLV-1 strain) was used to root the tree. The numbers along ancestral segments indicate the robustness of each node, as estimated by 1000 bootstrap samplings of the data. The Genbank accession numbers of the new sequences in the phylogenetic tree are JF270481 to JF270597.